AutismKB 2.0

Annotation Detail for NUP205


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Basic Information Top
Gene Symbol:NUP205 ( C7orf14 )
Gene Full Name: nucleoporin 205kDa
Band: 7q33
Quick LinksEntrez ID:23165; OMIM: NA; Uniprot ID:NU205_HUMAN; ENSEMBL ID: ENSG00000155561; HGNC ID: 18658
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Metabolism of carbohydrates
Transmembrane transport of small molecules
HIV Infection
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of NUP205 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of NUP205 mRNAaffects expression 21346803
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of NUP205 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of NUP205 mRNAaffects expression 17562736
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of NUP205 mRNAdecreases expression 15336504
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 4.497525203
MESH:D000799 Angioedema Acetaminophen 4.4510982225
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 4.7616705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 4.7616705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.763084413
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 8.0514694615
MESH:D002386 Cataract Acetaminophen 8.0510977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 3.006135515
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 4.4915095906
MESH:D003490 Cyanosis 2,4-dinitrotoluene 12.5618551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 12.5618551238
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 9.7218551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 9.7218551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 9.7221346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 9.7212392966 11287661 19420014 16081117 11743745 12705907 16485898 19739265 15619225 15968718 10663392 17906064 19370779 11834606 17562736 18713872 17522070 16781746 16393943 14725611 2444490 19416960 11421492 18071297 11739529 11461765 19164858 16227642 11529661 14986274 12540782 19085960 19923254 16109766 12594235 10915739 14550746 12153990 12958197 16177239 10774834
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.7119426721
MESH:D005756 Gastritis Acetaminophen 4.2916983495
MESH:D006930 Hyperalgesia Acetaminophen 2.9916870215
MESH:D007674 Kidney Diseases Acetaminophen 2.3812587719 15629191
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 8.3916705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 8.3916705839
MESH:D008107 Liver Diseases Acetaminophen 1.6916611625 16610002 11587558 12969438 19460945 19784758 12587719 19014921
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5816871587 17185352
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 2.257678174
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.742876786 6135515 2876784
MESH:D008546 Melanoma, Experimental Acetaminophen 4.0519513568
MESH:D009336 Necrosis 2,4-dinitrotoluene 12.2118551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 12.217678174 18551238
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1818514411
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 17.2612819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 17.2616049721
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 17.2614694615
MESH:D010146 Pain Acetaminophen 2.6916870215
MESH:D012640 Seizures 2,4-dinitrotoluene 6.6518551238
MESH:D012640 Seizures 2,6-dinitrotoluene 6.6518551238
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 2.838532709
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 5.3916049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 5.3916049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 13.8610091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 13.8610091137
MESH:D014581 Urticaria Acetaminophen 3.3810982225
Pathway ID Pathway Name
REACT:6185 HIV Infection
REACT:474 Metabolism of carbohydrates
KEGG:03013 RNA transport
REACT:15518 Transmembrane transport of small molecules
Pharmacogenomics Knowledge Base Top
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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