Annotation Detail for CIC
Basic Information Top
| Gene Symbol: | CIC ( KIAA0306 ) |
|---|---|
| Gene Full Name: | capicua homolog (Drosophila) |
| Band: | 19q13.2 |
| Quick Links | Entrez ID:23152; OMIM: 612082; Uniprot ID:CIC_HUMAN; ENSEMBL ID: ENSG00000079432; HGNC ID: 14214 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of CIC mRNA | affects expression | 17562736 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in decreased expression of CIC mRNA | decreases expression | 17484886 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000799 | Angioedema | Acetaminophen | 4.91 | 10982225 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D002252 | Carbon Tetrachloride Poisoning | Carbon Tetrachloride | 4.54 | 18705752 16192424 15721981 16011737 15700767 10355542 15673190 16050911 16227642 3786805 16097048 16124888 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 3.01 | 3084413 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Carbon Tetrachloride | 3.01 | 18788625 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.83 | 10977129 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 4.11 | 16081117 16781746 10915739 12392966 11287661 11461765 19739265 10774834 16109766 12153990 11421492 14550746 17522070 10663392 17906064 18071297 15968718 16485898 19420014 11743745 16227642 19370779 19085960 12705907 11834606 19416960 19164858 11739529 14986274 17562736 16177239 14725611 12594235 12540782 19923254 11529661 12958197 16393943 15619225 18713872 2444490 | |
| MESH:D056486 | Drug-Induced Liver Injury | Carbon Tetrachloride | 4.11 | 7440962 10092053 19085960 10915739 15968718 15027814 11566570 6884620 19336974 7179309 15998439 16227642 3786805 9327722 7120509 2869522 3732212 4309450 6623471 21278145 16177239 17522070 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 5.17 | 19426721 | |
| MESH:D005234 | Fatty Liver | Carbon Tetrachloride | 3.72 | 16239168 12631006 17595544 12795759 15959796 61145 16045604 19224547 | |
| MESH:D005355 | Fibrosis | Carbon Tetrachloride | 4.22 | 18705752 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.74 | 16983495 | |
| MESH:D006505 | Hepatitis | Carbon Tetrachloride | 4.27 | 19900420 19110552 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.11 | 16870215 | |
| MESH:D006932 | Hyperbilirubinemia | Carbon Tetrachloride | 5.42 | 16899240 | |
| MESH:D006975 | Hypertension, Portal | Carbon Tetrachloride | 4.85 | 15338365 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.44 | 12587719 15629191 | |
| MESH:D008103 | Liver Cirrhosis | Carbon Tetrachloride | 3.04 | 16943688 16221502 11903743 17174718 11408273 17157831 17334410 21278145 16239168 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Carbon Tetrachloride | 1.76 | 16027843 12666154 15996030 18205269 12958196 15876570 16011737 12445421 18705752 17525996 15057751 15818738 16116963 18006644 17631135 18054572 16192424 17823541 12632512 12898905 15052691 12667390 18317297 17761835 17944888 17714472 18187930 18251166 18339082 12546737 15362042 17698563 17766677 12389079 17976157 18376398 18263696 18412020 15123356 10355542 18156304 15370692 18166357 17721639 18481824 12632514 12741479 14716496 15893842 18279442 15650968 15730626 12586293 15338365 18429990 16248980 15959796 12445418 17565644 17557913 18472332 14620537 17869086 14512876 20821823 18418968 16136751 17640975 15931870 18210741 17481882 18395914 14716833 13678700 12609069 15673190 14748882 17805973 11481614 17708605 18420326 15925388 18395095 14724832 16097048 17922224 18472094 17900296 18277467 16033810 16638106 12649538 16015684 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 4.21 | 12587719 12969438 11587558 16611625 19460945 19014921 16610002 19784758 | |
| MESH:D008107 | Liver Diseases | Carbon Tetrachloride | 4.21 | 15720792 16964402 16246199 17285989 15830285 | |
| MESH:D017093 | Liver Failure | Carbon Tetrachloride | 4.93 | 15123358 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 11.14 | 16871587 17185352 | |
| MESH:D017114 | Liver Failure, Acute | Carbon Tetrachloride | 11.14 | 16899240 14706259 | |
| MESH:D008113 | Liver Neoplasms | Carbon Tetrachloride | 2.36 | 19294768 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Carbon Tetrachloride | 2.89 | 12014681 15583823 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.33 | 19513568 | |
| MESH:D008607 | Mental Retardation | marker/mechanism | 21076407 | ||
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.31 | 18514411 | |
| MESH:D010146 | Pain | Acetaminophen | 2.82 | 16870215 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.58 | 10982225 |
| No data |