AutismKB 2.0

Annotation Detail for ACSBG1


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Basic Information Top
Gene Symbol:ACSBG1 ( BG1,BGM,FLJ30320,GR-LACS,KIAA0631,MGC14352,hBG1,hsBG )
Gene Full Name: acyl-CoA synthetase bubblegum family member 1
Band: 15q25.1
Quick LinksEntrez ID:23205; OMIM: NA; Uniprot ID:ACBG1_HUMAN; ENSEMBL ID: ENSG00000103740; HGNC ID: 29567
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PWY-6000gamma-linolenate biosynthesis II (animals)
PWY-5972stearate biosynthesis I (animals)
FAO-PWYfatty acid beta-oxidation I
PWY-5143fatty acid activation
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No data
No data
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No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C404910 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [FSHB protein affects the expression of ACSBG1 mRNA]affects expression|affects reaction 19414516
D000643 Ammonium Chloride Ammonium Chloride affects the expression of ACSBG1 mRNAaffects expression 16483693
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of ACSBG1 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of ACSBG1 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of ACSBG1 mRNAaffects expression 17351261
D008767 Methylmercury Compounds Methylmercury Compounds affects the expression of ACSBG1 mRNAaffects expression 16966085
D013629 Tamoxifen Tamoxifen affects the expression of ACSBG1 mRNAaffects expression 17555576
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 5.1614745880
MESH:D000138 Acidosis Ammonium Chloride 4.1018287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.5517505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8814692618
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.9511256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8615885639
MESH:D001943 Breast Neoplasms Tamoxifen 2.1717049068 19142967 19189210 19155303 17893378 20005174 19487384 20135344 18815881 19103187 20390343 16202921 20544844 11161223 15668708 18425577 17261762 18629630 19011961 18351453 19221464 18984771 19189212 18855134 19084267 19115204 19288272 20065188 15565566 16273361 21138602 20859285 19200415 21152245 17242785 19059307 19289846 16873071 19066611 17440819 19244106 16818667 19410462 18821012 18997820
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.9919066611
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 1.8516924424
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.9617572228
MESH:D002779 Cholestasis Ethinyl Estradiol 3.1311677210 15861022 17681005 17110522 16105132 17333356 16919318
MESH:D003704 Dementia Methylmercury Compounds 5.3716140633
MESH:D003711 Demyelinating Diseases Tamoxifen 4.8519031437
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.8019279558
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 10.4512538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 10.4519031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 3.2620544844 17893378 19155303 16202921
MESH:D005234 Fatty Liver Ethinyl Estradiol 8.9615345470
MESH:D005234 Fatty Liver Tamoxifen 8.9614986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.4316709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 5.0714745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.7219069698
MESH:D007021 Hypospadias Ethinyl Estradiol 4.2916569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.8712013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.7117937319
MESH:D007249 Inflammation Tamoxifen 2.5119457130
MESH:D007680 Kidney Neoplasms Tamoxifen 3.3518625569
MESH:D008064 Lipidoses Tamoxifen 3.4015342952 17567588
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 1.7518564211
MESH:D008113 Liver Neoplasms Tamoxifen 2.3216684651
MESH:D008175 Lung Neoplasms Tamoxifen 1.7418625569
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 4.3019428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.8316827153 19196722 19196723 11731420 14580682
MESH:D020149 Manganese Poisoning Tamoxifen 5.1619453300
MESH:D008545 Melanoma Tamoxifen 1.9219393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.7215990972
MESH:D008569 Memory Disorders Methylmercury Compounds 5.3518436314
MESH:D009069 Movement Disorders Methylmercury Compounds 5.7318436314
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.6619393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.6019410462
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.6119189210 19200415 19196722
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.0911578682
MESH:D011297 Prenatal Exposure Delayed Effects Methylmercury Compounds 5.5218436314
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.0915067354
MESH:D011537 Pruritus Ethinyl Estradiol 3.8516919318 15861022
MESH:D013088 Spermatocele Ethinyl Estradiol 13.6916709447
MESH:D013088 Spermatocele Tamoxifen 13.6916709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.5819457130
MESH:D019851 Thrombophilia Ethinyl Estradiol 4.0211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.4815669648
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 2.468653321 17572228 16712894
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.7414692618
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.9115869587 14671159
Pathway ID Pathway Name
KEGG:04920 Adipocytokine signaling pathway
KEGG:00071 Fatty acid metabolism
KEGG:01100 Metabolic pathways
KEGG:03320 PPAR signaling pathway
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB08326 - 2-(6-HYDROXY-1,3-BENZOTHIAZOL-2-YL)-1,3-THIAZOL-4(5H)-ONE
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018