AutismKB 2.0

Annotation Detail for FKBP5


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:FKBP5 ( AIG6,FKBP51,FKBP54,MGC111006,P54,PPIase,Ptg-10 )
Gene Full Name: FK506 binding protein 5
Band: 6p21.31
Quick LinksEntrez ID:2289; OMIM: 602623; Uniprot ID:FKBP5_HUMAN; ENSEMBL ID: ENSG00000096060; HGNC ID: 3721
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
No data
Pathway IDPathway Name
200077Glucocorticoid receptor regulatory network
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1860Brain tumor
1907Depression
1943Adenocarcinoma
2041Myelofibrosis
1874Stress disorder, post-traumatic
Desease Name
PSYCH
depression
No data
Desease Name
Major depressive disorder and accelerated response to antidepressant drug treatment
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C049325 1,2-dithiol-3-thione 1,2-dithiol-3-thione results in increased expression of FKBP5 mRNAincreases expression 15375163
C020365 17-alpha-hydroxy-progesterone caproate 17-alpha-hydroxy-progesterone caproate inhibits the reaction [Dexamethasone results in increased expression of FKBP5 mRNA]decreases reaction|increases expression 19255438
C020365 17-alpha-hydroxy-progesterone caproate 17-alpha-hydroxy-progesterone caproate inhibits the reaction [NR3C1 protein results in increased expression of FKBP5 mRNA]decreases reaction|increases expression 19255438
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of FKBP5 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene results in decreased expression of FKBP5 mRNAdecreases expression 20406850
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of FKBP5 mRNAaffects expression 21346803
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in decreased expression of FKBP5 mRNAdecreases expression 12958071
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of FKBP5 mRNAincreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of FKBP5 mRNAaffects expression 17562736
C109238 acyline acyline results in decreased expression of FKBP5 mRNAdecreases expression 17510436
D013196 Dihydrotestosterone Dihydrotestosterone results in increased expression of FKBP5 mRNAincreases expression 18007998
D001262 Atenolol Atenolol results in decreased expression of FKBP5 mRNAdecreases expression 19915711
C017037 aurin aurin inhibits the reaction [Dexamethasone results in increased expression of FKBP5 mRNA]decreases reaction|increases expression 19255438
C017037 aurin aurin inhibits the reaction [NR3C1 protein results in increased expression of FKBP5 mRNA]decreases reaction|increases expression 19255438
D001554 Benzene Benzene results in increased expression of FKBP5 proteinincreases expression 15036117
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FKBP5 mRNAaffects cotreatment|increases expression 18164116
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of FKBP5 mRNAdecreases expression 20382639
C006780 bisphenol A bisphenol A results in decreased expression of FKBP5 mRNAdecreases expression 18007998
C099555 CD 437 CD 437 results in decreased expression of FKBP5 mRNAdecreases expression 12958071
C011585 ciclopirox ciclopirox inhibits the reaction [Dexamethasone results in increased expression of FKBP5 mRNA]decreases reaction|increases expression 19255438
D016572 Cyclosporine Cyclosporine results in decreased expression of FKBP5 mRNAdecreases expression 20106945
C017180 decamethrin decamethrin results in increased expression of FKBP5 mRNAincreases expression 19017407
D003907 Dexamethasone 17-alpha-hydroxy-progesterone caproate inhibits the reaction [Dexamethasone results in increased expression of FKBP5 mRNA]decreases reaction|increases expression 19255438
D003907 Dexamethasone aurin inhibits the reaction [Dexamethasone results in increased expression of FKBP5 mRNA]decreases reaction|increases expression 19255438
D003907 Dexamethasone ciclopirox inhibits the reaction [Dexamethasone results in increased expression of FKBP5 mRNA]decreases reaction|increases expression 19255438
D003907 Dexamethasone Dexamethasone results in increased expression of FKBP5 mRNAincreases expression 16144937
17690134
12732289
15679045
19255438
D003907 Dexamethasone Dexamethasone results in increased expression of FKBP5 proteinincreases expression 15679045
D003907 Dexamethasone Forskolin promotes the reaction [Dexamethasone results in increased expression of FKBP5 mRNA]increases expression|increases reaction 19255438
D003907 Dexamethasone Mifepristone inhibits the reaction [Dexamethasone results in increased expression of FKBP5 mRNA]decreases reaction|increases expression 17690134
D003907 Dexamethasone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FKBP5 mRNAaffects cotreatment|increases expression 16054899
D004041 Dietary Fats Dietary Fats results in decreased expression of FKBP5 mRNAdecreases expression 18042831
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FKBP5 mRNAaffects cotreatment|increases expression 18164116
D004317 Doxorubicin FKBP5 protein affects the reaction [Doxorubicin results in increased degradation of and results in decreased expression of NFKBIA protein]affects reaction|decreases expression|increases degradation 15571967
