AutismKB 2.0

Annotation Detail for ZNF365


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Basic Information Top
Gene Symbol:ZNF365 ( KIAA0844,MGC41821,MGC87345,Su48,UAN,ZNF365D )
Gene Full Name: zinc finger protein 365
Band: 10q21.2
Quick LinksEntrez ID:22891; OMIM: 607818; Uniprot ID:TALAN_HUMAN; ENSEMBL ID: ENSG00000138311; HGNC ID: 18194
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
No data
Desease Name
CHEMDEPENDENCY
IMMUNE
smoking cessation
Crohn's disease
Desease Name
Crohn's disease
Breast cancer
Desease Name
Nephrolithiasis, uric acid, susceptibility to
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of ZNF365 mRNAaffects cotreatment|decreases expression 19619570
D004958 Estradiol Estradiol results in increased expression of ZNF365 mRNAincreases expression 19619570
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of ZNF365 mRNAaffects cotreatment|decreases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of ZNF365 mRNAdecreases expression 19619570
D014635 Valproic Acid Valproic Acid results in increased expression of ZNF365 mRNAincreases expression 19101580
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 10.9211752688 15322242 14514962
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 10.928875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 4.4119490988
MESH:D000230 Adenocarcinoma Estradiol 2.1811473722
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 4.1216835633
MESH:D000550 Amblyopia Valproic Acid 6.1017688650
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.3911748828
MESH:D001008 Anxiety Disorders Valproic Acid 3.9417497229
MESH:D001321 Autistic Disorder Valproic Acid 1.9816609825 15238991 18940202 19460635 20603192 17688650 18396377 18985861 18177632 18558336 18775368 17507914 19232924 17157402 18316065
MESH:D001714 Bipolar Disorder Valproic Acid 3.2617594078 20046352
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.5312125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.6615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 8.8915746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 8.898888407
MESH:D001943 Breast Neoplasms marker/mechanism 21278746
MESH:D001943 Breast Neoplasms Estradiol 1.9017289903 18497071 14630087 12948864 17261762 16675129 17018787 19861407
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9020435547
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 5.2116111702
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 3.1616835633
MESH:D006528 Carcinoma, Hepatocellular Estradiol 1.7916924424
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.5818850075 16120746 18670907
MESH:D002471 Cell Transformation, Neoplastic Estradiol 3.0618566989
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.8320734317
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.5816835633
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.2516354765 15340226 15668235 12621046 8697196
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.4814669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.5710048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Valproic Acid 2.578888407 17688650 16575769
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.7417107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.8319279558
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 4.1120420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 4.1119641884 1733752
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 3.0911462148
MESH:D004421 Dystonia Valproic Acid 4.581851702
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.8511000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.7715322242 16714409 18230668
MESH:D016889 Endometrial Neoplasms Estradiol 3.2511473722 18566989 19148513
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.4710568697 9294722
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.813659116 17275665
MESH:D004828 Epilepsies, Partial Valproic Acid 4.7816628512 3922381
MESH:D004827 Epilepsy Valproic Acid 3.1218234410 20417680
MESH:D004832 Epilepsy, Absence Valproic Acid 4.007562514 6426943 6254150
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.957750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.813659116
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.3411564622
MESH:D005234 Fatty Liver Valproic Acid 3.7819224547 14986274
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 4.1111858732
MESH:D005315 Fetal Diseases Valproic Acid 5.7516575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.7118558336 8888407
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 3.6020067830
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 5.4610696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.5311294989 10048152
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.8211000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.5416120746 15340226 12621046
MESH:D006558 Herpes Genitalis Estradiol 5.9015709030
MESH:D019584 Hot Flashes Estradiol 4.6217088409
MESH:D006849 Hydrocephalus Valproic Acid 5.6117688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.9115340226 8697196 18606429 16354765 16959395
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 2.0318850075 18670907
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 2.0412200463 12878042
MESH:D007333 Insulin Resistance Estradiol 3.2316627594 16393666
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.8216580747
MESH:D007674 Kidney Diseases Estradiol 2.8015618244
MESH:D007680 Kidney Neoplasms Estradiol 3.3615610895
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.2017596541 16294345
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 2.3614716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 2.3612878042
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 1.8416984957
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 2.3512151625
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 5.1317228818
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 1.2411884234 19555203
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.8217203775 11807958 11408345 16891317
MESH:D020149 Manganese Poisoning Estradiol 5.3519453300
MESH:D008881 Migraine Disorders Valproic Acid 3.5018765137 18803445
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.518888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.3717596541
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.3812213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.6216810080
MESH:D009389 Neovascularization, Pathologic Estradiol 4.4717289903
OMIM:605990 NEPHROLITHIASIS, URIC ACID, SUSCEPTIBILITY TO marker/mechanism
MESH:D009421 Nervous System Malformations Estradiol 11.4811399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 11.4814600291
MESH:D009436 Neural Tube Defects Valproic Acid 3.3916359493 8888407
MESH:D010051 Ovarian Neoplasms Estradiol 2.3219401270
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 5.1212520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 4.1418163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 12.0711896295 11222880 11118676 11399792
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 12.0720603192
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 4.3720887781
MESH:D011471 Prostatic Neoplasms Estradiol 3.0216740699
MESH:D019310 Pseudolymphoma Valproic Acid 5.4111422049 12752131
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.4218990726
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.7019155313
MESH:D012559 Schizophrenia Valproic Acid 2.1119110320 15737665
MESH:D012640 Seizures Valproic Acid 3.023137016 15475178 11044598 16876388 1511512 14763951 11738929 17978042
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.2116192470
MESH:D016135 Spinal Dysraphism Valproic Acid 4.1319490988
MESH:D013226 Status Epilepticus Valproic Acid 5.4112833885
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.7712697716
MESH:D013978 Tibial Fractures Estradiol 5.5519048282
MESH:D014178 Translocation, Genetic Valproic Acid 6.1017262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 5.263119515
MESH:D014564 Urogenital Abnormalities Valproic Acid 5.308888407
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 5.4612125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 5.1215886252
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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