Annotation Detail for NFASC
Basic Information
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| Pathway ID | Pathway Name |
|---|
| hsa04514 | Cell adhesion molecules (CAMs) |
| Pathway ID | Pathway Name |
|---|
| Axon guidance |
| Pathway ID | Pathway Name |
|---|
| 500102 | Neurofascin interactions |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C023514 |
2,6-dinitrotoluene |
2,6-dinitrotoluene results in decreased expression of NFASC mRNA | decreases expression | 20406850
|
| D000643 |
Ammonium Chloride |
Ammonium Chloride affects the expression of NFASC mRNA | affects expression | 16483693
|
| D001564 |
Benzo(a)pyrene |
Benzo(a)pyrene results in decreased expression of NFASC mRNA | decreases expression | 20127859
|
| C116926 |
rofecoxib |
rofecoxib results in decreased expression of NFASC mRNA | decreases expression | 17070997
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000138 |
Acidosis |
|
Ammonium Chloride |
4.19 | 18287403 |
| MESH:D000230 |
Adenocarcinoma |
|
Benzo(a)pyrene |
2.06 | 20464547 20127859 |
| MESH:D000236 |
Adenoma |
|
Benzo(a)pyrene |
2.86 | 6695378 |
| MESH:D017544 |
Aortic Aneurysm, Abdominal |
|
Benzo(a)pyrene |
4.64 | 19183758 |
| MESH:D001169 |
Arthritis, Experimental |
|
rofecoxib |
4.57 | 16690336 |
| MESH:D001943 |
Breast Neoplasms |
|
Benzo(a)pyrene |
1.99 | 17474063 20146248 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,6-dinitrotoluene |
1.79 | 16705839 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Benzo(a)pyrene |
2.13 | 20419170 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
2,6-dinitrotoluene |
3.03 | 6135515 |
| MESH:D003110 |
Colonic Neoplasms |
|
rofecoxib |
3.35 | 12902858 |
| MESH:D003490 |
Cyanosis |
|
2,6-dinitrotoluene |
4.58 | 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,6-dinitrotoluene |
2.05 | 18551238 21346803 |
| MESH:D004715 |
Endometriosis |
|
rofecoxib |
5.25 | 15652904 |
| MESH:D004938 |
Esophageal Neoplasms |
|
Benzo(a)pyrene |
2.08 | 16530937 |
| MESH:D006330 |
Heart Defects, Congenital |
|
Benzo(a)pyrene |
2.83 | 20471113 |
| MESH:D007410 |
Intestinal Diseases |
|
rofecoxib |
5.59 | 15831440 |
| MESH:D007417 |
Intestinal Polyps |
|
rofecoxib |
5.83 | 11245490 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,6-dinitrotoluene |
3.32 | 16705839 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
rofecoxib |
3.08 | 17565644 |
| MESH:D008113 |
Liver Neoplasms |
|
2,6-dinitrotoluene |
4.89 | 7678174 |
| MESH:D008113 |
Liver Neoplasms |
|
Benzo(a)pyrene |
4.89 | 21137059 20195826 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
2,6-dinitrotoluene |
2.77 | 2876784 2876786 6135515 |
| MESH:D008175 |
Lung Neoplasms |
|
Benzo(a)pyrene |
1.57 | 17053015 6695378 18816296 20869020 18569708 20135361 20464547 20064080 18520028 |
| MESH:D009062 |
Mouth Neoplasms |
|
Benzo(a)pyrene |
3.50 | 16381670 |
| MESH:D009336 |
Necrosis |
|
2,6-dinitrotoluene |
4.49 | 7678174 18551238 |
| MESH:D009369 |
Neoplasms |
|
Benzo(a)pyrene |
2.33 | 11141357 |
| MESH:D009784 |
Occupational Diseases |
|
2,6-dinitrotoluene |
3.83 | 16049721 |
| MESH:D010003 |
Osteoarthritis |
|
rofecoxib |
4.59 | 16690336 |
| MESH:D010149 |
Pain, Postoperative |
|
rofecoxib |
6.11 | 18165598 16678543 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Benzo(a)pyrene |
2.91 | 17292933 |
| MESH:D012640 |
Seizures |
|
2,6-dinitrotoluene |
2.79 | 18551238 |
| MESH:D012878 |
Skin Neoplasms |
|
Benzo(a)pyrene |
2.52 | 10029692 19755658 |
| MESH:D013274 |
Stomach Neoplasms |
|
Benzo(a)pyrene |
1.56 | 2093021 20155912 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,6-dinitrotoluene |
5.39 | 16049721 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
Benzo(a)pyrene |
5.39 | 17053015 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,6-dinitrotoluene |
4.95 | 10091137 |
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