Annotation Detail for ANKLE2
Basic Information
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| Gene Symbol: | ANKLE2 ( FLJ22280,FLJ36132,KIAA0692,LEMD7 ) |
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| Gene Full Name: | ankyrin repeat and LEM domain containing 2 |
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| Band: | 12q24.33 |
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| Quick Links | Entrez ID:23141; OMIM: NA; Uniprot ID:ANKL2_HUMAN; ENSEMBL ID: ENSG00000176915; HGNC ID: 29101 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D016572 |
Cyclosporine |
Cyclosporine results in increased expression of ANKLE2 mRNA | increases expression | 20106945
|
| C025643 |
vinclozolin |
vinclozolin results in decreased expression of ANKLE2 mRNA | decreases expression | 18042343
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D001008 |
Anxiety Disorders |
|
vinclozolin |
4.05 | 19015723 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
Cyclosporine |
2.85 | 12371664 |
| MESH:D002779 |
Cholestasis |
|
Cyclosporine |
3.28 | 19486331 |
| MESH:D003456 |
Cryptorchidism |
|
vinclozolin |
5.02 | 14966744 |
| MESH:D005234 |
Fatty Liver |
|
Cyclosporine |
3.40 | 19224547 |
| MESH:D005355 |
Fibrosis |
|
Cyclosporine |
3.90 | 12168785 12639820 |
| MESH:D030342 |
Genetic Diseases, Inborn |
|
vinclozolin |
5.82 | 16973722 |
| MESH:D005832 |
Genital Diseases, Male |
|
vinclozolin |
6.37 | 16417039 |
| MESH:D005885 |
Gingival Hyperplasia |
|
Cyclosporine |
5.11 | 8708960 |
| MESH:D006457 |
Hemoglobinuria, Paroxysmal |
|
Cyclosporine |
5.31 | 15720958 |
| MESH:D006973 |
Hypertension |
|
Cyclosporine |
2.24 | 10903974 |
| MESH:D007248 |
Infertility, Male |
|
vinclozolin |
3.35 | 16467254 |
| MESH:D007638 |
Keratoconjunctivitis Sicca |
|
Cyclosporine |
5.51 | 15604871 |
| MESH:D007674 |
Kidney Diseases |
|
Cyclosporine |
2.58 | 18776723 10903974 8314463 |
| MESH:D007680 |
Kidney Neoplasms |
|
Cyclosporine |
3.17 | 12371664 |
| MESH:D007984 |
Leydig Cell Tumor |
|
vinclozolin |
5.62 | 16417039 |
| MESH:D008664 |
Metal Metabolism, Inborn Errors |
|
Cyclosporine |
5.86 | 16801185 |
| MESH:D009402 |
Nephrosis, Lipoid |
|
Cyclosporine |
5.51 | 17954296 |
| MESH:D009404 |
Nephrotic Syndrome |
|
Cyclosporine |
3.75 | 19348381 18481113 |
| MESH:D011230 |
Precancerous Conditions |
|
Cyclosporine |
3.69 | 12371664 |
| MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
vinclozolin |
4.78 | 18042343 18220299 19015723 |
| MESH:D011469 |
Prostatic Diseases |
|
vinclozolin |
5.82 | 18220299 |
| MESH:D011472 |
Prostatitis |
|
vinclozolin |
5.82 | 18629315 |
| MESH:D011565 |
Psoriasis |
|
Cyclosporine |
2.35 | 16882103 |
| MESH:D014605 |
Uveitis |
|
Cyclosporine |
5.05 | 1336536 |
| MESH:D014985 |
Xerophthalmia |
|
Cyclosporine |
5.51 | 17120751 |
PharmGKB Accession:PA162376532
| Releated disease ID |
Related disease Name |
| PA446155 | Precursor Cell Lymphoblastic Leukemia-Lymphoma |
Related Pathway Information