D004958 Estradiol [Progesterone co-treated with Estradiol] results in increased expression of FKBP5 mRNAaffects cotreatment|increases expression 17404688
D005472 Fluorouracil TP53 protein affects the reaction [Fluorouracil results in decreased expression of FKBP5 mRNA]affects reaction|decreases expression 15016801
D005576 Forskolin Forskolin promotes the reaction [Dexamethasone results in increased expression of FKBP5 mRNA]increases expression|increases reaction 19255438
D015056 1-Methyl-3-isobutylxanthine [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FKBP5 mRNAaffects cotreatment|increases expression 16054899
C008493 methylselenic acid methylselenic acid affects the expression of FKBP5 mRNAaffects expression 14617803
D015741 Metribolone Metribolone results in increased expression of FKBP5 mRNAincreases expression 17010675
16751804
D015741 Metribolone Metribolone results in increased expression of FKBP5 proteinincreases expression 17152098
D015735 Mifepristone Mifepristone inhibits the reaction [Dexamethasone results in increased expression of FKBP5 mRNA]decreases reaction|increases expression 17690134
D010126 Ozone Ozone results in increased expression of FKBP5 mRNAincreases expression 17460151
19555225
C041786 palm oil palm oil results in decreased expression of FKBP5 mRNAdecreases expression 18042831
D010269 Paraquat Paraquat results in increased expression of FKBP5 mRNAincreases expression 12595580
D010269 Paraquat Paraquat affects the expression of FKBP5 mRNAaffects expression 16854511
C023036 perfluorooctanoic acid perfluorooctanoic acid results in decreased expression of FKBP5 mRNAdecreases expression 17560707
D010634 Phenobarbital Phenobarbital results in increased expression of FKBP5 mRNAincreases expression 19270015
C006253 pirinixic acid pirinixic acid results in increased expression of FKBP5 mRNAincreases expression 18445702
18301758
D011374 Progesterone [Progesterone co-treated with Estradiol] results in increased expression of FKBP5 mRNAaffects cotreatment|increases expression 17404688
D011374 Progesterone Progesterone results in increased expression of FKBP5 mRNAincreases expression 17404688
18037150
C089730 rosiglitazone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FKBP5 mRNAaffects cotreatment|increases expression 16054899
D020123 Sirolimus Sirolimus binds to and results in decreased activity of FKBP5 proteinaffects binding|decreases activity 15571967
C017947 sodium arsenite sodium arsenite results in increased expression of FKBP5 mRNAincreases expression 17682005
D016559 Tacrolimus Tacrolimus inhibits the reaction [NR3C1 protein binds to FKBP5 protein]affects binding|decreases reaction 15697228
C004648 testosterone enanthate testosterone enanthate affects the expression of FKBP5 mRNAaffects expression 17440010
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of FKBP5 mRNAdecreases expression 18495758
16443690
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of FKBP5 mRNAincreases expression 17035482
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 6.806195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 6.8015322242 11752688 14514962
MESH:D055371 Acute Lung Injury pirinixic acid 2.7018653653
MESH:D000230 Adenocarcinoma Doxorubicin 6.3717418594
MESH:D000230 Adenocarcinoma Estradiol 6.3711473722
MESH:D000230 Adenocarcinoma Fluorouracil 6.3717638652
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 9.633712494
MESH:D000236 Adenoma beta-Naphthoflavone 9.6319389873
MESH:D000236 Adenoma Diethylnitrosamine 9.6310737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 21.1319061943 17162532 16434500 17620307 18056438 19052882
MESH:D018248 Adenoma, Liver Cell Phenobarbital 21.1317620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 21.1316434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 21.1316835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.2415276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.4416712894 17306315
MESH:D000382 Agricultural Workers' Diseases Paraquat 3.3211874814
MESH:D000419 Albuminuria Doxorubicin 4.1121441931
MESH:D000544 Alzheimer Disease Ozone 4.0815513908
MESH:D000544 Alzheimer Disease rosiglitazone 4.0819621015
MESH:D000740 Anemia Fluorouracil 7.3816511603 15504547 17963324
MESH:D000740 Anemia Tetrachlorodibenzodioxin 7.3811748828
MESH:D000741 Anemia, Aplastic Benzene 4.0214761424 17661222 11369114
MESH:D000799 Angioedema Acetaminophen 3.3810982225
MESH:D001161 Arteriosclerosis Dietary Fats 3.4515238619
MESH:D001169 Arthritis, Experimental Dexamethasone 3.2517659584
MESH:D001172 Arthritis, Rheumatoid Ozone 2.4415570426
MESH:D001249 Asthma Ozone 2.4916373670 17854713
MESH:D001321 Autistic Disorder Acetaminophen 2.3018445737
MESH:D001321 Autistic Disorder Sirolimus 2.3021115397
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.551440618 11289319
MESH:D001778 Blood Coagulation Disorders pirinixic acid 7.4219483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 7.4212125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.3315340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.4615746008
MESH:D001855 Bone Marrow Diseases Benzene 4.7716183116
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.2414601052
MESH:D001862 Bone Resorption bisphenol A 3.4611985600
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.8717868700
MESH:D001930 Brain Injuries Progesterone 3.8215665606 15845082 15380490
MESH:D001932 Brain Neoplasms Doxorubicin 3.4217150277
MESH:D001943 Breast Neoplasms Benzene 5.2817162533 11921183
MESH:D001943 Breast Neoplasms bisphenol A 5.2817123778
MESH:D001943 Breast Neoplasms Dietary Fats 5.2820435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 5.2817474063
MESH:D001943 Breast Neoplasms Doxorubicin 5.2815939500 17983394 18628466 18382427 16595493 16322301 16264153 17426702 18695136 16115903 15136595 15994142 19526202 17369602 16935488 16826403 15634643 15993339 15668708 11325840 18234424 15567936 16096432 15692762
MESH:D001943 Breast Neoplasms Estradiol 5.2814630087 19861407 12948864 17018787 17289903 17261762 16675129 18497071
MESH:D001943 Breast Neoplasms Fluorouracil 5.2815136595 16557594 19217205 16110121 18357371 18608205 16595493
MESH:D001943 Breast Neoplasms Progesterone 5.2816175315 15562024 17614352
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 5.2820435547
MESH:D016535 Bronchial Hyperreactivity Ozone 3.3215516495 18417511 18315731 19059883 17626835 14754758 16777450
MESH:D002100 Cachexia Ozone 4.2916183385
MESH:D002177 Candidiasis ciclopirox 6.6316640825
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.0116111702
MESH:D002276 Carcinoid Tumor Doxorubicin 10.8116051944
MESH:D002276 Carcinoid Tumor Fluorouracil 10.8116051944
MESH:D002277 Carcinoma Fluorouracil 6.9917121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 6.9916835633
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 23.9716705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 23.9716705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 23.977296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 23.973084413
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 23.9719519916 19171122 20101231 18393292 20007298 18210153 19107877 16807293 19383236 10672840 20524982 19208518 20935162 3084413 18494052 20514400 20432363 17761372 18056438 17055752 18971187 16878318 18691550 20084675 17428255 18785209 16681979 19335982 18665156 17978847 21159647 19394651 10737359 16328049 11831363 3581430 19418558 16502159 16779866 18788625 19822196 18506893 16830150 19539802 16569478 17138121 16698587 16288022 17162532 19052882 20727157 19701751 20214788 19919837 20512989 17173139 18978308 16540662 16935385
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 23.9716023760 18059187 16234567 17876044
MESH:D006528 Carcinoma, Hepatocellular Estradiol 23.9716924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 23.9717045692 16332177 18930000 16799960 17088986 17971768
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 23.9720935162 17173139 20007298 6705139 1701930
MESH:D006528 Carcinoma, Hepatocellular Sirolimus 23.9719335982
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 23.9717306315 15276417 16507464
MESH:D002278 Carcinoma in Situ bisphenol A 4.5317123778
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 9.457296757
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 9.4516201981 1485588
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 9.4518695887
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 9.616189445
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 9.6116757204 16280240 18986760 17066447
MESH:D002294 Carcinoma, Squamous Cell Sirolimus 9.6119435901
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 9.6118572023
MESH:D006332 Cardiomegaly Atenolol 6.4515969258
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.4518850075 18670907 16120746
MESH:D009202 Cardiomyopathies Doxorubicin 3.2317007740 17351982 17928571 16269455 16242529 18627295 17924179 15476868 17382496 17329180 17974986 15505089 16455267 16109756 17308081 17131338 16612575 17519947 15811867 16731534 15792986 16364871 16952015 16278810 16651473
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.7817334414 16243910
MESH:D002318 Cardiovascular Diseases Tacrolimus 4.3017703430
MESH:D002386 Cataract Acetaminophen 2.3110977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 26.926135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 26.927505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 26.9220889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 26.9212371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 26.9217174075 7505956 2727394 21159647
MESH:D002471 Cell Transformation, Neoplastic Estradiol 26.9218566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 26.9220056578 19524636
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.814080065
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.0519052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.0516835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 11.4219486331 9022650
MESH:D002779 Cholestasis Cyclosporine 11.4219486331
MESH:D002779 Cholestasis pirinixic acid 11.4219176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 1.9016354765 8697196 12621046 15340226 15668235
MESH:D003110 Colonic Neoplasms Dexamethasone 3.5915824018
MESH:D003110 Colonic Neoplasms Fluorouracil 3.5917172411 15001691 17016597 17725105 16340194 18772588 16510598 17287894 17018589 17169374
MESH:D015179 Colorectal Neoplasms Doxorubicin 2.5218259882 18802399
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.5217594712 17454858 17094418 18288408 17016601 20501625 15289873 17401013 16391804 18383874 14970324 16303861 17255274 15148649 18448328 16524972 17695437 16331619 18802399 18949393 16282729 18509181
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.6814669216 17141729
MESH:D019465 Craniofacial Abnormalities Benzene 5.0015643154
MESH:D019465 Craniofacial Abnormalities decamethrin 5.0019861644
MESH:D019465 Craniofacial Abnormalities Dexamethasone 5.0017728286
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 5.0010048152 20055451 15322242
MESH:D003490 Cyanosis 2,4-dinitrotoluene 9.4218551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 9.4218551238
MESH:D007644 Darier Disease Fluorouracil 4.3416733453
MESH:D003865 Depressive Disorder, Major marker/mechanism
MESH:D003872 Dermatitis Benzene 4.3215902427
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 5.618156756 18759878 2524372 12868966 8970840 14531868 11906362 11298694
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 5.6112438553
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2018249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.083621924 2952479
MESH:D003920 Diabetes Mellitus rosiglitazone 3.9217446233
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 6.3920387270
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 6.3912642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.3917107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.0319279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.0517187935
MESH:D003967 Diarrhea Dexamethasone 3.287237001
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 16.2718551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 16.2721346803 18551238
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 16.279328219 16192314 18692083 6679447 18648102 1440618 6482804 8291058 18289764 7440962 11289319 9653073 9022650
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 16.2712594235 16081117 10774834 16177239 19164858 17522070 15619225 11421492 11739529 12705907 16485898 15968718 19923254 12958197 2444490 19739265 11743745 19416960 10663392 14986274 11529661 11461765 16393943 19085960 18713872 14725611 19420014 16781746 12392966 11834606 17562736 16227642 19370779 17906064 16109766 10915739 18071297 14550746 12540782 11287661 12153990
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 16.2719107877
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 16.2717416283
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 16.2720420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.6319426721
MESH:D004362 Drug Toxicity Doxorubicin 6.9818602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 6.9811462148
MESH:D004381 Duodenal Ulcer Tacrolimus 4.7117202747
MESH:D050171 Dyslipidemias Dietary Fats 3.1218367378
MESH:D004421 Dystonia Phenobarbital 3.591851702
MESH:D004485 Eczema Dexamethasone 4.0312438553
MESH:D004487 Edema Dexamethasone 17.4019703484
MESH:D004487 Edema perfluorooctanoic acid 17.4017259670 12083418
MESH:D004487 Edema pirinixic acid 17.4012083418
MESH:D004487 Edema rosiglitazone 17.4012083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 17.4012711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.4415322242 18230668 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 3.3517692515
MESH:D016889 Endometrial Neoplasms Doxorubicin 6.5317359293
MESH:D016889 Endometrial Neoplasms Estradiol 6.5319148513 18566989 11473722
MESH:D004715 Endometriosis Mifepristone 13.0616134523
MESH:D004715 Endometriosis Progesterone 13.0616134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 13.069294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.6918037988
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.673659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.413922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.6520417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.166401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.817750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.573659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.6516302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 6.443581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 6.4420426865
MESH:D004938 Esophageal Neoplasms Fluorouracil 6.4417638652 15173087 16481741 16337965 16785472
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.6711564622
MESH:D005234 Fatty Liver Cyclosporine 20.3619224547
MESH:D005234 Fatty Liver Dietary Fats 20.3617967931 19551842 19004024 18296743
MESH:D005234 Fatty Liver Diethylnitrosamine 20.3620387270 21071580
MESH:D005234 Fatty Liver pirinixic acid 20.3619236843 20131406
MESH:D005234 Fatty Liver rosiglitazone 20.3619196556
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.0111858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.556705139
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 4.1319069698
MESH:D005355 Fibrosis Cyclosporine 12.1612168785 12639820
MESH:D005355 Fibrosis Dietary Fats 12.1618296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 12.1620067830
MESH:D005756 Gastritis Acetaminophen 3.2116983495
