Annotation Detail for FBXO28
Basic Information
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| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C016403 |
2,4-dinitrotoluene |
2,4-dinitrotoluene affects the expression of FBXO28 mRNA | affects expression | 21346803
|
| D013196 |
Dihydrotestosterone |
Dihydrotestosterone results in decreased expression of FBXO28 mRNA | decreases expression | 16631469
|
| D012643 |
Selenium |
[Selenium co-treated with Vitamin E] results in increased expression of FBXO28 mRNA | affects cotreatment|increases expression | 19244175
|
| D012643 |
Selenium |
Selenium results in decreased expression of FBXO28 mRNA | decreases expression | 19244175
|
| D014810 |
Vitamin E |
[Selenium co-treated with Vitamin E] results in increased expression of FBXO28 mRNA | affects cotreatment|increases expression | 19244175
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D002252 |
Carbon Tetrachloride Poisoning |
|
Vitamin E |
4.49 | 16050911 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,4-dinitrotoluene |
1.79 | 16705839 |
| MESH:D003092 |
Colitis |
|
Selenium |
4.34 | 17936198 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Vitamin E |
1.93 | 19769572 |
| MESH:D003490 |
Cyanosis |
|
2,4-dinitrotoluene |
4.58 | 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,4-dinitrotoluene |
4.24 | 18551238 21346803 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Selenium |
4.24 | 15131321 |
| MESH:C538011 |
Eales disease |
|
Vitamin E |
5.43 | 9068938 |
| MESH:D006330 |
Heart Defects, Congenital |
|
Vitamin E |
3.17 | 16080930 |
| MESH:D006333 |
Heart Failure |
|
Selenium |
3.29 | 17162251 |
| MESH:D006548 |
Hernia, Diaphragmatic |
|
Vitamin E |
2.81 | 16490937 16863852 |
| MESH:D019584 |
Hot Flashes |
|
Vitamin E |
4.69 | 14716179 |
| MESH:D007251 |
Influenza, Human |
|
Selenium |
13.50 | 16624496 |
| MESH:D007251 |
Influenza, Human |
|
Vitamin E |
13.50 | 16624496 |
| MESH:D007674 |
Kidney Diseases |
|
Vitamin E |
3.00 | 12488133 |
| MESH:D007676 |
Kidney Failure, Chronic |
|
Selenium |
4.31 | 16518626 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,4-dinitrotoluene |
3.32 | 16705839 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Vitamin E |
1.91 | 16169303 |
| MESH:D008171 |
Lung Diseases |
|
Vitamin E |
3.43 | 16863852 |
| MESH:D008175 |
Lung Neoplasms |
|
Vitamin E |
1.90 | 11062179 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Selenium |
2.99 | 15318939 |
| MESH:D008654 |
Mesothelioma |
|
Selenium |
2.92 | 15107826 |
| MESH:D009336 |
Necrosis |
|
2,4-dinitrotoluene |
4.49 | 18551238 |
| MESH:D009784 |
Occupational Diseases |
|
2,4-dinitrotoluene |
3.82 | 16049721 12819281 |
| MESH:D010954 |
Plasmacytoma |
|
Selenium |
5.61 | 15087411 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Vitamin E |
3.24 | 15084515 |
| MESH:D012640 |
Seizures |
|
2,4-dinitrotoluene |
2.79 | 18551238 |
| MESH:D012871 |
Skin Diseases |
|
Vitamin E |
2.52 | 18709164 |
| MESH:D020521 |
Stroke |
|
Vitamin E |
3.84 | 16517955 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,4-dinitrotoluene |
2.41 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,4-dinitrotoluene |
4.95 | 10091137 |
Related Pathway Information