Annotation Detail for PACS2
Basic Information Top
| Gene Symbol: | PACS2 ( FLJ25488,KIAA0602,PACS1L ) |
|---|---|
| Gene Full Name: | phosphofurin acidic cluster sorting protein 2 |
| Band: | 14q32.33 |
| Quick Links | Entrez ID:23241; OMIM: 610423; Uniprot ID:PACS2_HUMAN; ENSEMBL ID: ENSG00000179364; HGNC ID: 23794 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of PACS2 mRNA | affects expression | 17562736 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in decreased expression of PACS2 mRNA | decreases expression | 20064835 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000230 | Adenocarcinoma | Benzo(a)pyrene | 2.07 | 20127859 20464547 | |
| MESH:D000236 | Adenoma | Benzo(a)pyrene | 2.90 | 6695378 | |
| MESH:D000799 | Angioedema | Acetaminophen | 4.91 | 10982225 | |
| MESH:D017544 | Aortic Aneurysm, Abdominal | Benzo(a)pyrene | 4.84 | 19183758 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D001943 | Breast Neoplasms | Benzo(a)pyrene | 1.98 | 17474063 20146248 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Benzo(a)pyrene | 2.15 | 20419170 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.83 | 10977129 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.68 | 11421492 10915739 16393943 15619225 12958197 11529661 19085960 18713872 12705907 10774834 19370779 19420014 15968718 12594235 16081117 19164858 19739265 11739529 17522070 14550746 16485898 2444490 16109766 12153990 16177239 19923254 16781746 12540782 14725611 17906064 11461765 18071297 16227642 10663392 11834606 11287661 17562736 11743745 19416960 12392966 14986274 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 5.17 | 19426721 | |
| MESH:D004938 | Esophageal Neoplasms | Benzo(a)pyrene | 2.09 | 16530937 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.74 | 16983495 | |
| MESH:D006330 | Heart Defects, Congenital | Benzo(a)pyrene | 2.87 | 20471113 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.11 | 16870215 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.44 | 15629191 12587719 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.71 | 12969438 12587719 19460945 19784758 19014921 11587558 16611625 16610002 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.74 | 16871587 17185352 | |
| MESH:D008113 | Liver Neoplasms | Benzo(a)pyrene | 2.18 | 20195826 21137059 | |
| MESH:D008175 | Lung Neoplasms | Benzo(a)pyrene | 1.57 | 17053015 20464547 20135361 18816296 18520028 20064080 20869020 18569708 6695378 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.33 | 19513568 | |
| MESH:D009062 | Mouth Neoplasms | Benzo(a)pyrene | 3.57 | 16381670 | |
| MESH:D009369 | Neoplasms | Benzo(a)pyrene | 2.36 | 11141357 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.31 | 18514411 | |
| MESH:D010146 | Pain | Acetaminophen | 2.82 | 16870215 | |
| MESH:D011471 | Prostatic Neoplasms | Benzo(a)pyrene | 2.90 | 17292933 | |
| MESH:D012878 | Skin Neoplasms | Benzo(a)pyrene | 2.55 | 19755658 10029692 | |
| MESH:D013274 | Stomach Neoplasms | Benzo(a)pyrene | 1.56 | 20155912 2093021 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Benzo(a)pyrene | 2.32 | 17053015 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.58 | 10982225 |
| No data |