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.2216452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.768708960
MESH:D005909 Glioblastoma Doxorubicin 3.0517150277
MESH:D005910 Glioma Fluorouracil 2.6816145905
MESH:D005911 Gliosis Paraquat 4.7011124998
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.627505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.1310696789
MESH:D006086 Graft vs Host Disease Tacrolimus 5.4316376943
MESH:D006130 Growth Disorders Tacrolimus 4.6211041285
MESH:D006258 Head and Neck Neoplasms Doxorubicin 11.3415692506
MESH:D006258 Head and Neck Neoplasms Fluorouracil 11.3415162350 15102660 18337622
MESH:D006258 Head and Neck Neoplasms Sirolimus 11.3419435901
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.0810048152 11294989
MESH:D006331 Heart Diseases Doxorubicin 3.1718006777 16244372 17875725 12587719 16495754 18674790 14766674 16707910 16879835 16244371 16330681 16144979 17888722
MESH:D006333 Heart Failure Atenolol 10.3620082655
MESH:D006333 Heart Failure Doxorubicin 10.3617481944
MESH:D006333 Heart Failure pirinixic acid 10.3620558911
MESH:D006394 Hemangiosarcoma Doxorubicin 3.5015692506
MESH:D006402 Hematologic Diseases Benzene 4.2416183116
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.9715720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.9311000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.096705139
MESH:D006529 Hepatomegaly perfluorooctanoic acid 17.063609246
MESH:D006529 Hepatomegaly Phenobarbital 17.0616109766
MESH:D006529 Hepatomegaly pirinixic acid 17.0618467677 16221962 19772884 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 17.0615340226 16120746 12621046
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 2.907520565
MESH:D006558 Herpes Genitalis Estradiol 4.5715709030
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 5.2817440010
MESH:D006689 Hodgkin Disease Doxorubicin 6.2317606976 18501091 15147373
MESH:D006689 Hodgkin Disease sodium arsenite 6.2312676792
MESH:D019584 Hot Flashes Estradiol 3.2917088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.588697196 16959395 15340226 16354765 18606429
MESH:D006930 Hyperalgesia Acetaminophen 11.1116870215
MESH:D006930 Hyperalgesia perfluorooctanoic acid 11.1112083418
MESH:D006930 Hyperalgesia rosiglitazone 11.1112083418
MESH:D006937 Hypercholesterolemia Dietary Fats 3.1921332399
MESH:D006943 Hyperglycemia pirinixic acid 2.7920558911
MESH:D006949 Hyperlipidemias Dietary Fats 3.2021332399
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.5015034207
MESH:D006973 Hypertension Atenolol 14.3811593098 11910301 12022239 15969258 19249413 14597852 15188945 12717102 15453913 15237695 15614026 14700505
MESH:D006973 Hypertension Benzene 14.3817940673
MESH:D006973 Hypertension Cyclosporine 14.3810903974
MESH:D006973 Hypertension Dexamethasone 14.3817042910
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 14.3818850075 18670907
MESH:D006984 Hypertrophy Sirolimus 4.8219211884
MESH:D017379 Hypertrophy, Left Ventricular Atenolol 5.3115237695
MESH:C537153 Hypomagnesemia primary Tacrolimus 5.7011041285
MESH:D007022 Hypotension Tacrolimus 4.7011041285
MESH:D007077 Ileal Diseases 1-Methyl-3-isobutylxanthine 4.9818306037
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 3.9615869954
MESH:D007248 Infertility, Male Paraquat 5.904850670
MESH:D007248 Infertility, Male sodium arsenite 5.9012646999 15346721
MESH:D007249 Inflammation Dexamethasone 20.4011099482 8960868
MESH:D007249 Inflammation Dietary Fats 20.4020412841
MESH:D007249 Inflammation Diethylnitrosamine 20.4018785209
MESH:D007249 Inflammation perfluorooctanoic acid 20.4012083418
MESH:D007249 Inflammation Progesterone 20.4015869954
MESH:D007249 Inflammation rosiglitazone 20.4012083418
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 20.4012200463 12878042
MESH:D007299 Insect Bites and Stings decamethrin 5.3315189238
MESH:D007333 Insulin Resistance bisphenol A 19.9716393666
MESH:D007333 Insulin Resistance Dietary Fats 19.9718457598 11836018
MESH:D007333 Insulin Resistance Estradiol 19.9716393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 19.9716306350
MESH:D007333 Insulin Resistance rosiglitazone 19.9716306350
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.558074119 9022650
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 2.9316580747
MESH:D007579 Jejunal Diseases 1-Methyl-3-isobutylxanthine 4.9818306037
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.9815604871
MESH:D007674 Kidney Diseases Acetaminophen 20.3315629191 12587719
MESH:D007674 Kidney Diseases Cyclosporine 20.338314463 10903974 18776723
MESH:D007674 Kidney Diseases Doxorubicin 20.3315699352 15369732 16775033
MESH:D007674 Kidney Diseases Estradiol 20.3315618244
MESH:D007674 Kidney Diseases sodium arsenite 20.3320008137
MESH:D007674 Kidney Diseases Tacrolimus 20.3311041285
MESH:D007676 Kidney Failure, Chronic Doxorubicin 3.7516707910
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 24.3216705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 24.3216705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 24.326582329
MESH:D007680 Kidney Neoplasms Cyclosporine 24.3212371664
MESH:D007680 Kidney Neoplasms Estradiol 24.3215610895
MESH:D007680 Kidney Neoplasms Fluorouracil 24.3216985049
MESH:D007938 Leukemia Benzene 3.1518335105 15935818 14694614 17119257
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.6916085563
MESH:D007951 Leukemia, Myeloid Benzene 3.9117506065
MESH:D015470 Leukemia, Myeloid, Acute Benzene 2.6119478238
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 4.778812269
MESH:D008103 Liver Cirrhosis Dietary Fats 9.5018296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 9.5018522880 18407596 18665156 19638242 20032147
MESH:D008103 Liver Cirrhosis Phenobarbital 9.5021047994
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.909327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 9.8316718785
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 9.8316439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 9.8314716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 9.8315474484
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 9.8315980055 17347453
MESH:D008106 Liver Cirrhosis, Experimental Sirolimus 9.8317050028
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 9.8312878042
MESH:D008107 Liver Diseases Acetaminophen 5.6819460945 16610002 19014921 12587719 12969438 16611625 19784758 11587558
MESH:D008107 Liver Diseases Diethylnitrosamine 5.6817034775
MESH:D008107 Liver Diseases Phenobarbital 5.6819363144
MESH:D017114 Liver Failure, Acute Acetaminophen 2.8417185352 16871587
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 26.347678174
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 26.3421295105 19389873
MESH:D008113 Liver Neoplasms Diethylnitrosamine 26.3420492335 19255062 20118626 20434301 19642983 19850985 18978307 19294768 16942905 21167192 9163691 20583210 19427195 19996281 10737359 20101389 2422723 18644402 15885732 20137499 19090486 21278145 19256749 19638242 2862719 18977376 19073162 18754104 19833225 15175105 19551842 12112319 20501860 19690152 21071580 19499222 20452335 19812893 21047994 12771043 19254457 20405173 19426721 18648771
MESH:D008113 Liver Neoplasms Fluorouracil 26.3418383874 17045692 15113037 16603448
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 26.3418709148 14757943
MESH:D008113 Liver Neoplasms Phenobarbital 26.3419812893 21047994 19482888 19073162 15975961 8742319
MESH:D008113 Liver Neoplasms pirinixic acid 26.3416377806 15890375 20007298
MESH:D008113 Liver Neoplasms sodium arsenite 26.3415276417 16712894
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 26.3416984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 28.162876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 28.16598648 6587162 1399818 3712494
MESH:D008114 Liver Neoplasms, Experimental Benzene 28.1612562636
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 28.1618164116
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 28.1618093689 3124819 17174075 19539802 21159647 18775883 19126423 17942915 18164116 19009564 18253720 18544905 19004024 18079962 19519916 16267830 9362446 17854601 2563599 18282651 16842330 18308698
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 28.1616842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 28.161399818 18308698 17172636 2563599 6150874
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 28.1612151625
MESH:D008171 Lung Diseases Ozone 6.4819066396 8266340
MESH:D008171 Lung Diseases sodium arsenite 6.4819095001
MESH:D017563 Lung Diseases, Interstitial Benzene 4.3514698565
MESH:D055370 Lung Injury Ozone 3.4120417186
MESH:D008175 Lung Neoplasms Benzene 11.7512562636
MESH:D008175 Lung Neoplasms Dexamethasone 11.7511195469 15824018
MESH:D008175 Lung Neoplasms Diethylnitrosamine 11.7521163286 6695378 20970405 20512841
MESH:D008175 Lung Neoplasms Doxorubicin 11.7517418594 6189445
MESH:D008175 Lung Neoplasms Fluorouracil 11.7515246190
MESH:D008175 Lung Neoplasms Ozone 11.758597069 7614698
MESH:D008175 Lung Neoplasms sodium arsenite 11.7516712894 19931552 17306315 15276417 17077188
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 11.7511884234 19555203
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.3415086387
MESH:D008223 Lymphoma Benzene 6.7517584886 17119257
MESH:D008223 Lymphoma Doxorubicin 6.7516098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.4217654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.1215621674
MESH:D015674 Mammary Neoplasms, Animal Benzene 3.9912562636
MESH:D008325 Mammary Neoplasms, Experimental Benzene 15.6711921183
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 15.6715458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 15.6711807958 16891317 11408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 15.6717203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 15.6716827153
MESH:D020149 Manganese Poisoning Estradiol 4.0219453300
MESH:D008382 Marfan Syndrome Atenolol 5.8019430350
MESH:D008545 Melanoma Doxorubicin 4.7616827129
MESH:D008545 Melanoma Sirolimus 4.7619282848
MESH:D008545 Melanoma sodium arsenite 4.7616487513 19082730
MESH:D008546 Melanoma, Experimental Acetaminophen 3.1219513568
MESH:D008654 Mesothelioma Doxorubicin 2.8717638057
MESH:D024821 Metabolic Syndrome X rosiglitazone 4.0017261469
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.3216801185
MESH:D008679 Metaplasia Ozone 4.6410496685
