AutismKB 2.0

Annotation Detail for TNRC6B


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Basic Information Top
Gene Symbol:TNRC6B ( KIAA1093 )
Gene Full Name: trinucleotide repeat containing 6B
Band: 22q13.1
Quick LinksEntrez ID:23112; OMIM: 610740; Uniprot ID:TNR6B_HUMAN; ENSEMBL ID: ENSG00000100354; HGNC ID: 29190
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
No data
Desease Name
height
prostate cancer
CANCER
DEVELOPMENTAL
Desease Name
Height
Prostate cancer
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of TNRC6B mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of TNRC6B mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of TNRC6B mRNAaffects expression 16483693
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of TNRC6B mRNAdecreases expression 20064835
D005419 Flavonoids Flavonoids results in decreased expression of TNRC6B mRNAdecreases expression 18035473
C025643 vinclozolin vinclozolin affects the expression of TNRC6B mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.0218287403
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0420127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 2.826695378
MESH:D000799 Angioedema Acetaminophen 4.3610982225
MESH:D001008 Anxiety Disorders vinclozolin 3.8919015723
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.4919183758
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.0020146248 17474063
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 2.9416705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 2.943084413
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1220419170
MESH:D002386 Cataract Acetaminophen 2.7510977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 2.986135515
MESH:D003456 Cryptorchidism vinclozolin 4.7214966744
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.4418551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 3.9721346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 3.9717522070 19420014 15619225 19739265 11421492 14725611 12392966 18713872 16109766 12705907 12958197 18071297 16227642 11529661 11834606 19416960 16177239 17562736 19085960 11739529 15968718 17906064 10774834 14550746 14986274 11743745 16081117 10663392 19370779 11461765 12540782 10915739 11287661 19164858 12594235 16781746 16393943 16485898 19923254 2444490 12153990
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.6219426721
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0716530937
MESH:D005756 Gastritis Acetaminophen 4.1916983495
MESH:D030342 Genetic Diseases, Inborn vinclozolin 5.4016973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.8216417039
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8020471113
MESH:D006930 Hyperalgesia Acetaminophen 2.9516870215
MESH:D007248 Infertility, Male vinclozolin 3.2416467254
MESH:D007249 Inflammation Flavonoids 2.7917296493
MESH:D007674 Kidney Diseases Acetaminophen 2.3612587719 15629191
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 3.2416705839
MESH:D007984 Leydig Cell Tumor vinclozolin 5.1916417039
MESH:D008107 Liver Diseases Acetaminophen 1.6912969438 16610002 19014921 16611625 19784758 11587558 19460945 12587719
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5417185352 16871587
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 4.827678174
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 4.8221137059 20195826
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.722876784 6135515 2876786
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 1.5720464547 20064080 18569708 18816296 6695378 20135361 17053015 18520028 20869020
MESH:D008546 Melanoma, Experimental Acetaminophen 3.9819513568
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.4316381670
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.327678174 18551238
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3011141357
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1418514411
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.7416049721
MESH:D010146 Pain Acetaminophen 2.6516870215
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 4.3618042343 18220299 19015723
MESH:D011469 Prostatic Diseases vinclozolin 5.4018220299
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9217292933
MESH:D011472 Prostatitis vinclozolin 5.4018629315
MESH:D012640 Seizures 2,6-dinitrotoluene 2.7418551238
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.4919755658 10029692
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.562093021 20155912
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 5.3216049721
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 5.3217053015
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.7810091137
MESH:D014581 Urticaria Acetaminophen 3.3310982225
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA134992981
    • No data
    Releated disease ID Related disease Name
    PA445425Prostatic Neoplasms
    No data
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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