AutismKB 2.0

Annotation Detail for GRAMD4


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Basic Information Top
Gene Symbol:GRAMD4 ( DIP,KIAA0767,MGC149847,MGC90497,dA59H18.1,dJ439F8.1 )
Gene Full Name: GRAM domain containing 4
Band: 22q13.31
Quick LinksEntrez ID:23151; OMIM: NA; Uniprot ID:GRAM4_HUMAN; ENSEMBL ID: ENSG00000075240; HGNC ID: 29113
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of GRAMD4 mRNAdecreases expression 20106945
D002117 Calcitriol Calcitriol results in increased expression of GRAMD4 mRNAincreases expression 16002434
D018038 Sodium Selenite Sodium Selenite results in decreased expression of GRAMD4 mRNAdecreases expression 18175754
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0620464547 20127859
MESH:D000236 Adenoma Benzo(a)pyrene 2.886695378
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.7319183758
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.1920146248 17474063
MESH:D001943 Breast Neoplasms Calcitriol 2.1911237771
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 5.0220419170
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 5.0211237771
MESH:D019457 Chromosome Breakage Sodium Selenite 5.4115894690
MESH:D003920 Diabetes Mellitus Sodium Selenite 4.1916285004
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 2.3715131321
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 4.5215138306
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0916530937
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8520471113
MESH:D007333 Insulin Resistance Sodium Selenite 3.5414714311
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 2.1720195826 21137059
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 1.5720869020 18569708 20135361 20464547 6695378 18816296 20064080 17053015 18520028
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 4.5914737004
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.5316381670
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3511141357
MESH:D011470 Prostatic Hyperplasia Calcitriol 5.5215572423
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.5317292933
MESH:D011471 Prostatic Neoplasms Calcitriol 2.5316289102 15754350 16644109 18247401 12479363
MESH:D011471 Prostatic Neoplasms Sodium Selenite 2.5318760546
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.5410029692 19755658
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.562093021 20155912
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.3117053015
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA128394606
  • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018