AutismKB 2.0

Annotation Detail for FAIM2


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Basic Information Top
Gene Symbol:FAIM2 ( KIAA0950,LFG,LFG2,NGP35,NMP35,TMBIM2 )
Gene Full Name: Fas apoptotic inhibitory molecule 2
Band: 12q13.12
Quick LinksEntrez ID:23017; OMIM: 604306; Uniprot ID:FAIM2_HUMAN; ENSEMBL ID: ENSG00000135472; HGNC ID: 17067
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
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Pathway IDPathway Name
200067FAS (CD95) signaling pathway
No data
No data
Related Diseases/Disorders Top
No data
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Desease Name
Body mass index
weight
METABOLIC
waist circumference
Desease Name
Waist circumference
Body mass index
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene results in decreased expression of FAIM2 mRNAdecreases expression 20406850
D000643 Ammonium Chloride Ammonium Chloride affects the expression of FAIM2 mRNAaffects expression 16483693
D019207 beta Carotene beta Carotene results in increased expression of FAIM2 mRNAincreases expression 17034753
D008770 Methylnitrosourea Methylnitrosourea results in increased expression of FAIM2 mRNAincreases expression 17412507
C116926 rofecoxib rofecoxib results in decreased expression of FAIM2 mRNAdecreases expression 17070997
C025643 vinclozolin vinclozolin affects the expression of FAIM2 mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.0218287403
MESH:D000230 Adenocarcinoma Methylnitrosourea 3.1815113128 15688392
MESH:D001008 Anxiety Disorders vinclozolin 3.8919015723
MESH:D001169 Arthritis, Experimental rofecoxib 4.5216690336
MESH:D002545 Brain Ischemia beta Carotene 5.5516157235
MESH:D001943 Breast Neoplasms Methylnitrosourea 3.1311306469 16253758 14633655
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 1.7816705839
MESH:D002386 Cataract Methylnitrosourea 4.1512484553
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 7.746135515
MESH:D002471 Cell Transformation, Neoplastic Methylnitrosourea 7.747505956 2727394
MESH:D003110 Colonic Neoplasms rofecoxib 3.3412902858
MESH:D003456 Cryptorchidism vinclozolin 4.7214966744
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.4418551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 2.0421346803 18551238
MESH:D004715 Endometriosis rofecoxib 5.1615652904
MESH:D005354 Fibrosarcoma Methylnitrosourea 5.6911555667
MESH:D030342 Genetic Diseases, Inborn vinclozolin 5.4016973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.8216417039
MESH:D005910 Glioma Methylnitrosourea 3.669825942
MESH:D015658 HIV Infections beta Carotene 4.1916960176
MESH:D007248 Infertility, Male Methylnitrosourea 7.817193160
MESH:D007248 Infertility, Male vinclozolin 7.8116467254
MESH:D007410 Intestinal Diseases rofecoxib 5.4515831440
MESH:D007417 Intestinal Polyps rofecoxib 5.7211245490
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 3.2416705839
MESH:D007984 Leydig Cell Tumor vinclozolin 5.1916417039
MESH:D017880 Limb Deformities, Congenital Methylnitrosourea 4.4215526292
MESH:D008106 Liver Cirrhosis, Experimental rofecoxib 3.0817565644
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 2.247678174
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 7.012876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental beta Carotene 7.0117113696
MESH:D038061 Lower Extremity Deformities, Congenital Methylnitrosourea 5.8816080182
MESH:D008175 Lung Neoplasms beta Carotene 3.3316401635
MESH:D008175 Lung Neoplasms Methylnitrosourea 3.3318062963
MESH:D008223 Lymphoma Methylnitrosourea 4.2311418001 16257854
MESH:D016393 Lymphoma, B-Cell Methylnitrosourea 5.1214633661
MESH:D008325 Mammary Neoplasms, Experimental Methylnitrosourea 3.7719196723 16619500 17020996 10767621 10838139 15313902 16944150 11751437 16051031 15688392 14633655 15113128 12931682 17131329 16827153 14999141 11807958
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.327678174 18551238
MESH:D009369 Neoplasms beta Carotene 6.3217051425
MESH:D009369 Neoplasms Methylnitrosourea 6.3215533788
MESH:D009374 Neoplasms, Experimental Methylnitrosourea 4.8912696579
MESH:D009442 Neurilemmoma Methylnitrosourea 5.9511555667
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.7416049721
MESH:D010003 Osteoarthritis rofecoxib 4.5516690336
MESH:D010149 Pain, Postoperative rofecoxib 5.9116678543 18165598
MESH:D010190 Pancreatic Neoplasms Methylnitrosourea 3.4516965848
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 4.3618042343 18220299 19015723
MESH:D011469 Prostatic Diseases vinclozolin 5.4018220299
MESH:D011471 Prostatic Neoplasms Methylnitrosourea 4.0615682402 12376480
MESH:D011472 Prostatitis vinclozolin 5.4018629315
MESH:D012162 Retinal Degeneration Methylnitrosourea 4.6418155124 18172121
MESH:D012175 Retinoblastoma Methylnitrosourea 5.9511555667
MESH:D012640 Seizures 2,6-dinitrotoluene 2.7418551238
MESH:D013272 Stomach Diseases beta Carotene 5.5517638125
MESH:D013274 Stomach Neoplasms Methylnitrosourea 2.7015930296 16257854 18593901
MESH:D013276 Stomach Ulcer beta Carotene 4.5812500499
MESH:D013953 Thymus Neoplasms Methylnitrosourea 5.6911418001
MESH:D013964 Thyroid Neoplasms Methylnitrosourea 4.167505956 3078959
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 2.3916049721
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.7810091137
No data
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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