AutismKB 2.0

Annotation Detail for TBC1D2B


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TBC1D2B ( FLJ20166,KIAA1055 )
Gene Full Name: TBC1 domain family, member 2B
Band: 15q24.3-q25.1
Quick LinksEntrez ID:23102; OMIM: NA; Uniprot ID:TBD2B_HUMAN; ENSEMBL ID: ENSG00000167202; HGNC ID: 29183
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of TBC1D2B mRNAaffects expression 17484886
D016572 Cyclosporine Cyclosporine results in decreased expression of TBC1D2B mRNAdecreases expression 20106945
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of TBC1D2B mRNAdecreases expression 15576828
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.8117505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8914692618
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 4.1211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.9115885639
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 4.4315673190 16097048 16050911 18705752 16011737 15700767 15721981 16124888 16192424 16227642 10355542 3786805
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 1.8618788625
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.8212371664
MESH:D002779 Cholestasis Cyclosporine 8.8819486331
MESH:D002779 Cholestasis Ethinyl Estradiol 8.8817333356 16105132 17110522 15861022 17681005 16919318 11677210
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 2.136884620 19085960 9327722 7120509 2869522 16177239 7179309 4309450 21278145 7440962 10915739 6623471 17522070 11566570 3786805 15027814 19336974 16227642 10092053 15998439 15968718 3732212
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.7712538720
MESH:D005234 Fatty Liver Carbon Tetrachloride 16.0312795759 19224547 12631006 15959796 16045604 17595544 61145 16239168
MESH:D005234 Fatty Liver Cyclosporine 16.0319224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 16.0315345470
MESH:D005355 Fibrosis Carbon Tetrachloride 10.9318705752
MESH:D005355 Fibrosis Cyclosporine 10.9312168785 12639820
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.968708960
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 5.1615720958
MESH:D006505 Hepatitis Carbon Tetrachloride 4.1819110552 19900420
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 5.2716899240
MESH:D006973 Hypertension Cyclosporine 2.2310903974
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.7415338365
MESH:D007021 Hypospadias Ethinyl Estradiol 4.4616569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.9912013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.7617937319
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.3115604871
MESH:D007674 Kidney Diseases Cyclosporine 2.568314463 10903974 18776723
MESH:D007680 Kidney Neoplasms Cyclosporine 3.1212371664
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 3.0217157831 16943688 11408273 11903743 17334410 16221502 21278145 16239168 17174718
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 1.7517944888 17805973 14716833 17714472 17565644 17761835 14724832 15673190 15650968 16136751 18481824 18429990 18705752 15730626 15893842 17869086 17766677 17631135 15057751 12898905 17823541 17922224 17900296 17721639 18187930 15876570 17976157 17481882 12666154 12667390 15959796 16027843 15362042 12741479 15123356 14512876 18263696 17640975 16033810 18210741 16097048 16638106 18472332 12445418 16116963 18418968 12609069 10355542 18277467 12649538 18166357 16015684 18420326 15996030 16011737 17708605 18395095 18205269 11481614 15370692 20821823 12546737 18317297 12445421 15052691 14620537 14716496 18395914 14748882 18006644 18339082 15925388 18251166 12632514 18279442 16248980 17698563 18472094 15338365 12389079 13678700 18054572 18412020 18156304 17525996 15931870 12958196 12632512 16192424 17557913 15818738 12586293 18376398
MESH:D008107 Liver Diseases Carbon Tetrachloride 2.1617285989 16964402 15830285 15720792 16246199
MESH:D017093 Liver Failure Carbon Tetrachloride 4.8215123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 4.1416899240 14706259
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 2.3519294768
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 2.8612014681 15583823
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.6516801185
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.3117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.7019348381 18481113
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.2211578682
MESH:D011230 Precancerous Conditions Cyclosporine 3.6412371664
MESH:D011537 Pruritus Ethinyl Estradiol 4.0515861022 16919318
MESH:D011565 Psoriasis Cyclosporine 2.3416882103
MESH:D013088 Spermatocele Ethinyl Estradiol 4.8116709447
MESH:D019851 Thrombophilia Ethinyl Estradiol 4.1511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.5715669648
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.8814692618
MESH:D014605 Uveitis Cyclosporine 4.851336536
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 4.0215869587 14671159
MESH:D014985 Xerophthalmia Cyclosporine 5.3117120751
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved