AutismKB 2.0

Annotation Detail for FOXJ3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:FOXJ3 ( MGC165036,MGC176686 )
Gene Full Name: forkhead box J3
Band: 1p34.2
Quick LinksEntrez ID:22887; OMIM: NA; Uniprot ID:FOXJ3_HUMAN; ENSEMBL ID: ENSG00000198815; HGNC ID: 29178
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of FOXJ3 mRNAdecreases expression 19150397
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of FOXJ3 mRNAaffects binding|decreases expression|increases activity 19710929
D013629 Tamoxifen Tamoxifen results in increased expression of FOXJ3 mRNAincreases expression 17555576
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 5.4114745880
MESH:D055371 Acute Lung Injury pirinixic acid 3.6418653653
MESH:D018248 Adenoma, Liver Cell pirinixic acid 4.2216434500
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.6319483382
MESH:D001943 Breast Neoplasms Tamoxifen 2.1617261762 20544844 18425577 19011961 18821012 18351453 18629630 19189212 19288272 18855134 17440819 17893378 18984771 15565566 19059307 18815881 19244106 19189210 16873071 11161223 19289846 19221464 19487384 20135344 19066611 19142967 20390343 19115204 18997820 16202921 20005174 21138602 19200415 19410462 17242785 15668708 16273361 19084267 17049068 20065188 19103187 20859285 16818667 21152245 19155303
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 5.1619066611
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 1.8616924424
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 4.0617572228
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 3.0120889678
MESH:D002779 Cholestasis pirinixic acid 3.1519176532
MESH:D003711 Demyelinating Diseases Tamoxifen 5.0219031437
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5918249437
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.8919279558
MESH:D004487 Edema pirinixic acid 2.9612083418
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 4.1219031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 3.3117893378 20544844 16202921 19155303
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1520426865
MESH:D005234 Fatty Liver pirinixic acid 9.3219236843 20131406
MESH:D005234 Fatty Liver Tamoxifen 9.3219224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.4716709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 5.2714745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.9219069698
MESH:D006333 Heart Failure pirinixic acid 2.7820558911
MESH:D006529 Hepatomegaly pirinixic acid 3.6419772884 16221962 18467677 19176532
MESH:D006943 Hyperglycemia pirinixic acid 3.6320558911
MESH:D007249 Inflammation Tamoxifen 2.5519457130
MESH:D007333 Insulin Resistance pirinixic acid 2.9016306350
MESH:D007680 Kidney Neoplasms Tamoxifen 3.4318625569
MESH:D008064 Lipidoses Tamoxifen 3.4615342952 17567588
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 2.4215474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 2.4218564211
MESH:D008113 Liver Neoplasms pirinixic acid 4.8820007298 16377806 15890375
MESH:D008113 Liver Neoplasms Tamoxifen 4.8816684651
MESH:D008175 Lung Neoplasms Tamoxifen 1.7518625569
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 4.5019428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.8811731420 16827153 14580682 19196723 19196722
MESH:D020149 Manganese Poisoning Tamoxifen 5.4119453300
MESH:D008545 Melanoma Tamoxifen 1.9219393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.9215990972
MESH:D009135 Muscular Diseases pirinixic acid 4.1616239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.2919151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.2916411023
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.6819393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.6219410462
MESH:D009369 Neoplasms pirinixic acid 2.1217405874
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.8719189210 19196722 19200415
MESH:D009765 Obesity pirinixic acid 1.8920558911
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.0815067354
MESH:D015427 Reperfusion Injury pirinixic acid 2.5619058328
MESH:D013088 Spermatocele Tamoxifen 5.1616709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.7819457130
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 2.4916712894 8653321 17572228
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved