AutismKB 2.0

Annotation Detail for DKK1


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Basic Information Top
Gene Symbol:DKK1 ( DKK-1,SK )
Gene Full Name: dickkopf homolog 1 (Xenopus laevis)
Band: 10q21.1
Quick LinksEntrez ID:22943; OMIM: 605189; Uniprot ID:DKK1_HUMAN; ENSEMBL ID: ENSG00000107984; HGNC ID: 2891
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04310Wnt signaling pathway
No data
Pathway IDPathway Name
200171Validated targets of C-MYC transcriptional repression
200106Regulation of Wnt-mediated beta catenin signaling and target gene transcription
200101Direct p53 effectors
200052Presenilin action in Notch and Wnt signaling
200055Wnt signaling network
Pathway IDPathway Name
P00057Wnt signaling pathway
No data
Related Diseases/Disorders Top
No data
No data
No data
Desease Name
Electrocardiographic traits
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C063002 2,3-dimethoxy-1,4-naphthoquinone 2,3-dimethoxy-1,4-naphthoquinone results in increased expression of DKK1 mRNAincreases expression 17547211
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of DKK1 proteinaffects expression 20106945
C006632 arsenic trioxide arsenic trioxide results in increased expression of DKK1 mRNAincreases expression 17547211
D019324 beta-Naphthoflavone beta-Naphthoflavone results in decreased expression of DKK1 mRNAdecreases expression 19737606
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of DKK1 mRNAdecreases expression 20106945
C095105 bexarotene bexarotene results in increased expression of DKK1 mRNAincreases expression 17178900
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of DKK1 mRNAincreases expression 15336504
12414654
D002104 Cadmium Cadmium results in increased expression of DKK1 mRNAincreases expression 21172416
D004390 Chlorpyrifos Chlorpyrifos results in increased expression of DKK1 mRNAincreases expression 18502319
D002994 Clofibrate PPARA protein affects the reaction [Clofibrate results in decreased expression of DKK1 mRNA]affects reaction|decreases expression 17585979
D016572 Cyclosporine Cyclosporine results in decreased expression of DKK1 mRNAdecreases expression 20106945
C014347 decitabine [decitabine affects the methylation of DKK1 promoter] which affects the expression of DKK1 mRNAaffects expression|affects methylation 18283316
C014347 decitabine decitabine results in decreased methylation of DKK1 promoterdecreases methylation 19387464
C014347 decitabine decitabine results in increased expression of DKK1 mRNAincreases expression 19387464
17785578
D003976 Diazinon Diazinon results in increased expression of DKK1 mRNAincreases expression 18502319
D002945 Cisplatin DKK1 protein affects the susceptibility to Cisplatinaffects response to substance 16217747
D004178 Diquat Diquat results in increased expression of DKK1 mRNAincreases expression 21172416
D004317 Doxorubicin DKK1 protein affects the susceptibility to Doxorubicinaffects response to substance 16217747
D004958 Estradiol Estradiol results in decreased expression of DKK1 mRNAdecreases expression 20106945
D004958 Estradiol [Progesterone co-treated with Estradiol] results in increased expression of DKK1 mRNAaffects cotreatment|increases expression 17404688
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of DKK1 mRNAaffects expression 17555576
D005472 Fluorouracil DKK1 protein affects the susceptibility to Fluorouracilaffects response to substance 16217747
15352031
D005472 Fluorouracil Fluorouracil results in decreased expression of DKK1 proteindecreases expression 15352031
D005492 Folic Acid Folic Acid affects the expression of DKK1 mRNAaffects expression 17320366
D005492 Folic Acid Folic Acid results in increased expression of DKK1 mRNAincreases expression 17868486
D006861 Hydrogen Peroxide Hydrogen Peroxide results in increased expression of DKK1 mRNAincreases expression 12414654
D008070 Lipopolysaccharides Lipopolysaccharides results in decreased expression of DKK1 mRNAdecreases expression 12057914
D008727 Methotrexate Methotrexate results in decreased expression of DKK1 mRNAdecreases expression 17320366
D008727 Methotrexate Methotrexate results in decreased expression of DKK1 mRNAdecreases expression 17320366
D015735 Mifepristone Mifepristone inhibits the reaction [Progesterone results in increased expression of DKK1 mRNA]decreases reaction|increases expression 16449346
D015735 Mifepristone Mifepristone inhibits the reaction [Progesterone results in increased expression of DKK1 protein]decreases reaction|increases expression 16449346
D009532 Nickel Nickel results in decreased expression of DKK1 mRNAdecreases expression 19130878
C022838 nickel chloride nickel chloride results in increased expression of DKK1 mRNAincreases expression 17547211
D011374 Progesterone Mifepristone inhibits the reaction [Progesterone results in increased expression of DKK1 mRNA]decreases reaction|increases expression 16449346
D011374 Progesterone Mifepristone inhibits the reaction [Progesterone results in increased expression of DKK1 protein]decreases reaction|increases expression 16449346
D011374 Progesterone [Progesterone co-treated with Estradiol] results in increased expression of DKK1 mRNAaffects cotreatment|increases expression 17404688
D011374 Progesterone Progesterone results in increased expression of DKK1 mRNAincreases expression 17404688
16449346
D011374 Progesterone Progesterone results in increased expression of DKK1 proteinincreases expression 16449346
D011374 Progesterone Progesterone results in decreased expression of DKK1decreases expression 17510236
C093642 SB 203580 SB 203580 inhibits the reaction [BMP5 protein results in increased expression of DKK1 mRNA]decreases reaction|increases expression 15242789
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of DKK1 mRNAdecreases expression 20106945
D014212 Tretinoin DKK1 protein promotes the reaction [Tretinoin results in increased expression of DLX2 protein]increases expression|increases reaction 17064353
D014212 Tretinoin DKK1 protein promotes the reaction [Tretinoin results in increased expression of TUBB3 protein]increases expression|increases reaction 17064353
D014212 Tretinoin Tretinoin results in increased expression of DKK1 mRNAincreases expression 17064353
D014212 Tretinoin Tretinoin results in increased expression of DKK1 proteinincreases expression 17064353
C113580 U 0126 U 0126 results in decreased expression of DKK1 mRNAdecreases expression 17320366
C113580 U 0126 U 0126 results in decreased expression of DKK1 mRNAdecreases expression 17320366
D014747 Vinblastine DKK1 protein affects the susceptibility to Vinblastineaffects response to substance 16217747
D024483 Vitamin K 3 Vitamin K 3 results in increased expression of DKK1 mRNAincreases expression 12414654
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Methotrexate 7.5112039119
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.5115322242 11752688 14514962
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.6117505938
MESH:D000168 Acrocephalosyndactylia U 0126 5.1517694057
MESH:D058186 Acute Kidney Injury Cisplatin 8.1015814532 17670903 12690470
MESH:D058186 Acute Kidney Injury Folic Acid 8.1016316344 17003819 16595132
MESH:D055371 Acute Lung Injury Lipopolysaccharides 8.5918653653 11850527
MESH:D055371 Acute Lung Injury Nickel 8.5916166738
MESH:D000230 Adenocarcinoma arsenic trioxide 19.5019825857 11798837
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 19.5020127859 20464547
MESH:D000230 Adenocarcinoma Cisplatin 19.5011798837 17638652
MESH:D000230 Adenocarcinoma Doxorubicin 19.5017418594
MESH:D000230 Adenocarcinoma Estradiol 19.5011473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 19.5014692618
MESH:D000230 Adenocarcinoma Fluorouracil 19.5017638652
MESH:D000236 Adenoma Benzo(a)pyrene 10.236695378
MESH:D000236 Adenoma beta-Naphthoflavone 10.2319389873
MESH:D000236 Adenoma Folic Acid 10.2316963246
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.0516835633
MESH:D000382 Agricultural Workers' Diseases Chlorpyrifos 8.0917119214 11874814 16611668
MESH:D000382 Agricultural Workers' Diseases Diazinon 8.0916487989
MESH:D000419 Albuminuria Doxorubicin 4.2321441931
MESH:D000505 Alopecia Tretinoin 3.3615955085
MESH:D000544 Alzheimer Disease Folic Acid 2.9717116317
MESH:D000740 Anemia Fluorouracil 7.7515504547 17963324 16511603
MESH:D000740 Anemia Tetrachlorodibenzodioxin 7.7511748828
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.7619183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.1511256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.5415885639
MESH:D001169 Arthritis, Experimental Tretinoin 6.5416412693
MESH:D001172 Arthritis, Rheumatoid Methotrexate 4.5917286800
MESH:D001172 Arthritis, Rheumatoid Tretinoin 4.5916292516
MESH:D001249 Asthma Tretinoin 2.2416456186
MESH:D050197 Atherosclerosis Cadmium 3.4515687053
MESH:D001321 Autistic Disorder Folic Acid 2.8621388746
MESH:D001471 Barrett Esophagus Tretinoin 4.0916935849
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 19.6116206674
MESH:D001778 Blood Coagulation Disorders Clofibrate 19.6119483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 19.6112125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 19.6116197459 16206674
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.4615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.5615746008
MESH:D019046 Bone Marrow Neoplasms Cisplatin 10.9514601052
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 10.9514601052
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.0117868700
MESH:D001930 Brain Injuries Progesterone 3.9415665606 15845082 15380490
MESH:D001932 Brain Neoplasms Doxorubicin 3.5317150277
MESH:D001943 Breast Neoplasms marker/mechanism 18283316
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 10.6520146248 17474063
MESH:D001943 Breast Neoplasms bexarotene 10.6516344269 16818667
MESH:D001943 Breast Neoplasms Cisplatin 10.6519526202 18382427
MESH:D001943 Breast Neoplasms decitabine 10.6518320071 19208741
MESH:D001943 Breast Neoplasms Doxorubicin 10.6516935488 18695136 17426702 15939500 18382427 15692762 11325840 15993339 15567936 15634643 18234424 16322301 15668708 16595493 15994142 16826403 16115903 17983394 18628466 17369602 15136595 19526202 16264153 16096432
MESH:D001943 Breast Neoplasms Estradiol 10.6519861407 17289903 14630087 12948864 17018787 16675129 17261762 18497071
MESH:D001943 Breast Neoplasms Fluorouracil 10.6518608205 16557594 16595493 16110121 19217205 18357371 15136595
MESH:D001943 Breast Neoplasms Folic Acid 10.6516777985
MESH:D001943 Breast Neoplasms Methotrexate 10.6516978400
MESH:D001943 Breast Neoplasms Nickel 10.6515986119
MESH:D001943 Breast Neoplasms Progesterone 10.6515562024 17614352 16175315
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 10.6520435547
MESH:D001943 Breast Neoplasms Tretinoin 10.6516873071 16443354 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.2616813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.0311589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.1416111702
MESH:D002276 Carcinoid Tumor Doxorubicin 11.2516051944
MESH:D002276 Carcinoid Tumor Fluorouracil 11.2516051944
MESH:D002277 Carcinoma Fluorouracil 7.3417121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.3416835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.8316168501
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 13.1821507988 12619106 12907637
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 13.1811135700 14691202 15553829 16217749 15073043
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 13.1817982673
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 13.1817876044 18059187 16023760 16234567
MESH:D006528 Carcinoma, Hepatocellular Estradiol 13.1816924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 13.1817971768 16332177 16799960 17045692 18930000 17088986
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 13.181917145
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 5.4816247446
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 5.4812023789 16685392
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.5419014326
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 10.0316201981 1485588
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 10.0318695887
MESH:D002292 Carcinoma, Renal Cell Vinblastine 10.031485588
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.8412490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 16.7520419170
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 16.7518337622 17066447 6189445
MESH:D002294 Carcinoma, Squamous Cell decitabine 16.7519215824
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 16.756189445
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 16.7516757204 16280240 18986760 17066447
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 16.7516051514 16096774
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.1918850075 18670907 16120746
MESH:D009202 Cardiomyopathies Doxorubicin 3.3215476868 16269455 17308081 17351982 17329180 17131338 16242529 18627295 17007740 17519947 16952015 16364871 17974986 15505089 16612575 16109756 16651473 16731534 15792986 17382496 15811867 16455267 16278810 17924179 17928571
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.8316243910 17334414
MESH:D002318 Cardiovascular Diseases Folic Acid 7.0216755160
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 7.0216936243
MESH:D002386 Cataract Tretinoin 2.9017460283
MESH:D002471 Cell Transformation, Neoplastic Cadmium 14.2517332340
MESH:D002471 Cell Transformation, Neoplastic Clofibrate 14.251399818
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 14.2512371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 14.2518566989
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.2616129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.8916835633
MESH:D002779 Cholestasis Cyclosporine 6.9819486331
MESH:D002779 Cholestasis Ethinyl Estradiol 6.9816105132 17333356 17681005 11677210 17110522 15861022 16919318
MESH:D002822 Choriocarcinoma Tretinoin 4.8316461808
MESH:D002971 Cleft Lip Folic Acid 3.8121254359
MESH:D002972 Cleft Palate Folic Acid 9.0821254359 8946559
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 9.0812621046 16354765 15340226 8697196 15668235
MESH:D002972 Cleft Palate Tretinoin 9.089407595
MESH:D003092 Colitis Tretinoin 3.3917035595
MESH:D003110 Colonic Neoplasms decitabine 3.6517616700
MESH:D003110 Colonic Neoplasms Fluorouracil 3.6517725105 16510598 17172411 15001691 17016597 18772588 16340194 17018589 17169374 17287894
MESH:D015179 Colorectal Neoplasms arsenic trioxide 9.9520501625
MESH:D015179 Colorectal Neoplasms Cisplatin 9.9515273666
MESH:D015179 Colorectal Neoplasms decitabine 9.9518981723
