Annotation Detail for HMGXB3
Basic Information
Top
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D001194 |
Asbestos |
Asbestos affects the expression of HMGXB3 mRNA | affects expression | 17297452
|
| C006253 |
pirinixic acid |
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of HMGXB3 mRNA | affects binding|increases activity|increases expression | 19710929
|
| D012643 |
Selenium |
Selenium results in increased expression of HMGXB3 mRNA | increases expression | 19244175
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.64 | 18653653 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
4.22 | 16434500 |
| MESH:D050197 |
Atherosclerosis |
|
Asbestos |
4.45 | 18795166 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.63 | 19483382 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
3.15 | 19176532 |
| MESH:D003092 |
Colitis |
|
Selenium |
4.43 | 17936198 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.59 | 18249437 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Selenium |
2.26 | 15131321 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
2.96 | 12083418 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
3.25 | 19236843 20131406 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
7.78 | 20558911 |
| MESH:D006333 |
Heart Failure |
|
Selenium |
7.78 | 17162251 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.64 | 16221962 18467677 19176532 19772884 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.63 | 20558911 |
| MESH:D007251 |
Influenza, Human |
|
Selenium |
5.06 | 16624496 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.90 | 16306350 |
| MESH:D007676 |
Kidney Failure, Chronic |
|
Selenium |
4.37 | 16518626 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
1.94 | 15890375 16377806 20007298 |
| MESH:D008175 |
Lung Neoplasms |
|
Asbestos |
3.18 | 12111688 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Selenium |
3.02 | 15318939 |
| MESH:D008654 |
Mesothelioma |
|
Asbestos |
7.13 | 18709470 16564556 18310086 16319530 16919927 |
| MESH:D008654 |
Mesothelioma |
|
Selenium |
7.13 | 15107826 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
4.16 | 16239165 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.29 | 19151258 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.29 | 16411023 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.12 | 17405874 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
1.89 | 20558911 |
| MESH:D010954 |
Plasmacytoma |
|
Selenium |
5.76 | 15087411 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.56 | 19058328 |
Related Pathway Information