Annotation Detail for NBEAL2
Basic Information
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| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C016403 |
2,4-dinitrotoluene |
2,4-dinitrotoluene affects the expression of NBEAL2 mRNA | affects expression | 21346803
|
| C023514 |
2,6-dinitrotoluene |
2,6-dinitrotoluene affects the expression of NBEAL2 mRNA | affects expression | 21346803
|
| D003907 |
Dexamethasone |
Dexamethasone results in increased expression of NBEAL2 mRNA | increases expression | 12782123
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D001169 |
Arthritis, Experimental |
|
Dexamethasone |
3.78 | 17659584 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,4-dinitrotoluene |
3.11 | 16705839 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,6-dinitrotoluene |
3.11 | 16705839 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
2,6-dinitrotoluene |
3.06 | 6135515 |
| MESH:D003110 |
Colonic Neoplasms |
|
Dexamethasone |
2.55 | 15824018 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Dexamethasone |
2.29 | 17728286 |
| MESH:D003490 |
Cyanosis |
|
2,4-dinitrotoluene |
13.16 | 18551238 |
| MESH:D003490 |
Cyanosis |
|
2,6-dinitrotoluene |
13.16 | 18551238 |
| MESH:D017449 |
Dermatitis, Allergic Contact |
|
Dexamethasone |
4.05 | 12438553 |
| MESH:D003967 |
Diarrhea |
|
Dexamethasone |
4.28 | 7237001 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,4-dinitrotoluene |
4.19 | 18551238 21346803 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,6-dinitrotoluene |
4.19 | 21346803 18551238 |
| MESH:D004485 |
Eczema |
|
Dexamethasone |
5.04 | 12438553 |
| MESH:D004487 |
Edema |
|
Dexamethasone |
3.88 | 19703484 |
| MESH:D006548 |
Hernia, Diaphragmatic |
|
Dexamethasone |
3.19 | 7520565 |
| MESH:D006973 |
Hypertension |
|
Dexamethasone |
3.06 | 17042910 |
| MESH:D007249 |
Inflammation |
|
Dexamethasone |
3.07 | 8960868 11099482 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,4-dinitrotoluene |
8.67 | 16705839 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,6-dinitrotoluene |
8.67 | 16705839 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Dexamethasone |
2.27 | 16718785 |
| MESH:D008113 |
Liver Neoplasms |
|
2,6-dinitrotoluene |
2.28 | 7678174 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
2,6-dinitrotoluene |
2.79 | 2876784 6135515 2876786 |
| MESH:D008175 |
Lung Neoplasms |
|
Dexamethasone |
2.27 | 11195469 15824018 |
| MESH:D009101 |
Multiple Myeloma |
|
Dexamethasone |
3.81 | 15867202 15744524 16118317 |
| MESH:D009190 |
Myelodysplastic Syndromes |
|
Dexamethasone |
3.76 | 9809623 |
| MESH:D009336 |
Necrosis |
|
2,4-dinitrotoluene |
12.96 | 18551238 |
| MESH:D009336 |
Necrosis |
|
2,6-dinitrotoluene |
12.96 | 18551238 7678174 |
| MESH:D009784 |
Occupational Diseases |
|
2,4-dinitrotoluene |
10.41 | 16049721 12819281 |
| MESH:D009784 |
Occupational Diseases |
|
2,6-dinitrotoluene |
10.41 | 16049721 |
| MESH:D054198 |
Precursor Cell Lymphoblastic Leukemia-Lymphoma |
|
Dexamethasone |
3.76 | 21297632 |
| MESH:D012128 |
Respiratory Distress Syndrome, Adult |
|
Dexamethasone |
4.54 | 18379247 11700416 |
| MESH:D012640 |
Seizures |
|
2,4-dinitrotoluene |
6.84 | 18551238 |
| MESH:D012640 |
Seizures |
|
2,6-dinitrotoluene |
6.84 | 18551238 |
| MESH:D013272 |
Stomach Diseases |
|
Dexamethasone |
5.06 | 15472012 |
| MESH:D013276 |
Stomach Ulcer |
|
Dexamethasone |
3.96 | 15138204 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,4-dinitrotoluene |
5.48 | 16049721 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,6-dinitrotoluene |
5.48 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,4-dinitrotoluene |
14.60 | 10091137 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,6-dinitrotoluene |
14.60 | 10091137 |
| MESH:D014605 |
Uveitis |
|
Dexamethasone |
5.68 | 1336536 |
PharmGKB Accession:PA128394612
| Releated disease ID |
Related disease Name |
| PA446155 | Precursor Cell Lymphoblastic Leukemia-Lymphoma |
| Releated drug ID |
Related drug Name |
| PA449014 | cisplatin |
Related Pathway Information