AutismKB 2.0

Annotation Detail for MAST2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MAST2 ( FLJ39200,KIAA0807,MAST205,MTSSK,RP4-533D7.1 )
Gene Full Name: microtubule associated serine/threonine kinase 2
Band: 1p34.1
Quick LinksEntrez ID:23139; OMIM: 612257; Uniprot ID:MAST2_HUMAN; ENSEMBL ID: ENSG00000086015; HGNC ID: 19035
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of MAST2 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of MAST2 mRNAaffects expression 17562736
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.9110982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 2.9916705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 2.993084413
MESH:D002386 Cataract Acetaminophen 2.8310977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 3.096135515
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.7818551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 4.0821346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.0816485898 10915739 2444490 11739529 14550746 19085960 10774834 15968718 12594235 16781746 11834606 19416960 12540782 18071297 15619225 17906064 19420014 11743745 12392966 16081117 10663392 16227642 19923254 19739265 18713872 17522070 16393943 12705907 12153990 12958197 17562736 16109766 19370779 16177239 19164858 11461765 14986274 11287661 11529661 11421492 14725611
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.1719426721
MESH:D005756 Gastritis Acetaminophen 4.7416983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1116870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4412587719 15629191
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 3.4116705839
MESH:D008107 Liver Diseases Acetaminophen 1.7119014921 11587558 19460945 16611625 19784758 12969438 12587719 16610002
MESH:D017114 Liver Failure, Acute Acetaminophen 3.7417185352 16871587
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 2.297678174
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.822876784 2876786 6135515
MESH:D008546 Melanoma, Experimental Acetaminophen 4.3319513568
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.7518551238 7678174
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3118514411
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.9416049721
MESH:D010146 Pain Acetaminophen 2.8216870215
MESH:D012640 Seizures 2,6-dinitrotoluene 2.8518551238
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 2.4316049721
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 5.2010091137
MESH:D014581 Urticaria Acetaminophen 3.5810982225
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018