Annotation Detail for PDXDC1
Basic Information
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| Gene Symbol: | PDXDC1 ( KIAA0251,LP8165 ) |
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| Gene Full Name: | pyridoxal-dependent decarboxylase domain containing 1 |
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| Band: | 16p13.11 |
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| Quick Links | Entrez ID:23042; OMIM: NA; Uniprot ID:PDXD1_HUMAN; ENSEMBL ID: ENSG00000179889; HGNC ID: 28995 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Desease Name |
|---|
| height |
| DEVELOPMENTAL |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D004040 |
Dietary Carbohydrates |
Dietary Carbohydrates results in decreased expression of PDXDC1 mRNA | decreases expression | 17490981
|
| D004997 |
Ethinyl Estradiol |
Ethinyl Estradiol affects the expression of PDXDC1 mRNA | affects expression | 17555576
|
| D015741 |
Metribolone |
Metribolone results in increased expression of PDXDC1 protein | increases expression | 17152098
|
| D013629 |
Tamoxifen |
Tamoxifen affects the expression of PDXDC1 mRNA | affects expression | 17555576
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000008 |
Abdominal Neoplasms |
|
Tamoxifen |
5.27 | 14745880 |
| MESH:D000152 |
Acne Vulgaris |
|
Ethinyl Estradiol |
4.66 | 17505938 |
| MESH:D000230 |
Adenocarcinoma |
|
Ethinyl Estradiol |
1.88 | 14692618 |
| MESH:D001161 |
Arteriosclerosis |
|
Ethinyl Estradiol |
4.02 | 11256880 |
| MESH:D001169 |
Arthritis, Experimental |
|
Ethinyl Estradiol |
2.89 | 15885639 |
| MESH:D001943 |
Breast Neoplasms |
|
Tamoxifen |
2.17 | 20544844 19189210 20859285 19155303 19410462 18351453 20065188 19142967 16818667 18815881 17242785 18855134 18984771 11161223 19066611 19189212 20005174 19059307 20390343 16202921 19487384 20135344 19103187 19011961 19115204 19221464 21152245 15565566 19200415 19244106 17049068 18629630 19288272 19084267 18997820 15668708 18821012 16273361 17440819 17893378 21138602 17261762 18425577 16873071 19289846 |
| MESH:D018270 |
Carcinoma, Ductal, Breast |
|
Tamoxifen |
5.07 | 19066611 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Tamoxifen |
1.86 | 16924424 |
| MESH:D002295 |
Carcinoma, Transitional Cell |
|
Tamoxifen |
4.01 | 17572228 |
| MESH:D002779 |
Cholestasis |
|
Ethinyl Estradiol |
3.17 | 17681005 17110522 16919318 15861022 16105132 11677210 17333356 |
| MESH:D003711 |
Demyelinating Diseases |
|
Tamoxifen |
4.92 | 19031437 |
| MESH:D003928 |
Diabetic Nephropathies |
|
Tamoxifen |
3.84 | 19279558 |
| MESH:D004681 |
Encephalomyelitis, Autoimmune, Experimental |
|
Ethinyl Estradiol |
10.68 | 12538720 |
| MESH:D004681 |
Encephalomyelitis, Autoimmune, Experimental |
|
Tamoxifen |
10.68 | 19031437 |
| MESH:D016889 |
Endometrial Neoplasms |
|
Tamoxifen |
3.29 | 17893378 20544844 16202921 19155303 |
| MESH:D005234 |
Fatty Liver |
|
Ethinyl Estradiol |
9.14 | 15345470 |
| MESH:D005234 |
Fatty Liver |
|
Tamoxifen |
9.14 | 14986274 19224547 |
| MESH:D052776 |
Female Urogenital Diseases |
|
Tamoxifen |
3.45 | 16709447 |
| MESH:D018221 |
Fibromatosis, Abdominal |
|
Tamoxifen |
5.16 | 14745880 |
| MESH:D018222 |
Fibromatosis, Aggressive |
|
Tamoxifen |
4.81 | 19069698 |
| MESH:D007021 |
Hypospadias |
|
Ethinyl Estradiol |
4.37 | 16569931 16945680 |
| MESH:D007247 |
Infertility, Female |
|
Ethinyl Estradiol |
3.92 | 12013081 |
| MESH:D007248 |
Infertility, Male |
|
Ethinyl Estradiol |
2.73 | 17937319 |
| MESH:D007249 |
Inflammation |
|
Tamoxifen |
2.53 | 19457130 |
| MESH:D007680 |
Kidney Neoplasms |
|
Tamoxifen |
3.38 | 18625569 |
| MESH:D008064 |
Lipidoses |
|
Tamoxifen |
3.43 | 15342952 17567588 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Tamoxifen |
1.75 | 18564211 |
| MESH:D008113 |
Liver Neoplasms |
|
Tamoxifen |
2.33 | 16684651 |
| MESH:D008175 |
Lung Neoplasms |
|
Tamoxifen |
1.74 | 18625569 |
| MESH:D015674 |
Mammary Neoplasms, Animal |
|
Tamoxifen |
4.39 | 19428831 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Tamoxifen |
2.86 | 14580682 16827153 11731420 19196722 19196723 |
| MESH:D020149 |
Manganese Poisoning |
|
Tamoxifen |
5.27 | 19453300 |
| MESH:D008545 |
Melanoma |
|
Tamoxifen |
1.92 | 19393235 12393984 |
| MESH:D018328 |
Melanoma, Amelanotic |
|
Tamoxifen |
4.81 | 15990972 |
| MESH:D009362 |
Neoplasm Metastasis |
|
Tamoxifen |
2.67 | 19393235 |
| MESH:D009364 |
Neoplasm Recurrence, Local |
|
Tamoxifen |
2.61 | 19410462 |
| MESH:D009376 |
Neoplasms, Hormone-Dependent |
|
Tamoxifen |
4.72 | 19189210 19200415 19196722 |
| MESH:D016584 |
Panic Disorder |
|
Ethinyl Estradiol |
4.15 | 11578682 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Tamoxifen |
3.09 | 15067354 |
| MESH:D011537 |
Pruritus |
|
Ethinyl Estradiol |
3.94 | 16919318 15861022 |
| MESH:D013088 |
Spermatocele |
|
Ethinyl Estradiol |
14.11 | 16709447 |
| MESH:D013088 |
Spermatocele |
|
Tamoxifen |
14.11 | 16709447 |
| MESH:D013119 |
Spinal Cord Injuries |
|
Tamoxifen |
4.67 | 19457130 |
| MESH:D019851 |
Thrombophilia |
|
Ethinyl Estradiol |
4.08 | 11994571 |
| MESH:D013927 |
Thrombosis |
|
Ethinyl Estradiol |
3.52 | 15669648 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
Tamoxifen |
2.48 | 17572228 8653321 16712894 |
| MESH:D014594 |
Uterine Neoplasms |
|
Ethinyl Estradiol |
3.80 | 14692618 |
| MESH:D020246 |
Venous Thrombosis |
|
Ethinyl Estradiol |
3.97 | 14671159 15869587 |
| Drugbank ID |
Action |
Drug Name |
Description |
|---|
| DB00114 |
- |
Pyridoxal Phosphate |
Dietary supplement;Micronutrient;Vitamin B Complex |
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