Annotation Detail for CEP152
Basic Information Top
| Gene Symbol: | CEP152 ( FLJ21594,KIAA0912 ) |
|---|---|
| Gene Full Name: | centrosomal protein 152kDa |
| Band: | 15q21.1 |
| Quick Links | Entrez ID:22995; OMIM: 613529; Uniprot ID:CE152_HUMAN; ENSEMBL ID: ENSG00000103995; HGNC ID: 29298 |
| Relate to Another Database: | SFARIGene; denovo-db |
| No data |
| No data |
| Pathway ID | Pathway Name |
|---|---|
| Cell Cycle, Mitotic |
| No data |
| No data |
| Pathway ID | Pathway Name |
|---|---|
| 500383 | Loss of proteins required for interphase microtubule organization from the centrosome |
| 500384 | Loss of Nlp from mitotic centrosomes |
Related Diseases/Disorders| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| C006253 | pirinixic acid | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of CEP152 mRNA | affects binding|decreases expression|increases activity | 19710929 |
| D012402 | Rotenone | Rotenone results in increased expression of CEP152 mRNA | increases expression | 19013527 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D055371 | Acute Lung Injury | pirinixic acid | 3.72 | 18653653 | |
| MESH:D018248 | Adenoma, Liver Cell | pirinixic acid | 4.37 | 16434500 | |
| MESH:D001778 | Blood Coagulation Disorders | pirinixic acid | 3.70 | 19483382 | |
| MESH:D002779 | Cholestasis | pirinixic acid | 3.19 | 19176532 | |
| MESH:D003876 | Dermatitis, Atopic | pirinixic acid | 2.61 | 18249437 | |
| MESH:D004487 | Edema | pirinixic acid | 3.02 | 12083418 | |
| MESH:D005234 | Fatty Liver | pirinixic acid | 3.31 | 19236843 20131406 | |
| MESH:D006333 | Heart Failure | pirinixic acid | 2.81 | 20558911 | |
| MESH:D006529 | Hepatomegaly | pirinixic acid | 3.76 | 16221962 19176532 19772884 18467677 | |
| MESH:D006943 | Hyperglycemia | pirinixic acid | 3.69 | 20558911 | |
| MESH:D007333 | Insulin Resistance | pirinixic acid | 2.93 | 16306350 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | pirinixic acid | 1.35 | 15474484 | |
| MESH:D008113 | Liver Neoplasms | pirinixic acid | 1.95 | 20007298 16377806 15890375 | |
| OMIM:604321 | MICROCEPHALY, PRIMARY AUTOSOMAL RECESSIVE, 4 | marker/mechanism | |||
| MESH:D009135 | Muscular Diseases | pirinixic acid | 4.27 | 16239165 | |
| MESH:D009203 | Myocardial Infarction | pirinixic acid | 2.30 | 19151258 | |
| MESH:D015428 | Myocardial Reperfusion Injury | pirinixic acid | 3.33 | 16411023 | |
| MESH:D009369 | Neoplasms | pirinixic acid | 2.14 | 17405874 | |
| MESH:D009410 | Nerve Degeneration | Rotenone | 4.26 | 17356569 18619942 15790535 | |
| MESH:D009765 | Obesity | pirinixic acid | 1.90 | 20558911 | |
| MESH:D010300 | Parkinson Disease | Rotenone | 3.11 | 11535288 19232380 15451049 16412576 18619942 16140633 11445065 19114014 18191903 | |
| MESH:D020734 | Parkinsonian Disorders | Rotenone | 4.58 | 15927086 15795934 15574749 18197244 | |
| MESH:D015427 | Reperfusion Injury | pirinixic acid | 2.58 | 19058328 | |
| MESH:C537533 | Seckel syndrome 1 | marker/mechanism | 21131973 |
| Pathway ID | Pathway Name |
|---|---|
| REACT:152 | Cell Cycle, Mitotic |