AutismKB 2.0

Annotation Detail for DIP2C


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Basic Information Top
Gene Symbol:DIP2C ( FLJ34444,FLJ44075,KIAA0934 )
Gene Full Name: DIP2 disco-interacting protein 2 homolog C (Drosophila)
Band: 10p15.3
Quick LinksEntrez ID:22982; OMIM: 611380; Uniprot ID:DIP2C_HUMAN; ENSEMBL ID: ENSG00000151240; HGNC ID: 29150
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of DIP2C mRNAaffects expression 17562736
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of DIP2C proteinaffects expression 20106945
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of DIP2C mRNAdecreases expression 20064835
20106945
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of DIP2C mRNAdecreases expression 15336504
C014347 decitabine decitabine results in increased expression of DIP2C mRNAincreases expression 19194470
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of DIP2C mRNAaffects binding|decreases expression|increases activity 19710929
C006253 pirinixic acid pirinixic acid results in increased expression of DIP2C mRNAincreases expression 18301758
D012643 Selenium Selenium results in decreased expression of DIP2C mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055371 Acute Lung Injury pirinixic acid 3.4218653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0420127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 2.806695378
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.8816434500
MESH:D000799 Angioedema Acetaminophen 4.2910982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.4319183758
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.4319483382
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.1920146248 17474063
MESH:D001943 Breast Neoplasms decitabine 2.1919208741 18320071
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 3.003084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 3.0021507988 12619106 12907637
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.9020419170
MESH:D002294 Carcinoma, Squamous Cell decitabine 4.9019215824
MESH:D002386 Cataract Acetaminophen 2.7310977129
MESH:D002779 Cholestasis pirinixic acid 3.0319176532
MESH:D003092 Colitis Selenium 4.1417936198
MESH:D003110 Colonic Neoplasms decitabine 2.3717616700
MESH:D015179 Colorectal Neoplasms decitabine 2.1018981723
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5318249437
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.0110915739 18713872 14986274 10663392 15968718 2444490 11461765 19164858 18071297 19420014 19416960 19923254 19739265 17906064 11287661 12153990 17522070 10774834 11421492 12594235 11834606 11743745 16227642 12540782 14725611 14550746 16781746 15619225 12705907 11739529 17562736 11529661 12958197 12392966 16393943 16177239 19370779 19085960 16485898 16109766 16081117
MESH:D056486 Drug-Induced Liver Injury Selenium 4.0115131321
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.5419426721
MESH:D004487 Edema pirinixic acid 2.7612083418
MESH:D004701 Endocrine Gland Neoplasms decitabine 5.5619294695
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0616530937
MESH:D005234 Fatty Liver pirinixic acid 3.0419236843 20131406
MESH:D005756 Gastritis Acetaminophen 4.1216983495
MESH:D006258 Head and Neck Neoplasms decitabine 3.6619215824
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.7820471113
MESH:D006333 Heart Failure pirinixic acid 7.4820558911
MESH:D006333 Heart Failure Selenium 7.4817162251
MESH:D006529 Hepatomegaly pirinixic acid 3.3519772884 18467677 16221962 19176532
MESH:D006930 Hyperalgesia Acetaminophen 2.9216870215
MESH:D006943 Hyperglycemia pirinixic acid 3.4520558911
MESH:D007248 Infertility, Male decitabine 3.3817581917
MESH:D007251 Influenza, Human Selenium 4.6416624496
MESH:D007333 Insulin Resistance pirinixic acid 2.8016306350
MESH:D007674 Kidney Diseases Acetaminophen 2.3415629191 12587719
MESH:D007676 Kidney Failure, Chronic Selenium 4.1716518626
MESH:D007938 Leukemia decitabine 3.1919235587 18980019
MESH:D007951 Leukemia, Myeloid decitabine 4.2819117987 18454857 17236224
MESH:D015470 Leukemia, Myeloid, Acute decitabine 2.4118460780 18206229 19010910 19387464 17679729 18704418
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.9118055864
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008107 Liver Diseases Acetaminophen 1.6816611625 19014921 11587558 19460945 19784758 12969438 12587719 16610002
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5016871587 17185352
MESH:D008113 Liver Neoplasms Aflatoxin B1 7.9215890375 9163691 18177683 2125692
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 7.9221137059 20195826
MESH:D008113 Liver Neoplasms pirinixic acid 7.9215890375 20007298 16377806
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 2.908603461
MESH:D008175 Lung Neoplasms Aflatoxin B1 2.4814755239
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 2.4818569708 6695378 18816296 18520028 20464547 20064080 20135361 17053015 20869020
MESH:D008223 Lymphoma decitabine 3.6119470736
MESH:D008325 Mammary Neoplasms, Experimental Selenium 2.9215318939
MESH:D008545 Melanoma decitabine 2.2717785578 16505122
MESH:D008546 Melanoma, Experimental Acetaminophen 3.9319513568
MESH:D008654 Mesothelioma Selenium 2.8815107826
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.4016381670
MESH:D009101 Multiple Myeloma decitabine 3.5418172295
MESH:D009135 Muscular Diseases pirinixic acid 3.8616239165
MESH:D009190 Myelodysplastic Syndromes decitabine 3.5219157545 16882708 19010910 18608210
MESH:D009203 Myocardial Infarction pirinixic acid 2.2419151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.1616411023
MESH:D009369 Neoplasms Benzo(a)pyrene 8.9511141357
MESH:D009369 Neoplasms decitabine 8.9519470736 19116145 17925555
MESH:D009369 Neoplasms pirinixic acid 8.9517405874
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1018514411
MESH:D009765 Obesity pirinixic acid 1.8620558911
MESH:D010051 Ovarian Neoplasms decitabine 2.7219259094 19331143
MESH:D010146 Pain Acetaminophen 2.6216870215
MESH:D010190 Pancreatic Neoplasms decitabine 2.8419294695
MESH:D010954 Plasmacytoma Selenium 5.3315087411
MESH:D055728 Primary Myelofibrosis decitabine 5.0917616702
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9317292933
MESH:D015427 Reperfusion Injury pirinixic acid 2.5019058328
MESH:D012208 Rhabdomyosarcoma decitabine 4.7119155313
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 6.0910029692 19755658
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 6.098532709
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.512093021 20155912
MESH:D013274 Stomach Neoplasms decitabine 2.5119037991
MESH:D013964 Thyroid Neoplasms decitabine 3.5417967635
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 5.4417053015
MESH:D001749 Urinary Bladder Neoplasms decitabine 5.4419087683 17616700
MESH:D014581 Urticaria Acetaminophen 3.2810982225
MESH:D014604 Uveal Neoplasms decitabine 5.3617785578
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA134961070
    • No data
    Releated disease ID Related disease Name
    PA443560Breast Neoplasms
    No data
    Drug Bank Top

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    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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