AutismKB 2.0

Annotation Detail for XPO7


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:XPO7 ( EXP7,KIAA0745,RANBP16 )
Gene Full Name: exportin 7
Band: 8p21.3
Quick LinksEntrez ID:23039; OMIM: 606140; Uniprot ID:XPO7_HUMAN; ENSEMBL ID: ENSG00000130227; HGNC ID: 14108
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000638 Amiodarone Amiodarone results in decreased expression of XPO7 mRNAdecreases expression 17991464
D002117 Calcitriol Calcitriol results in decreased expression of XPO7 mRNAdecreases expression 18614847
16847355
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of XPO7 mRNAincreases expression 17942748
C051890 irinotecan irinotecan analog results in decreased expression of XPO7 mRNAdecreases expression 18927307
D014212 Tretinoin Tretinoin results in decreased expression of XPO7 mRNAdecreases expression 18614847
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.5517505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8814692618
MESH:D000505 Alopecia Tretinoin 3.9015955085
MESH:D001145 Arrhythmias, Cardiac Amiodarone 4.1518218290 20041841 18057881
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.9511256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.8815885639
MESH:D001169 Arthritis, Experimental Tretinoin 7.8816412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.3316292516
MESH:D001249 Asthma Tretinoin 2.4316456186
MESH:D001281 Atrial Fibrillation Amiodarone 4.1618651412 19698954
MESH:D001471 Barrett Esophagus Tretinoin 4.8416935849
MESH:D001778 Blood Coagulation Disorders Amiodarone 10.5219483382
MESH:D001778 Blood Coagulation Disorders Tretinoin 10.5216197459 16206674
MESH:D001943 Breast Neoplasms Calcitriol 2.2811237771
MESH:D001943 Breast Neoplasms Tretinoin 2.2816166294 16443354 16873071
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 5.1316813970
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.7716168501
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 1.911917145
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 5.0511237771
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 5.0516096774 16051514
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.9919225199 15710769
MESH:D002341 Carotid Artery Thrombosis Amiodarone 5.6218974383
MESH:D002386 Cataract Tretinoin 3.2817460283
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 5.1316129372
MESH:D002779 Cholestasis Ethinyl Estradiol 3.1317110522 16919318 15861022 17333356 16105132 17681005 11677210
MESH:D002822 Choriocarcinoma Tretinoin 5.7716461808
MESH:D002972 Cleft Palate Tretinoin 2.799407595
MESH:D003092 Colitis Tretinoin 4.1917035595
MESH:D003110 Colonic Neoplasms irinotecan 2.6417725105 17287894
MESH:D015179 Colorectal Neoplasms irinotecan 2.3617159606 16391804 18259882 15273666 17454858 16303861 18509181
MESH:D019465 Craniofacial Abnormalities Tretinoin 1.839142499 9125849 16925845 9664655 14991402 8800419 10589399 17551590 9211117 9224671
MESH:D056486 Drug-Induced Liver Injury Amiodarone 2.4615265979 18218290
MESH:D004489 Edema, Cardiac Tretinoin 5.0818230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 10.6015138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 10.6012538720
MESH:D016889 Endometrial Neoplasms Tretinoin 3.3216569247
MESH:D005124 Eye Abnormalities Tretinoin 3.8416938888 9664655
MESH:D005234 Fatty Liver Amiodarone 9.0914986274
MESH:D005234 Fatty Liver Ethinyl Estradiol 9.0915345470
MESH:D005355 Fibrosis Tretinoin 3.9917994277
MESH:D005909 Glioblastoma Tretinoin 3.2217312396
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.4116096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.7716084493
MESH:D006330 Heart Defects, Congenital Tretinoin 3.0514991402 9664655
MESH:D006529 Hepatomegaly Amiodarone 4.2315265979
MESH:D006930 Hyperalgesia Tretinoin 3.5016870215
MESH:D006937 Hypercholesterolemia Amiodarone 4.259751232 8137927
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 5.0516778211
MESH:D007021 Hypospadias Ethinyl Estradiol 4.2916569931 16945680
MESH:D007037 Hypothyroidism Amiodarone 5.0018020914 17991464
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.8712013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.7117937319
MESH:D007410 Intestinal Diseases Tretinoin 4.2517994277
MESH:D007569 Jaw Abnormalities Tretinoin 4.2715992940 17551590
MESH:D007938 Leukemia Tretinoin 2.9217143497
MESH:D007951 Leukemia, Myeloid Tretinoin 4.0716932348 19285840 16482212
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.1219850784 17596541 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.3719035177 19075265 16140955 16891316 16766008 16823087 17368321 17361223 16331271 17712046 17217047 17649720 15748426 17107899 9834237 19225113 12679006 19029980 16788101 19642359 17294898 17506722 16935935 17301526 17339181
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.559224671
MESH:D008064 Lipidoses Amiodarone 3.7615342952 17567588
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 1.8116248980 18397230
MESH:D008133 Long QT Syndrome Amiodarone 3.8517391786 11989578 15350150
MESH:D008171 Lung Diseases Amiodarone 3.6012587719
MESH:D017563 Lung Diseases, Interstitial Amiodarone 5.0918516814
MESH:D008527 Medulloblastoma Tretinoin 2.9017453147
MESH:D008545 Melanoma Tretinoin 1.9816752155
MESH:D008591 Meningomyelocele Tretinoin 4.9116940565
MESH:D052016 Mucositis irinotecan 5.5517159606
MESH:D009181 Mycoses Amiodarone 5.5117974566 12754197
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.2617596541
MESH:D009362 Neoplasm Metastasis irinotecan 3.2818259882
MESH:D009369 Neoplasms Tretinoin 2.5516946489 16594593
MESH:D009421 Nervous System Malformations Tretinoin 4.229125849
MESH:D009436 Neural Tube Defects Tretinoin 3.279142499
MESH:D009447 Neuroblastoma irinotecan 3.648761367
MESH:D017599 Neuroectodermal Tumors irinotecan 5.278761367
MESH:D010051 Ovarian Neoplasms Tretinoin 2.4316936753
MESH:D010146 Pain Tretinoin 3.2016870215
MESH:D010190 Pancreatic Neoplasms Tretinoin 2.5615976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.0911578682
MESH:D011470 Prostatic Hyperplasia Calcitriol 5.3215572423
MESH:D011471 Prostatic Neoplasms Calcitriol 3.4916289102 16644109 18247401 15754350 12479363
MESH:D011507 Proteinuria Tretinoin 4.0116636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.8516919318 15861022
MESH:D011625 Pterygium Tretinoin 5.3316723453
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.9612490602 11597910 12832656
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.5016283617 16116481
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 5.6218724381
MESH:D012878 Skin Neoplasms Tretinoin 2.7516467112
MESH:D013088 Spermatocele Ethinyl Estradiol 4.5516709447
MESH:D013274 Stomach Neoplasms irinotecan 2.7115723263
MESH:D013274 Stomach Neoplasms Tretinoin 2.7117261132
MESH:D013276 Stomach Ulcer Amiodarone 3.6818087811
MESH:D013610 Tachycardia Amiodarone 4.7311238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.6319225199
MESH:D019851 Thrombophilia Ethinyl Estradiol 4.0211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.4815669648
MESH:D013959 Thyroid Diseases Amiodarone 5.3719731979
MESH:D013964 Thyroid Neoplasms Tretinoin 3.2917045167 16026305
MESH:D013971 Thyrotoxicosis Amiodarone 5.3418020914 19584973
MESH:D014062 Tongue Neoplasms Tretinoin 4.1416051514
MESH:D016171 Torsades de Pointes Amiodarone 4.7311989578 17467628
MESH:D014376 Tuberculosis Tretinoin 3.4316040207
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 4.0216129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.7414692618
MESH:D014604 Uveal Neoplasms Tretinoin 5.2216752155
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.9114671159 15869587
MESH:D014820 Vitiligo Tretinoin 4.5016761959
MESH:D009396 Wilms Tumor Tretinoin 4.2916287080
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved