Annotation Detail for FOXG1
Basic Information
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| Gene Symbol: | FOXG1 ( BF1,BF2,FHKL3,FKH2,FKHL1,FKHL2,FKHL3,FKHL4,FOXG1A,FOXG1B,FOXG1C,HBF-1,HBF-2,HBF-3,HBF-G2,HBF2,HFK1,HFK2,HFK3,KHL2,QIN ) |
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| Gene Full Name: | forkhead box G1 |
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| Band: | 14q12 |
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| Quick Links | Entrez ID:2290; OMIM: 164874; Uniprot ID:FOXG1_HUMAN; ENSEMBL ID: ENSG00000176165; HGNC ID: 3811 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
|---|
| 200002 | Regulation of nuclear SMAD2/3 signaling |
| Desease ID | Desease Name |
|---|
| 1860 | Brain tumor |
| 2047 | Rett syndrome |
| Desease Name |
|---|
| Multiple sclerosis--Brain Glutamate Concentrations |
| Desease Name |
|---|
| Rett syndrome, congenital variant |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D003913 |
Dextroamphetamine |
Dextroamphetamine results in increased expression of FOXG1 mRNA | increases expression | 12558987
|
| D005419 |
Flavonoids |
Flavonoids results in increased expression of FOXG1 mRNA | increases expression | 18035473
|
| D009151 |
Mustard Gas |
Mustard Gas results in increased expression of FOXG1 mRNA | increases expression | 15674843
|
| C009166 |
retinol acetate |
retinol acetate results in increased expression of FOXG1 mRNA | increases expression | 16772331
|
| D013749 |
Tetrachlorodibenzodioxin |
Tetrachlorodibenzodioxin results in decreased expression of FOXG1 mRNA | decreases expression | 19933214
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
Tetrachlorodibenzodioxin |
3.38 | 14514962 11752688 15322242 |
| MESH:D055673 |
Acrocallosal Syndrome |
marker/mechanism |
|
| 18627055 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
Tetrachlorodibenzodioxin |
3.92 | 16835633 |
| MESH:D000740 |
Anemia |
|
Tetrachlorodibenzodioxin |
3.29 | 11748828 |
| MESH:D001249 |
Asthma |
|
Mustard Gas |
2.79 | 10378619 |
| MESH:D001768 |
Blister |
|
Mustard Gas |
5.70 | 19167455 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
Tetrachlorodibenzodioxin |
3.42 | 12125929 |
| MESH:D001836 |
Body Weight Changes |
|
Tetrachlorodibenzodioxin |
4.40 | 15340226 |
| MESH:D001848 |
Bone Diseases, Developmental |
|
Tetrachlorodibenzodioxin |
2.97 | 15746008 |
| MESH:D001943 |
Breast Neoplasms |
|
Tetrachlorodibenzodioxin |
1.67 | 20435547 |
| MESH:D001989 |
Bronchiolitis Obliterans |
|
Mustard Gas |
5.70 | 15286001 |
| MESH:D029481 |
Bronchitis, Chronic |
|
Mustard Gas |
5.59 | 17687719 10378619 |
| MESH:D002277 |
Carcinoma |
|
Tetrachlorodibenzodioxin |
3.09 | 16835633 |
| MESH:D006332 |
Cardiomegaly |
|
Tetrachlorodibenzodioxin |
2.54 | 18670907 16120746 18850075 |
| MESH:D018281 |
Cholangiocarcinoma |
|
Tetrachlorodibenzodioxin |
3.49 | 16835633 |
| MESH:D002972 |
Cleft Palate |
|
Tetrachlorodibenzodioxin |
2.22 | 12621046 8697196 15668235 15340226 16354765 |
| MESH:D000013 |
Congenital Abnormalities |
|
Tetrachlorodibenzodioxin |
3.38 | 14669216 17141729 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Tetrachlorodibenzodioxin |
1.27 | 10048152 15322242 20055451 |
| MESH:D003924 |
Diabetes Mellitus, Type 2 |
|
Tetrachlorodibenzodioxin |
1.73 | 17107852 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Tetrachlorodibenzodioxin |
1.61 | 20420201 |
| MESH:D004362 |
Drug Toxicity |
|
Tetrachlorodibenzodioxin |
3.02 | 11462148 |
| MESH:D004487 |
Edema |
|
Mustard Gas |
8.10 | 11402378 9260866 11428631 11428647 |
| MESH:D004487 |
Edema |
|
Tetrachlorodibenzodioxin |
8.10 | 11000095 12711302 |
| MESH:D004489 |
Edema, Cardiac |
|
Tetrachlorodibenzodioxin |
4.51 | 16714409 18230668 15322242 |
| MESH:D004715 |
Endometriosis |
|
Tetrachlorodibenzodioxin |
3.37 | 10568697 9294722 |
| MESH:D004890 |
Erythema |
|
Mustard Gas |
5.70 | 9357497 |
| MESH:D005124 |
Eye Abnormalities |
|
Tetrachlorodibenzodioxin |
3.27 | 11564622 |
| MESH:D005313 |
Fetal Death |
|
Tetrachlorodibenzodioxin |
3.94 | 11858732 |
| MESH:D005355 |
Fibrosis |
|
Tetrachlorodibenzodioxin |
3.43 | 20067830 |
| MESH:D006058 |
Gonadal Disorders |
|
Tetrachlorodibenzodioxin |
5.21 | 10696789 |
| MESH:D006330 |
Heart Defects, Congenital |
|
Tetrachlorodibenzodioxin |
2.49 | 10048152 11294989 |
| MESH:D006470 |
Hemorrhage |
|
Tetrachlorodibenzodioxin |
3.71 | 11000095 |
| MESH:D006529 |
Hepatomegaly |
|
Tetrachlorodibenzodioxin |
3.37 | 15340226 16120746 12621046 |
| MESH:D006869 |
Hydronephrosis |
|
Tetrachlorodibenzodioxin |
4.66 | 15340226 16959395 8697196 18606429 16354765 |
| MESH:D006973 |
Hypertension |
|
Tetrachlorodibenzodioxin |
2.01 | 18850075 18670907 |
| MESH:D007249 |
Inflammation |
|
Flavonoids |
9.33 | 17296493 |
| MESH:D007249 |
Inflammation |
|
Mustard Gas |
9.33 | 16001271 17524151 9357497 8975870 11428647 11428620 11402378 9260866 11428631 |
| MESH:D007249 |
Inflammation |
|
Tetrachlorodibenzodioxin |
9.33 | 12200463 12878042 |
| MESH:D007569 |
Jaw Abnormalities |
|
Tetrachlorodibenzodioxin |
3.71 | 16580747 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Tetrachlorodibenzodioxin |
1.25 | 12878042 |
| MESH:D008113 |
Liver Neoplasms |
|
Tetrachlorodibenzodioxin |
1.82 | 16984957 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
Tetrachlorodibenzodioxin |
2.31 | 12151625 |
| MESH:D008171 |
Lung Diseases |
|
Mustard Gas |
3.67 | 18702808 18161513 |
| MESH:D008175 |
Lung Neoplasms |
|
Mustard Gas |
2.49 | 8781369 3148597 |
| MESH:D008175 |
Lung Neoplasms |
|
Tetrachlorodibenzodioxin |
2.49 | 19555203 11884234 |
| MESH:D008607 |
Mental Retardation |
marker/mechanism |
|
| 18627055 |
| MESH:D008831 |
Microcephaly |
marker/mechanism |
|
| 18627055 |
| MESH:D009041 |
Motion Sickness |
|
Dextroamphetamine |
6.13 | 1613127 |
| MESH:D017202 |
Myocardial Ischemia |
|
Tetrachlorodibenzodioxin |
3.31 | 12213967 |
| MESH:D009421 |
Nervous System Malformations |
|
Tetrachlorodibenzodioxin |
3.65 | 14600291 |
| MESH:D009503 |
Neutropenia |
|
Mustard Gas |
4.37 | 7688884 16761898 |
| MESH:D010382 |
Peliosis Hepatis |
|
Tetrachlorodibenzodioxin |
4.86 | 12520081 |
| MESH:D011041 |
Poisoning |
|
Mustard Gas |
4.20 | 15727166 |
| MESH:D017119 |
Porphyria Cutanea Tarda |
|
Tetrachlorodibenzodioxin |
4.00 | 18163543 |
| MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
Tetrachlorodibenzodioxin |
3.73 | 11118676 11896295 11222880 11399792 |
| MESH:D011537 |
Pruritus |
|
Mustard Gas |
4.63 | 18058305 |
| MESH:D011658 |
Pulmonary Fibrosis |
|
Mustard Gas |
3.03 | 10334151 17894541 17720292 17266442 17620002 |
| MESH:D015619 |
Respiratory System Abnormalities |
|
Tetrachlorodibenzodioxin |
4.28 | 18990726 |
| OMIM:613454 |
RETT SYNDROME, CONGENITAL VARIANT |
marker/mechanism |
|
| |
| MESH:D012640 |
Seizures |
marker/mechanism |
|
| 18627055 |
| MESH:D012871 |
Skin Diseases |
|
Mustard Gas |
2.78 | 15451306 12880345 16961503 |
| MESH:D012878 |
Skin Neoplasms |
|
Tetrachlorodibenzodioxin |
2.18 | 16192470 |
| MESH:D013959 |
Thyroid Diseases |
|
Tetrachlorodibenzodioxin |
4.51 | 12697716 |
| MESH:D054079 |
Vascular Malformations |
|
Tetrachlorodibenzodioxin |
5.21 | 12125929 |
| MESH:D019282 |
Wasting Syndrome |
|
Tetrachlorodibenzodioxin |
4.86 | 15886252 |
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