Annotation Detail for GGA2
Basic Information Top
| Gene Symbol: | GGA2 ( FLJ20966,KIAA1080,VEAR ) |
|---|---|
| Gene Full Name: | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| Band: | 16p12.2 |
| Quick Links | Entrez ID:23062; OMIM: 606005; Uniprot ID:GGA2_HUMAN; ENSEMBL ID: ENSG00000103365; HGNC ID: 16064 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Diseases/Disorders| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of GGA2 mRNA | affects expression | 17562736 |
| D004041 | Dietary Fats | Dietary Fats results in decreased expression of GGA2 mRNA | decreases expression | 18042831 |
| C475919 | hydroxytamoxifen | hydroxytamoxifen results in increased expression of GGA2 mRNA | increases expression | 16849584 |
| C041786 | palm oil | palm oil results in decreased expression of GGA2 mRNA | decreases expression | 18042831 |
| D014415 | Tunicamycin | Tunicamycin results in decreased expression of GGA2 mRNA | decreases expression | 17127020 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000799 | Angioedema | Acetaminophen | 4.45 | 10982225 | |
| MESH:D001161 | Arteriosclerosis | Dietary Fats | 4.37 | 15238619 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.40 | 18445737 | |
| MESH:D001943 | Breast Neoplasms | Dietary Fats | 2.25 | 20435547 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.40 | 3084413 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.77 | 10977129 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.66 | 19164858 11287661 10663392 12705907 16393943 18071297 12392966 10915739 16485898 16781746 15619225 14986274 10774834 12958197 19370779 17906064 11529661 11461765 11739529 19416960 16227642 16177239 11743745 19085960 14550746 15968718 12540782 14725611 2444490 19739265 18713872 16081117 17562736 11421492 11834606 17522070 12594235 16109766 19923254 19420014 12153990 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 4.71 | 19426721 | |
| MESH:D050171 | Dyslipidemias | Dietary Fats | 3.70 | 18367378 | |
| MESH:D005234 | Fatty Liver | Dietary Fats | 3.61 | 17967931 19551842 19004024 18296743 | |
| MESH:D005355 | Fibrosis | Dietary Fats | 4.01 | 18296743 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.29 | 16983495 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 2.99 | 16870215 | |
| MESH:D006937 | Hypercholesterolemia | Dietary Fats | 3.97 | 21332399 | |
| MESH:D006949 | Hyperlipidemias | Dietary Fats | 4.02 | 21332399 | |
| MESH:D007249 | Inflammation | Dietary Fats | 2.59 | 20412841 | |
| MESH:D007333 | Insulin Resistance | Dietary Fats | 3.32 | 11836018 18457598 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.38 | 15629191 12587719 | |
| MESH:D008103 | Liver Cirrhosis | Dietary Fats | 3.05 | 18296743 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.69 | 19784758 16610002 12969438 16611625 19460945 11587558 19014921 12587719 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.58 | 17185352 16871587 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.05 | 19513568 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.18 | 18514411 | |
| MESH:D009765 | Obesity | Dietary Fats | 2.35 | 18674790 21332399 19632207 17217161 16723640 11836018 18457598 20518802 20132043 | |
| MESH:D010146 | Pain | Acetaminophen | 2.69 | 16870215 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.38 | 10982225 | |
| MESH:D015430 | Weight Gain | Dietary Fats | 4.06 | 16723640 |
| Pathway ID | Pathway Name |
|---|---|
| KEGG:04142 | Lysosome |