MESH:D015179 Colorectal Neoplasms Doxorubicin 9.9518802399 18259882
MESH:D015179 Colorectal Neoplasms Fluorouracil 9.9517454858 14970324 16331619 17094418 18448328 15289873 16282729 17255274 20501625 18509181 18802399 17016601 15148649 18383874 17401013 18949393 17695437 17594712 16524972 18288408 16391804 16303861
MESH:D015179 Colorectal Neoplasms Folic Acid 9.9517245555 16985020 17087956 16963246 17116713
MESH:D015179 Colorectal Neoplasms Vinblastine 9.9518802399
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.7917141729 14669216
MESH:D023903 Coronary Restenosis arsenic trioxide 3.8812609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 5.1010525206
MESH:D019465 Craniofacial Abnormalities Methotrexate 5.109562676 12039119
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 5.1020055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 5.109142499 8800419 14991402 10589399 9664655 17551590 9125849 16925845 9211117 9224671
MESH:D003550 Cystic Fibrosis Methotrexate 3.9619747007
MESH:D007644 Darier Disease Fluorouracil 4.4716733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.8015213294
MESH:D017449 Dermatitis, Allergic Contact Nickel 3.6517244072 19470301 17100760
MESH:D003877 Dermatitis, Contact Nickel 4.342952479
MESH:D003882 Dermatomyositis Methotrexate 4.8120191521
MESH:D003924 Diabetes Mellitus, Type 2 Folic Acid 4.2816886840
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.2817107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.1419279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.1717187935
MESH:D056486 Drug-Induced Liver Injury Diquat 5.8418164269 18445702
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 5.8417416283
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 5.8420420201
MESH:D004362 Drug Toxicity Cisplatin 12.3912649298 12231392 19839026 15033597
MESH:D004362 Drug Toxicity Doxorubicin 12.3918602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 12.3911462148
MESH:D050171 Dyslipidemias Clofibrate 3.8316707586
MESH:D004417 Dyspnea Diazinon 4.4716487989
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.1011000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.8416714409 15322242 18230668
MESH:D004489 Edema, Cardiac Tretinoin 10.8418230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.0112538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 8.0117692515
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.7819294695
MESH:D016889 Endometrial Neoplasms Doxorubicin 16.0917359293
MESH:D016889 Endometrial Neoplasms Estradiol 16.0918566989 11473722 19148513
MESH:D016889 Endometrial Neoplasms Folic Acid 16.0917301261
MESH:D016889 Endometrial Neoplasms Tretinoin 16.0916569247
MESH:D004715 Endometriosis Mifepristone 13.7116134523
MESH:D004715 Endometriosis Progesterone 13.7116134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 13.7110568697 9294722
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.8318037988
MESH:D019446 Endotoxemia Lipopolysaccharides 4.0715328337 17637181 15821434
MESH:D004938 Esophageal Neoplasms arsenic trioxide 9.6712903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 9.6716530937
MESH:D004938 Esophageal Neoplasms Cisplatin 9.6717638652 15173087 16785472 15464296 16481741
MESH:D004938 Esophageal Neoplasms Fluorouracil 9.6717638652 15173087 16481741 16337965 16785472
MESH:D017889 Exfoliation Syndrome Folic Acid 5.1716504073
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.0411564622
MESH:D005124 Eye Abnormalities Tretinoin 8.0416938888 9664655
MESH:D005234 Fatty Liver arsenic trioxide 16.4115073043
MESH:D005234 Fatty Liver Clofibrate 16.4119224547
MESH:D005234 Fatty Liver Cyclosporine 16.4119224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 16.4115345470
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.1411858732
MESH:D005334 Fever Lipopolysaccharides 3.739205823 11852909
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 4.2619069698
MESH:D005355 Fibrosis Cyclosporine 12.8712168785 12639820
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 12.8720067830
MESH:D005355 Fibrosis Tretinoin 12.8717994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.9516904648
MESH:D005756 Gastritis Diquat 10.8715046732
MESH:D005756 Gastritis Folic Acid 10.8717171786
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.898708960
MESH:D005901 Glaucoma Folic Acid 4.7816504073
MESH:D005909 Glioblastoma Doxorubicin 6.5417150277
MESH:D005909 Glioblastoma Tretinoin 6.5417312396
MESH:D005910 Glioma Fluorouracil 2.7416145905
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.2610696789
MESH:D006086 Graft vs Host Disease Methotrexate 4.8316518429
MESH:D006258 Head and Neck Neoplasms Cisplatin 21.8715464296 15102660
MESH:D006258 Head and Neck Neoplasms decitabine 21.8719215824
MESH:D006258 Head and Neck Neoplasms Doxorubicin 21.8715692506
MESH:D006258 Head and Neck Neoplasms Fluorouracil 21.8715162350 15102660 18337622
