AutismKB 2.0

Annotation Detail for POGZ


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Basic Information Top
Gene Symbol:POGZ ( KIAA0461,MGC71543,SUHW5,ZNF280E,ZNF635,ZNF635m )
Gene Full Name: pogo transposable element with ZNF domain
Band: 1q21.3
Quick LinksEntrez ID:23126; OMIM: NA; Uniprot ID:POGZ_HUMAN; ENSEMBL ID: ENSG00000143442; HGNC ID: 18801
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of POGZ mRNAaffects expression 21346803
C051890 irinotecan irinotecan analog results in decreased expression of POGZ mRNAdecreases expression 18927307
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 1.7916705839
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 3.096135515
MESH:D003110 Colonic Neoplasms irinotecan 2.6517725105 17287894
MESH:D015179 Colorectal Neoplasms irinotecan 2.3716391804 15273666 18259882 17454858 16303861 18509181 17159606
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.7818551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 2.0721346803 18551238
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 3.4116705839
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 2.297678174
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.822876784 2876786 6135515
MESH:D052016 Mucositis irinotecan 5.8917159606
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.7518551238 7678174
MESH:D009362 Neoplasm Metastasis irinotecan 3.3218259882
MESH:D009447 Neuroblastoma irinotecan 3.698761367
MESH:D017599 Neuroectodermal Tumors irinotecan 5.628761367
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.9416049721
MESH:D012640 Seizures 2,6-dinitrotoluene 2.8518551238
MESH:D013274 Stomach Neoplasms irinotecan 2.3615723263
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 2.4316049721
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 5.2010091137
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018