Annotation Detail for UNC13A
Basic Information Top
| Gene Symbol: | UNC13A ( KIAA1032,Munc13-1 ) |
|---|---|
| Gene Full Name: | unc-13 homolog A (C. elegans) |
| Band: | 19p13.11 |
| Quick Links | Entrez ID:23025; OMIM: 609894; Uniprot ID:UN13A_HUMAN; ENSEMBL ID: ENSG00000130477; HGNC ID: 23150 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| No data |
| No data |
| Desease Name |
|---|
| Amyotrophic Lateral Sclerosis |
| NEUROLOGICAL |
| Desease Name |
|---|
| Amyotrophic lateral sclerosis |
| No data |
| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D003024 | Clozapine | Clozapine results in decreased expression of UNC13A mRNA | decreases expression | 15860345 |
| D006220 | Haloperidol | Haloperidol results in decreased expression of UNC13A mRNA | decreases expression | 15860345 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000380 | Agranulocytosis | Clozapine | 5.82 | 14617031 16160616 12649775 | |
| MESH:D000690 | Amyotrophic Lateral Sclerosis | marker/mechanism | 19734901 | ||
| MESH:D001321 | Autistic Disorder | Haloperidol | 2.71 | 18080171 19368416 | |
| MESH:D002375 | Catalepsy | Haloperidol | 5.80 | 1977408 15215559 | |
| MESH:D003072 | Cognition Disorders | Clozapine | 5.73 | 17123785 | |
| MESH:D016757 | Death, Sudden, Cardiac | Haloperidol | 5.45 | 20210726 | |
| MESH:D003704 | Dementia | Haloperidol | 5.13 | 11575062 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Clozapine | 3.06 | 16402076 | |
| MESH:D006970 | Disorders of Excessive Somnolence | Clozapine | 6.62 | 15331141 | |
| MESH:D050171 | Dyslipidemias | Clozapine | 4.53 | 16402076 | |
| MESH:D006948 | Hyperkinesis | Clozapine | 5.79 | 16046005 | |
| MESH:D008064 | Lipidoses | Clozapine | 4.30 | 17567588 | |
| MESH:D001523 | Mental Disorders | Clozapine | 11.53 | 16856516 | |
| MESH:D001523 | Mental Disorders | Haloperidol | 11.53 | 16856516 | |
| MESH:D024821 | Metabolic Syndrome X | Clozapine | 4.85 | 19142101 | |
| MESH:D009765 | Obesity | Clozapine | 3.10 | 18515891 19142110 | |
| MESH:D011595 | Psychomotor Agitation | Haloperidol | 5.72 | 11575062 | |
| MESH:D011618 | Psychotic Disorders | Clozapine | 10.32 | 15331141 | |
| MESH:D011618 | Psychotic Disorders | Haloperidol | 10.32 | 11575062 | |
| MESH:D012559 | Schizophrenia | Clozapine | 4.27 | 20107430 20521320 18855531 17667964 20580759 19369910 17726453 20521326 11151749 20168265 18806925 11763009 17123785 20452607 16141801 | |
| MESH:D012559 | Schizophrenia | Haloperidol | 4.27 | 1830565 20107430 18513383 19369910 | |
| MESH:D017180 | Tachycardia, Ventricular | Haloperidol | 5.38 | 20210726 | |
| MESH:D015430 | Weight Gain | Clozapine | 4.94 | 16141801 20521320 20107430 20564506 17502770 16402076 | |
| MESH:D015431 | Weight Loss | Clozapine | 5.96 | 17933447 |
| No data |