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.0915792986
MESH:D009062 Mouth Neoplasms Fluorouracil 7.9316757204 18986760
MESH:D009062 Mouth Neoplasms Sirolimus 7.9319435901
MESH:D052016 Mucositis Doxorubicin 4.3417415656
MESH:D009101 Multiple Myeloma Benzene 6.5517119195
MESH:D009101 Multiple Myeloma Dexamethasone 6.5515867202 16118317 15744524
MESH:D009135 Muscular Diseases pirinixic acid 3.0616239165
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 3.279809623
MESH:D009203 Myocardial Infarction Doxorubicin 5.0319429709 15857846
MESH:D009203 Myocardial Infarction pirinixic acid 5.0319151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.6612213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 7.0916810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 7.0916411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.0217484760
MESH:D009336 Necrosis 2,4-dinitrotoluene 8.8418551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 8.8418551238 7678174
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 8.353581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 8.359029167 3581430
MESH:D009362 Neoplasm Metastasis Doxorubicin 8.3518259882
MESH:D009369 Neoplasms Fluorouracil 6.8718239605 18600527 16928823
MESH:D009369 Neoplasms pirinixic acid 6.8717405874
MESH:D009369 Neoplasms sodium arsenite 6.8711559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.2320056578
MESH:D009389 Neovascularization, Pathologic Estradiol 3.2817289903
MESH:D009401 Nephrosis Doxorubicin 4.3216636307 16899518
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.9817954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 8.0318481113 19348381
MESH:D009404 Nephrotic Syndrome Doxorubicin 8.0315640375 16889571
MESH:D009410 Nerve Degeneration Paraquat 3.3716893418
MESH:D009421 Nervous System Malformations bisphenol A 13.8611399458 16427766
MESH:D009421 Nervous System Malformations Estradiol 13.8611399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 13.8614600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 10.456679447
MESH:D009436 Neural Tube Defects Benzene 10.4515643154
MESH:D009436 Neural Tube Defects sodium arsenite 10.4512854658
MESH:D009447 Neuroblastoma Doxorubicin 3.0215555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 12.0718514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 12.0720387270
MESH:D019636 Neurodegenerative Diseases Tacrolimus 12.0715081597
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.6520387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.1316436463
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 4.519802331
MESH:D009765 Obesity Dietary Fats 3.9920132043 17217161 19632207 21332399 18457598 20518802 16723640 11836018 18674790
MESH:D009765 Obesity pirinixic acid 3.9920558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 18.3616049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 18.3616049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 18.366482804 4026338
MESH:D009784 Occupational Diseases Benzene 18.3617119257 17479406 15727169 17178637 15913788 15612468 15935809 15576619 16737584
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.553988306
MESH:D010018 Osteomalacia Phenobarbital 3.9117016548
MESH:D012516 Osteosarcoma Doxorubicin 3.7515930896
MESH:D010049 Ovarian Diseases bisphenol A 4.5311985600
MESH:D010051 Ovarian Neoplasms Benzene 16.7512562636
MESH:D010051 Ovarian Neoplasms CD 437 16.7517474084
MESH:D010051 Ovarian Neoplasms Estradiol 16.7519401270
MESH:D010051 Ovarian Neoplasms Mifepristone 16.7516525653
MESH:D010051 Ovarian Neoplasms Progesterone 16.7516525653 17393432
MESH:D010051 Ovarian Neoplasms sodium arsenite 16.7517306315 15276417
MESH:D010146 Pain Acetaminophen 2.0416870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 7.5716540662
MESH:D010190 Pancreatic Neoplasms Fluorouracil 7.5715113037 19003803 16929163 16500647
MESH:D010190 Pancreatic Neoplasms Phenobarbital 7.5716965848
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.047296757
MESH:D010300 Parkinson Disease Paraquat 5.2415451049 11181820 11445065 16510128 12911755 16140633 11124998 15824117
MESH:D010300 Parkinson Disease Sirolimus 5.2419682553
MESH:D010302 Parkinson Disease, Secondary Paraquat 3.9916190885
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.7812520081
MESH:D010538 Peritonitis Ozone 3.6916369182
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.016228378
MESH:D003557 Phyllodes Tumor Doxorubicin 4.6917983394
MESH:D010997 Pleural Neoplasms Doxorubicin 4.6917638057
MESH:D011014 Pneumonia Ozone 9.5518381685 18007984 18929643
MESH:D011014 Pneumonia Paraquat 9.5512504350
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.1318163543
MESH:D011230 Precancerous Conditions Cyclosporine 13.0612371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 13.062563599
MESH:D011230 Precancerous Conditions Phenobarbital 13.062563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.2821297632
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 13.6910548101
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 13.6917132714
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 13.6911222880 11118676 11399792 11896295