MESH:D006258 Head and Neck Neoplasms Tretinoin 21.8716096774
MESH:D034381 Hearing Loss Cisplatin 4.0219898482
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.8316084493
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 4.1515464296
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 14.5720471113
MESH:D006330 Heart Defects, Congenital Folic Acid 14.5717286298 16524890
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 14.5711294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 14.579664655 14991402
MESH:D006331 Heart Diseases Doxorubicin 3.2616244372 12587719 16495754 17888722 18006777 16244371 14766674 16879835 17875725 16144979 16330681 18674790 16707910
MESH:D006333 Heart Failure Doxorubicin 3.1417481944
MESH:D006394 Hemangiosarcoma Doxorubicin 3.6115692506
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.0915720958
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 4.1016366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.0511000095
MESH:D006505 Hepatitis Diazinon 4.2716487989
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.5815340226 16120746 12621046
MESH:D006558 Herpes Genitalis Estradiol 4.7015709030
MESH:D015658 HIV Infections Nickel 3.6517263646
MESH:D006679 HIV Seropositivity Folic Acid 5.1717209195
MESH:D006689 Hodgkin Disease Cisplatin 10.8916170182 16200630
MESH:D006689 Hodgkin Disease Doxorubicin 10.8917606976 18501091 15147373
MESH:D006689 Hodgkin Disease Vinblastine 10.8918501091 18180244
MESH:D019584 Hot Flashes Estradiol 3.4217088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.7116959395 18606429 15340226 16354765 8697196
MESH:D006930 Hyperalgesia Tretinoin 2.9616870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.2516778211
MESH:D020138 Hyperhomocysteinemia Folic Acid 4.2216865747 16395265 16433478 16755160 16397167
MESH:D006973 Hypertension Cyclosporine 4.5210903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.5218670907 18850075
MESH:D007021 Hypospadias Ethinyl Estradiol 3.4916569931 16945680
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.0815869954
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.1612013081
MESH:D007248 Infertility, Male decitabine 14.3717581917
MESH:D007248 Infertility, Male Diazinon 14.3712948887 16466525
MESH:D007248 Infertility, Male Diquat 14.374850670
MESH:D007248 Infertility, Male Ethinyl Estradiol 14.3717937319
MESH:D007249 Inflammation Lipopolysaccharides 10.6117255318 12878042 17963957 17237260 9205823
MESH:D007249 Inflammation Nickel 10.6116166738
MESH:D007249 Inflammation Progesterone 10.6115869954
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 10.6112200463 12878042
MESH:D007333 Insulin Resistance Estradiol 2.7616627594 16393666
MESH:D007410 Intestinal Diseases Tretinoin 3.4517994277
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.3317255318
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 8.9716580747
MESH:D007569 Jaw Abnormalities Tretinoin 8.9715992940 17551590
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.1115604871
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.8115464296
MESH:D007674 Kidney Diseases Cadmium 17.0716226777 16322080 16962696
MESH:D007674 Kidney Diseases Cisplatin 17.0712649298 18289764 12231392 15190930 19839026
MESH:D007674 Kidney Diseases Cyclosporine 17.0718776723 10903974 8314463
MESH:D007674 Kidney Diseases Doxorubicin 17.0715369732 15699352 16775033
MESH:D007674 Kidney Diseases Estradiol 17.0715618244
MESH:D007676 Kidney Failure, Chronic Doxorubicin 9.1616707910
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 9.1616518626
MESH:D007680 Kidney Neoplasms Cyclosporine 10.8912371664
MESH:D007680 Kidney Neoplasms Estradiol 10.8915610895
MESH:D007680 Kidney Neoplasms Fluorouracil 10.8916985049
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 4.4611231351
MESH:D007805 Language Development Disorders Methotrexate 4.809562676
MESH:D007938 Leukemia arsenic trioxide 9.5415070760
MESH:D007938 Leukemia decitabine 9.5419235587 18980019
MESH:D007938 Leukemia Tretinoin 9.5417143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.8316085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.5117077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 10.6616972261
MESH:D007948 Leukemia, Monocytic, Acute U 0126 10.6616972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.1914633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 14.3219077051
MESH:D007951 Leukemia, Myeloid decitabine 14.3218454857 19117987 17236224
MESH:D007951 Leukemia, Myeloid Tretinoin 14.3216932348 16482212 19285840
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 5.7616467208 20471514 16968895 17050201 19850784
MESH:D015470 Leukemia, Myeloid, Acute decitabine 5.7618460780 18206229 19010910 19387464 17679729 18704418
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 5.7619850784 17596541 16294345
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.1318055864
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 6.9316823087 17869043 19075265 16966277 16112521 16330433 17107899 15622746 9834237 17649720 19035177 11161223 11468182 19225113 16331271 17217047 17712046 12679006 15748426 16891316 12712474 15213294 19642359 12018890 15336539
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 6.9319075265 17339181 12679006 17107899 17301526 17217047 19225113 16140955 16788101 19642359 17368321 19035177 16766008 9834237 16935935 16891316 15748426 17649720 17506722 17294898 19029980 16823087 16331271 17361223 17712046
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.0416882451
MESH:D007970 Leukopenia Lipopolysaccharides 4.3715821434
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.089224671
MESH:D008103 Liver Cirrhosis Methotrexate 3.5214986274
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 6.2616595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 6.2614659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 6.2612878042
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 6.2612878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 6.2616248980 18397230
MESH:D008107 Liver Diseases Chlorpyrifos 4.4815991261
MESH:D008107 Liver Diseases Folic Acid 4.4816877991
MESH:D008113 Liver Neoplasms Aflatoxin B1 16.3015890375 2125692 18177683 9163691
MESH:D008113 Liver Neoplasms arsenic trioxide 16.3014682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 16.3020195826 21137059
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 16.3019389873 21295105
MESH:D008113 Liver Neoplasms Fluorouracil 16.3017045692 18383874 16603448 15113037
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 16.3016984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 16.498603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 16.4920377131
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 16.4918164116
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 16.4916842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 16.4912151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.1115213294
MESH:D017563 Lung Diseases, Interstitial Methotrexate 4.6918516814
MESH:D055370 Lung Injury Lipopolysaccharides 3.6921114838
MESH:D008175 Lung Neoplasms Aflatoxin B1 12.2014755239
MESH:D008175 Lung Neoplasms arsenic trioxide 12.2019825857 11798837
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 12.2020464547 17053015 18569708 18520028 18816296 6695378 20869020 20064080 20135361
MESH:D008175 Lung Neoplasms bexarotene 12.2017849452
MESH:D008175 Lung Neoplasms Cisplatin 12.2011798837 17225452 6189445
MESH:D008175 Lung Neoplasms Doxorubicin 12.206189445 17418594
MESH:D008175 Lung Neoplasms Fluorouracil 12.2015246190
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 12.2011884234 19555203
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.4715086387
MESH:D008180 Lupus Erythematosus, Systemic Folic Acid 3.2417718048
MESH:D008223 Lymphoma decitabine 11.3619470736
MESH:D008223 Lymphoma Doxorubicin 11.3616098063
MESH:D008223 Lymphoma Methotrexate 11.3617352296
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.5317654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.2515621674
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 4.8311161223
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 12.6019196723 19196722 15591091
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 12.6015458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 12.6011807958 17203775 11408345 16891317
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 12.6017203775 11408345
MESH:D020149 Manganese Poisoning Estradiol 4.1519453300
MESH:D019767 Maxillofacial Abnormalities Folic Acid 5.3716832597
MESH:D008527 Medulloblastoma Tretinoin 2.6517453147
MESH:D008545 Melanoma Cisplatin 11.6812374674 16248763 12393984 15577323 18505091 16432458 18176117 17761969 11135225 18332650 16809738 12883367 17023156
MESH:D008545 Melanoma decitabine 11.6817785578 16505122
MESH:D008545 Melanoma Doxorubicin 11.6816827129
MESH:D008545 Melanoma Tretinoin 11.6816752155
MESH:D008545 Melanoma Vinblastine 11.6818176117 16248763 18332650 16432458 12374674 15577323 15577320 17761969 16809738 18505091
MESH:D008545 Melanoma Vitamin K 3 11.6819082730
MESH:D018328 Melanoma, Amelanotic Cisplatin 4.4515990972
MESH:D008591 Meningomyelocele Tretinoin 4.1116940565
MESH:D008654 Mesothelioma Cisplatin 6.0117638057
MESH:D008654 Mesothelioma Doxorubicin 6.0117638057
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.4616801185
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.2115792986
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 7.7116381670
MESH:D009062 Mouth Neoplasms Fluorouracil 7.7116757204 18986760
MESH:D052016 Mucositis Doxorubicin 11.4317415656
MESH:D052016 Mucositis Methotrexate 11.4317488658
MESH:D009101 Multiple Myeloma arsenic trioxide 6.6114977855 11468182 15949261 19549372 19417148
