Gene Symbol:	PHLPP1 ( MGC161555,PHLPP,PLEKHE1,SCOP )
Gene Full Name:	PH domain and leucine rich repeat protein phosphatase 1
Band:	18q21.33
Quick Links	Entrez ID:23239; OMIM: 609396; Uniprot ID:PHLP1_HUMAN; ENSEMBL ID: ENSG00000081913; HGNC ID: 20610
Relate to Another Database:	SFARIGene; denovo-db

Chemical ID	Chemical Name	Interaction	Interaction Action	Publication
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of PHLPP1 mRNA	decreases expression	20064835
D008694	Methamphetamine	Methamphetamine affects the expression of PHLPP1 mRNA	affects expression	15950759
D008694	Methamphetamine	Methamphetamine results in increased expression of PHLPP1 protein	increases expression	15542705 15950759

Disease ID	Disease Name	Inference Chemical Name	Inference Score	Publication
MESH:D000230	Adenocarcinoma	Benzo(a)pyrene	2.07	20464547 20127859
MESH:D000236	Adenoma	Benzo(a)pyrene	2.90	6695378
MESH:D017544	Aortic Aneurysm, Abdominal	Benzo(a)pyrene	4.84	19183758
MESH:D001943	Breast Neoplasms	Benzo(a)pyrene	1.98	20146248 17474063
MESH:D002294	Carcinoma, Squamous Cell	Benzo(a)pyrene	2.15	20419170
MESH:D004938	Esophageal Neoplasms	Benzo(a)pyrene	2.09	16530937
MESH:D006330	Heart Defects, Congenital	Benzo(a)pyrene	2.87	20471113
MESH:D006948	Hyperkinesis	Methamphetamine	6.39	17658665
MESH:D008113	Liver Neoplasms	Benzo(a)pyrene	2.18	20195826 21137059
MESH:D008175	Lung Neoplasms	Benzo(a)pyrene	1.57	20135361 20464547 20064080 18816296 20869020 18520028 6695378 17053015 18569708
MESH:D009062	Mouth Neoplasms	Benzo(a)pyrene	3.57	16381670
MESH:D009369	Neoplasms	Benzo(a)pyrene	2.36	11141357
MESH:D011471	Prostatic Neoplasms	Benzo(a)pyrene	2.90	17292933
MESH:D012878	Skin Neoplasms	Benzo(a)pyrene	2.55	19755658 10029692
MESH:D013274	Stomach Neoplasms	Benzo(a)pyrene	1.56	2093021 20155912
MESH:D001749	Urinary Bladder Neoplasms	Benzo(a)pyrene	2.32	17053015

AutismKB 2.0

Annotation Detail for PHLPP1