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 9.2020887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 9.2020887781
MESH:D011471 Prostatic Neoplasms bisphenol A 1.8716740699
MESH:D011471 Prostatic Neoplasms Doxorubicin 1.8716868541 16729912 15897917 15749863 16888761 18437689
MESH:D011471 Prostatic Neoplasms Estradiol 1.8716740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 1.8719082440 18626508
MESH:D011471 Prostatic Neoplasms methylselenic acid 1.8716205645
MESH:D011471 Prostatic Neoplasms sodium arsenite 1.8716039940
MESH:D019310 Pseudolymphoma Phenobarbital 4.0312752131
MESH:D011565 Psoriasis Cyclosporine 2.0616882103
MESH:D011629 Puberty, Precocious bisphenol A 4.3310548101
MESH:D011658 Pulmonary Fibrosis Paraquat 2.7317997886 16324872
MESH:D012004 Rectal Neoplasms Fluorouracil 3.6318722050 18286688 15538739 16160472
MESH:D051437 Renal Insufficiency Doxorubicin 3.7817922066
MESH:D015427 Reperfusion Injury pirinixic acid 2.1519058328
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 7.8818379247 11700416
MESH:D012128 Respiratory Distress Syndrome, Adult Paraquat 7.8811700416
MESH:D012135 Respiratory Sounds Paraquat 3.6211874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.4118990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 7.783692021
MESH:D012162 Retinal Degeneration Paraquat 7.7816458197
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.6818045962
MESH:D012509 Sarcoma Doxorubicin 3.6016767912 15675481 17710206 15625365 17203757 18313854
MESH:D012512 Sarcoma, Ewing's Doxorubicin 3.8116326096 14601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.3417846226
MESH:D012640 Seizures 2,4-dinitrotoluene 7.9918551238
MESH:D012640 Seizures 2,6-dinitrotoluene 7.9918551238
MESH:D012640 Seizures Phenobarbital 7.993137016 11442880 4039156 16876388
MESH:D003294 Seizures, Febrile Phenobarbital 4.376407741
MESH:D012878 Skin Neoplasms Doxorubicin 8.1415692506
MESH:D012878 Skin Neoplasms sodium arsenite 8.1418572023 19524636
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 8.1416192470
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.1215625365 17203757 16767912
MESH:D013119 Spinal Cord Injuries Progesterone 3.8316503802 15862959
MESH:D016135 Spinal Dysraphism sodium arsenite 3.4412854658
MESH:D013272 Stomach Diseases Dexamethasone 3.8715472012
MESH:D013274 Stomach Neoplasms Benzene 3.1812562636
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.1818456281
MESH:D013274 Stomach Neoplasms Fluorouracil 3.1818567086 17172411 15786421 18396642 17498489 17522103 19084572 16424979 19015929 16951190
MESH:D013276 Stomach Ulcer Dexamethasone 3.1015138204
MESH:D019966 Substance-Related Disorders bisphenol A 3.5316684133 16045194
MESH:D013953 Thymus Neoplasms Benzene 4.5010850423
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.4412697716
MESH:D018382 Thyroid Hormone Resistance Syndrome Atenolol 5.959349583
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 14.267505956 6582329 6587162 3712494 1399818
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 14.267505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 14.2617909728 16010429
MESH:D013964 Thyroid Neoplasms Phenobarbital 14.261399818
MESH:D013978 Tibial Fractures Estradiol 4.2219048282
MESH:D014062 Tongue Neoplasms Fluorouracil 3.6016280240
MESH:D014402 Tuberous Sclerosis Sirolimus 5.1421115397 18495876
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 17.3316049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 17.3316049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 17.338074119
MESH:D001749 Urinary Bladder Neoplasms CD 437 17.3316720286
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 17.3317653716
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 17.3317306315 16452187 16712894 11723127
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 10.4810091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 10.4810091137
MESH:D014581 Urticaria Acetaminophen 2.5610982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 8.1816803524
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 8.1811813266
MESH:D014591 Uterine Diseases bisphenol A 4.5414652134
MESH:D014594 Uterine Neoplasms Benzene 3.9012562636
MESH:D014605 Uveitis Cyclosporine 17.651336536
MESH:D014605 Uveitis Dexamethasone 17.651336536
MESH:D014605 Uveitis Sirolimus 17.651336536
MESH:D014652 Vascular Diseases sodium arsenite 3.9717056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.1312125929
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 3.7817678736 17638931 17334414 16364871
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.7815886252
MESH:D015430 Weight Gain Dietary Fats 3.3616723640
MESH:D014985 Xerophthalmia Cyclosporine 3.9817120751
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA28162
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    PA447278Depression
    PA447207Depressive Disorder
    PA447321Depressive Disorder, Major
    Releated drug ID Related drug Name
    PA452229antidepressants
    PA449015citalopram
    PA449233desipramine
    PA449673fluoxetine
    PA450522mirtazapine
    PA451866venlafaxine
    PA451096prednisolone
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


    Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved