AutismKB 2.0

Annotation Detail for MON2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MON2 ( KIAA1040,MGC35493 )
Gene Full Name: MON2 homolog (S. cerevisiae)
Band: 12q14.1
Quick LinksEntrez ID:23041; OMIM: NA; Uniprot ID:MON2_HUMAN; ENSEMBL ID: ENSG00000061987; HGNC ID: 29177
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of MON2 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of MON2 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of MON2 mRNAaffects expression 17562736
D003010 Clorgyline Clorgyline results in increased expression of MON2 mRNAincreases expression 19691856
D011374 Progesterone Progesterone results in increased expression of MON2 mRNAincreases expression 18070364
D012643 Selenium Selenium results in decreased expression of MON2 mRNAdecreases expression 19244175
D014810 Vitamin E Vitamin E results in decreased expression of MON2 mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.2910982225
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.7817868700
MESH:D001930 Brain Injuries Progesterone 4.6215665606 15380490 15845082
MESH:D001943 Breast Neoplasms Progesterone 2.4215562024 16175315 17614352
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.2916050911
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 4.7116705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 4.7116705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.713084413
MESH:D002386 Cataract Acetaminophen 2.7310977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 2.956135515
MESH:D003092 Colitis Selenium 4.1417936198
MESH:D019465 Craniofacial Abnormalities Vitamin E 1.9219769572
MESH:D003490 Cyanosis 2,4-dinitrotoluene 12.1218551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 12.1218551238
MESH:D003929 Diabetic Neuropathies Progesterone 4.8517187935
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 9.5521346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 9.5521346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 9.5519164858 17906064 10663392 16177239 19923254 16781746 10774834 11739529 15619225 14725611 12153990 16109766 18713872 19416960 19370779 11834606 16485898 11743745 11529661 16227642 2444490 12705907 12594235 16081117 14550746 18071297 11421492 10915739 17522070 12958197 17562736 11461765 19420014 15968718 16393943 19739265 12540782 19085960 12392966 11287661 14986274
MESH:D056486 Drug-Induced Liver Injury Selenium 9.5515131321
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.5419426721
MESH:C538011 Eales disease Vitamin E 5.159068938
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 4.1117692515
MESH:D004715 Endometriosis Progesterone 4.0316134523
MESH:D005756 Gastritis Acetaminophen 4.1216983495
MESH:D006330 Heart Defects, Congenital Vitamin E 3.1216080930
MESH:D006333 Heart Failure Selenium 3.2317162251
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.7816490937 16863852
MESH:D019584 Hot Flashes Vitamin E 4.4114716179
MESH:D006930 Hyperalgesia Acetaminophen 2.9216870215
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.7615869954
MESH:D007249 Inflammation Progesterone 2.7215869954
MESH:D007251 Influenza, Human Selenium 12.4816624496
MESH:D007251 Influenza, Human Vitamin E 12.4816624496
MESH:D007674 Kidney Diseases Acetaminophen 6.4515629191 12587719
MESH:D007674 Kidney Diseases Vitamin E 6.4512488133
MESH:D007676 Kidney Failure, Chronic Selenium 4.1716518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 8.1516705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 8.1516705839
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 1.9016169303
MESH:D008107 Liver Diseases Acetaminophen 1.6812969438 16611625 19784758 12587719 19460945 16610002 19014921 11587558
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5017185352 16871587
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 2.237678174
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.702876784 6135515 2876786
MESH:D008171 Lung Diseases Vitamin E 3.3516863852
MESH:D008175 Lung Neoplasms Vitamin E 1.9011062179
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 6.6911408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Selenium 6.6915318939
MESH:D008546 Melanoma, Experimental Acetaminophen 3.9319513568
MESH:D008654 Mesothelioma Selenium 2.8815107826
MESH:D009336 Necrosis 2,4-dinitrotoluene 11.7018551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 11.707678174 18551238
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1018514411
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 9.7816049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 9.7816049721
MESH:D010051 Ovarian Neoplasms Progesterone 2.5917393432 16525653
MESH:D010146 Pain Acetaminophen 2.6216870215
MESH:D010954 Plasmacytoma Selenium 5.3315087411
MESH:D011471 Prostatic Neoplasms Clorgyline 3.6119691856
MESH:D011471 Prostatic Neoplasms Vitamin E 3.6115084515
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.9318045962
MESH:D012640 Seizures 2,4-dinitrotoluene 6.4718551238
MESH:D012640 Seizures 2,6-dinitrotoluene 6.4718551238
MESH:D012871 Skin Diseases Vitamin E 2.5018709164
MESH:D013119 Spinal Cord Injuries Progesterone 4.6815862959 16503802
MESH:D020521 Stroke Vitamin E 3.7416517955
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 5.3216049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 5.3216049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 13.3510091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 13.3510091137
MESH:D014581 Urticaria Acetaminophen 3.2810982225
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved