AutismKB 2.0

Annotation Detail for RPH3A


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Basic Information Top
Gene Symbol:RPH3A ( KIAA0985 )
Gene Full Name: rabphilin 3A homolog (mouse)
Band: 12q24.13
Quick LinksEntrez ID:22895; OMIM: 612159; Uniprot ID:RP3A_HUMAN; ENSEMBL ID: ENSG00000089169; HGNC ID: 17056
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of RPH3A mRNAaffects expression 16483693
D001205 Ascorbic Acid Ascorbic Acid results in increased expression of RPH3A mRNAincreases expression 15305145
C006780 bisphenol A bisphenol A results in increased expression of RPH3A mRNAincreases expression 17010207
C055494 caffeic acid phenethyl ester [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of RPH3A mRNAaffects cotreatment|decreases expression 20360939
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of RPH3A mRNAaffects cotreatment|decreases expression 20360939
D019833 Genistein Genistein results in increased expression of RPH3A mRNAincreases expression 17010207
C025256 nonylphenol nonylphenol results in increased expression of RPH3A mRNAincreases expression 17010207
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 3.9518287403
MESH:D000230 Adenocarcinoma Genistein 2.5311473722
MESH:D000236 Adenoma Diethylnitrosamine 2.996695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 4.3017620307 19061943 17162532 16434500 18056438 19052882
MESH:D001862 Bone Resorption bisphenol A 4.1411985600
MESH:D001943 Breast Neoplasms Ascorbic Acid 2.0616443354
MESH:D001943 Breast Neoplasms bisphenol A 2.0617123778
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.0617474063
MESH:D001943 Breast Neoplasms Genistein 2.0616541309 17200150 16873071
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 3.2419383236 16878318 19519916 17173139 21159647 16288022 18494052 10672840 18691550 18971187 18056438 20514400 19394651 17055752 19822196 16502159 19418558 16569478 19335982 16698587 18210153 16830150 10737359 20727157 17428255 19171122 19107877 18506893 20432363 17978847 20524982 16935385 18785209 19539802 20007298 17138121 20101231 18978308 3084413 16540662 19701751 17761372 20935162 20214788 11831363 19208518 18393292 16328049 19052882 18788625 20512989 19919837 16779866 16807293 3581430 20084675 18665156 16681979 17162532
MESH:D006528 Carcinoma, Hepatocellular Genistein 3.2416924424
MESH:D002278 Carcinoma in Situ bisphenol A 5.3817123778
MESH:D002318 Cardiovascular Diseases Genistein 3.4816332659
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 3.042727394 21159647 17174075 7505956
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 3.9319052882
MESH:D003110 Colonic Neoplasms Genistein 2.3217182828
MESH:D003139 Common Cold Ascorbic Acid 5.9217323712
MESH:D003924 Diabetes Mellitus, Type 2 Ascorbic Acid 7.6316506275
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 7.6320387270
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 7.6316647724
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 2.1219107877
MESH:C538011 Eales disease Ascorbic Acid 5.929068938
MESH:D004714 Endometrial Hyperplasia Genistein 4.9916402032
MESH:D016889 Endometrial Neoplasms Genistein 3.5311473722
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.5616302075
MESH:D005234 Fatty Liver Diethylnitrosamine 3.4620387270 21071580
MESH:D005909 Glioblastoma Genistein 3.4316598420
MESH:D006330 Heart Defects, Congenital Ascorbic Acid 3.8916080930
MESH:D006548 Hernia, Diaphragmatic Ascorbic Acid 3.5516863852 16490937
MESH:D007249 Inflammation Diethylnitrosamine 2.5018785209
MESH:D007333 Insulin Resistance bisphenol A 3.4616393666
MESH:D007414 Intestinal Neoplasms caffeic acid phenethyl ester 4.8510783313
MESH:D007674 Kidney Diseases caffeic acid phenethyl ester 3.6915369732
MESH:D007938 Leukemia Genistein 3.1418980019 17468513
MESH:D015473 Leukemia, Promyelocytic, Acute caffeic acid phenethyl ester 4.1616766008
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.9618407596 18522880 19638242 18665156 20032147
MESH:D008106 Liver Cirrhosis, Experimental Genistein 2.0617823541
MESH:D008107 Liver Diseases Diethylnitrosamine 2.1517034775
MESH:D008113 Liver Neoplasms Diethylnitrosamine 2.322422723 18644402 19812893 20501860 19642983 21047994 19996281 20405173 18977376 19073162 18648771 18978307 20101389 20118626 20583210 20492335 19255062 19256749 12112319 18754104 21071580 19426721 19254457 9163691 20452335 20434301 21278145 15885732 21167192 19427195 19499222 19850985 2862719 16942905 19638242 10737359 19090486 19551842 19294768 19833225 19690152 12771043 15175105 20137499
MESH:D008114 Liver Neoplasms, Experimental Ascorbic Acid 6.8318544905
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 6.8319539802 18253720 19519916 21159647 18775883 3124819 9362446 2563599 16842330 18164116 18544905 18093689 18079962 19126423 18308698 17854601 19009564 17942915 16267830 17174075 18282651 19004024
MESH:D008171 Lung Diseases Ascorbic Acid 4.1216863852
MESH:D008175 Lung Neoplasms Ascorbic Acid 2.8516401635
MESH:D008175 Lung Neoplasms Diethylnitrosamine 2.8521163286 20970405 6695378 20512841
MESH:D008325 Mammary Neoplasms, Experimental Genistein 3.1012929590 14578162
MESH:D009203 Myocardial Infarction Genistein 2.9517141266
MESH:D015428 Myocardial Reperfusion Injury Genistein 3.8717141266
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.663581430 9029167
MESH:D009421 Nervous System Malformations bisphenol A 11.0011399458 16427766
MESH:D009421 Nervous System Malformations Genistein 11.0016427766
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.5720387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.5620387270
MESH:D009765 Obesity Ascorbic Acid 3.1917217161
MESH:D010024 Osteoporosis Genistein 3.4119401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 4.3916169203
MESH:D010049 Ovarian Diseases bisphenol A 5.3811985600
MESH:D010051 Ovarian Neoplasms Genistein 2.6719005980
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.5016540662
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.802563599
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 4.3510548101
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 4.4920887781
MESH:D011471 Prostatic Neoplasms bisphenol A 3.3516740699
MESH:D011471 Prostatic Neoplasms Genistein 3.3515256057 15378649 16925846
MESH:D011629 Puberty, Precocious bisphenol A 5.1810548101
MESH:D011657 Pulmonary Eosinophilia Ascorbic Acid 5.7814606601
MESH:D012174 Retinitis Pigmentosa Ascorbic Acid 3.3716849425
MESH:D012871 Skin Diseases Ascorbic Acid 3.2718709164
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 1.7618456281
MESH:D013276 Stomach Ulcer Ascorbic Acid 4.1718726076
MESH:D020521 Stroke Ascorbic Acid 4.5116517955 16403987
MESH:D019966 Substance-Related Disorders bisphenol A 4.3816684133 16045194
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 3.197505956
MESH:D014591 Uterine Diseases bisphenol A 5.4514652134
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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