AutismKB 2.0

Annotation Detail for FOXD4


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Basic Information Top
Gene Symbol:FOXD4 ( FKHL9,FOXD4A,FREAC5,MGC105106 )
Gene Full Name: forkhead box D4
Band: 9p24.3
Quick LinksEntrez ID:2298; OMIM: 601092; Uniprot ID:FOXD4_HUMAN; ENSEMBL ID: ENSG00000170122; HGNC ID: 3805
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of FOXD4 mRNAaffects expression 16483693
D009151 Mustard Gas Mustard Gas results in increased expression of FOXD4 mRNAincreases expression 15674843
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.4418287403
MESH:D001249 Asthma Mustard Gas 2.8210378619
MESH:D001768 Blister Mustard Gas 6.0519167455
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 6.0515286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 6.0510378619 17687719
MESH:D004487 Edema Mustard Gas 3.8511402378 9260866 11428631 11428647
MESH:D004890 Erythema Mustard Gas 6.059357497
MESH:D007249 Inflammation Mustard Gas 2.999260866 11402378 17524151 9357497 8975870 16001271 11428620 11428647 11428631
MESH:D008171 Lung Diseases Mustard Gas 3.7618161513 18702808
MESH:D008175 Lung Neoplasms Mustard Gas 2.188781369 3148597
MESH:D009503 Neutropenia Mustard Gas 4.587688884 16761898
MESH:D011041 Poisoning Mustard Gas 4.4015727166
MESH:D011537 Pruritus Mustard Gas 4.9818058305
MESH:D011658 Pulmonary Fibrosis Mustard Gas 3.0717620002 17894541 17720292 17266442 10334151
MESH:D012871 Skin Diseases Mustard Gas 2.8015451306 12880345 16961503
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018