MESH:D009101 Multiple Myeloma decitabine 6.6118172295
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.3418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 11.2516105982 16882451
MESH:D009190 Myelodysplastic Syndromes decitabine 11.2519157545 16882708 19010910 18608210
MESH:D009190 Myelodysplastic Syndromes Tretinoin 11.2517596541
MESH:D009203 Myocardial Infarction Doxorubicin 2.8119429709 15857846
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.7612213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.0316810080
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.6516624393
MESH:D009362 Neoplasm Metastasis Doxorubicin 2.8218259882
MESH:D009369 Neoplasms Benzo(a)pyrene 13.9911141357
MESH:D009369 Neoplasms Cisplatin 13.9916773208
MESH:D009369 Neoplasms decitabine 13.9919116145 17925555 19470736
MESH:D009369 Neoplasms Fluorouracil 13.9918600527 18239605 16928823
MESH:D009369 Neoplasms Tretinoin 13.9916594593 16946489
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 4.4519196722
MESH:D009389 Neovascularization, Pathologic Estradiol 3.4117289903
MESH:D009395 Nephritis, Interstitial Cisplatin 4.1615464296
MESH:D009401 Nephrosis Doxorubicin 4.4516636307 16899518
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.1117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 8.3918481113 19348381
MESH:D009404 Nephrotic Syndrome Doxorubicin 8.3916889571 15640375
MESH:D009421 Nervous System Malformations Estradiol 14.5416427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 14.5414600291
MESH:D009421 Nervous System Malformations Tretinoin 14.549125849
MESH:D009436 Neural Tube Defects arsenic trioxide 11.0410525206
MESH:D009436 Neural Tube Defects Folic Acid 11.0417438019
MESH:D009436 Neural Tube Defects Tretinoin 11.049142499
MESH:D009447 Neuroblastoma Cisplatin 6.588761367
MESH:D009447 Neuroblastoma Doxorubicin 6.5815555623
MESH:D017599 Neuroectodermal Tumors Cisplatin 4.378761367
MESH:D020258 Neurotoxicity Syndromes Chlorpyrifos 7.5815081274
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 7.5816436463
MESH:D009503 Neutropenia Folic Acid 8.8216322990
MESH:D009503 Neutropenia Vinblastine 8.8217378895
MESH:D052556 Niemann-Pick Disease, Type C Clofibrate 4.629802331
MESH:D012516 Osteosarcoma Doxorubicin 3.8615930896
MESH:D010051 Ovarian Neoplasms arsenic trioxide 25.2419769630 12452020 16624393
MESH:D010051 Ovarian Neoplasms Cisplatin 25.2417225452 15464296 19769630 6897625
MESH:D010051 Ovarian Neoplasms decitabine 25.2419259094 19331143
MESH:D010051 Ovarian Neoplasms Estradiol 25.2419401270
MESH:D010051 Ovarian Neoplasms Mifepristone 25.2416525653
MESH:D010051 Ovarian Neoplasms Progesterone 25.2416525653 17393432
MESH:D010051 Ovarian Neoplasms Tretinoin 25.2416936753
MESH:D010051 Ovarian Neoplasms U 0126 25.2416211241
MESH:D010146 Pain Tretinoin 2.6516870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 15.0215580305
MESH:D010190 Pancreatic Neoplasms Cisplatin 15.0219003803
MESH:D010190 Pancreatic Neoplasms decitabine 15.0219294695
MESH:D010190 Pancreatic Neoplasms Fluorouracil 15.0215113037 16929163 19003803 16500647
MESH:D010190 Pancreatic Neoplasms Tretinoin 15.0215976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.3911578682
MESH:D010212 Papilloma Hydrogen Peroxide 3.7712065085
MESH:D010235 Paraganglioma arsenic trioxide 3.8619927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.9212520081
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 4.0015464296
MESH:D016491 Peripheral Vascular Diseases Cadmium 5.0615687053
MESH:D003557 Phyllodes Tumor Doxorubicin 4.8317983394
MESH:D010997 Pleural Neoplasms Cisplatin 12.8317638057
MESH:D010997 Pleural Neoplasms Doxorubicin 12.8317638057
MESH:D011014 Pneumonia Lipopolysaccharides 4.2312224865 11605937
MESH:D011041 Poisoning Diazinon 4.0617603234
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.2518163543
MESH:D011230 Precancerous Conditions Cyclosporine 2.9512371664
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 2.8711222880 11896295 11399792 11118676
MESH:D055728 Primary Myelofibrosis decitabine 4.4117616702
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.5920887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 1.8819131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 1.8817292933
MESH:D011471 Prostatic Neoplasms Cadmium 1.8817075824
MESH:D011471 Prostatic Neoplasms Doxorubicin 1.8816868541 16729912 16888761 18437689 15749863 15897917
MESH:D011471 Prostatic Neoplasms Estradiol 1.8816740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 1.8818626508 19082440
MESH:D011507 Proteinuria Tretinoin 3.3116636307
MESH:D011537 Pruritus Ethinyl Estradiol 2.9916919318 15861022
MESH:D011565 Psoriasis Cyclosporine 5.5116882103
MESH:D011565 Psoriasis Methotrexate 5.5117410198
MESH:D011625 Pterygium Tretinoin 4.4716723453
MESH:D012004 Rectal Neoplasms Fluorouracil 3.7418286688 16160472 18722050 15538739
MESH:D051437 Renal Insufficiency Cisplatin 21.8415464296
MESH:D051437 Renal Insufficiency Doxorubicin 21.8417922066
MESH:D051437 Renal Insufficiency Folic Acid 21.8415728788
MESH:D051437 Renal Insufficiency Methotrexate 21.8417352296
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.5210835634
MESH:D012135 Respiratory Sounds Chlorpyrifos 4.3216611668 17119214 11874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.5318990726
MESH:D012140 Respiratory Tract Diseases Chlorpyrifos 4.5616611668 17119214
MESH:D012208 Rhabdomyosarcoma decitabine 9.9519155313
MESH:D012208 Rhabdomyosarcoma Tretinoin 9.9516283617 16116481
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.7418045962
MESH:D012509 Sarcoma Doxorubicin 3.7117203757 15675481 15625365 17710206 16767912 18313854
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 15.4916646077
MESH:D012512 Sarcoma, Ewing's Cisplatin 15.4914601052
MESH:D012512 Sarcoma, Ewing's Doxorubicin 15.4916326096 14601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.4617846226
MESH:D012559 Schizophrenia Folic Acid 2.8516641680
MESH:D012729 Sex Chromosome Aberrations Chlorpyrifos 5.766418539
MESH:D012871 Skin Diseases Folic Acid 3.1618709164
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 20.4410029692 19755658
MESH:D012878 Skin Neoplasms Doxorubicin 20.4415692506
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 20.4412065085
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 20.448532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 20.4416192470
MESH:D012878 Skin Neoplasms Tretinoin 20.4416467112
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 5.0115464296
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.2517203757 16767912 15625365
MESH:D013088 Spermatocele Ethinyl Estradiol 3.6116709447
MESH:D013118 Spinal Cord Diseases Folic Acid 5.1716361298
MESH:D013119 Spinal Cord Injuries Progesterone 3.9515862959 16503802
MESH:D013274 Stomach Neoplasms arsenic trioxide 9.8217007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 9.8220155912 2093021
MESH:D013274 Stomach Neoplasms Cisplatin 9.8218396642 17522103 15958060
MESH:D013274 Stomach Neoplasms decitabine 9.8219037991
MESH:D013274 Stomach Neoplasms Fluorouracil 9.8218396642 17498489 16424979 18567086 19015929 16951190 15786421 17522103 17172411 19084572
MESH:D013274 Stomach Neoplasms Folic Acid 9.8217171786
MESH:D013274 Stomach Neoplasms Tretinoin 9.8217261132
MESH:D020521 Stroke Folic Acid 4.0716517955
MESH:D013576 Syndactyly Methotrexate 4.729562676
MESH:D013736 Testicular Neoplasms Cisplatin 4.3317225452 15464296
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.8815821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.3211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.8815669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.5712697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 15.1219014326
MESH:D013964 Thyroid Neoplasms decitabine 15.1217967635
MESH:D013964 Thyroid Neoplasms Doxorubicin 15.1216010429 17909728
MESH:D013964 Thyroid Neoplasms Tretinoin 15.1217045167 16026305
MESH:D013978 Tibial Fractures Estradiol 4.3519048282
MESH:D014062 Tongue Neoplasms Fluorouracil 8.8916280240
MESH:D014062 Tongue Neoplasms Tretinoin 8.8916051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.6415213294
MESH:D014376 Tuberculosis Tretinoin 3.0316040207
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 14.4020435036 12973940 12845720 11780464
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 14.4017053015
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 14.4017225452 12973940 15464296
MESH:D001749 Urinary Bladder Neoplasms decitabine 14.4017616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 14.4017653716
MESH:D014570 Urologic Diseases Diazinon 4.9516487989
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 14.2916803524
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 14.2916803524
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 14.2916129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 2.9914692618
MESH:D014604 Uveal Neoplasms decitabine 11.7217785578
MESH:D014604 Uveal Neoplasms Tretinoin 11.7216752155
MESH:D014605 Uveitis Cyclosporine 3.651336536
MESH:D014625 Vaginal Neoplasms Cisplatin 10.2515577323
MESH:D014625 Vaginal Neoplasms Vinblastine 10.2515577323
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.2612125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.2514671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 3.9017678736 17638931 17334414 16364871
MESH:D014820 Vitiligo Tretinoin 3.7516761959
MESH:D014839 Vomiting Cisplatin 4.3911897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.9215886252
MESH:D009396 Wilms Tumor Tretinoin 3.6916287080
MESH:D014985 Xerophthalmia Cyclosporine 4.1117120751
Pathway ID Pathway Name
KEGG:04310 Wnt signaling pathway
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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