Annotation Detail for PDS5A
Basic Information
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| Gene Symbol: | PDS5A ( DKFZp686B19246,FLJ41012,KIAA0648,MGC131948,MGC161503,SCC-112 ) |
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| Gene Full Name: | PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae) |
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| Band: | 4p14 |
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| Quick Links | Entrez ID:23244; OMIM: 613200; Uniprot ID:PDS5A_HUMAN; ENSEMBL ID: ENSG00000121892; HGNC ID: 29088 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D015123 |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of PDS5A mRNA | decreases expression | 19150397
|
| D016685 |
Mitomycin |
PDS5A protein affects the susceptibility to Mitomycin | affects response to substance | 16217747
|
| C006253 |
pirinixic acid |
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of PDS5A mRNA | affects binding|increases activity|increases expression | 19710929
|
| D011374 |
Progesterone |
Progesterone results in increased expression of PDS5A mRNA | increases expression | 18070364
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.58 | 18653653 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
4.11 | 16434500 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.57 | 19483382 |
| MESH:D020201 |
Brain Hemorrhage, Traumatic |
|
Progesterone |
6.06 | 17868700 |
| MESH:D001930 |
Brain Injuries |
|
Progesterone |
4.82 | 15665606 15845082 15380490 |
| MESH:D001943 |
Breast Neoplasms |
|
Progesterone |
2.41 | 15562024 16175315 17614352 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
2.98 | 20889678 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
3.12 | 19176532 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.57 | 18249437 |
| MESH:D003929 |
Diabetic Neuropathies |
|
Progesterone |
5.05 | 17187935 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
2.90 | 12083418 |
| MESH:D004681 |
Encephalomyelitis, Autoimmune, Experimental |
|
Progesterone |
4.28 | 17692515 |
| MESH:D004715 |
Endometriosis |
|
Progesterone |
4.16 | 16134523 |
| MESH:D004938 |
Esophageal Neoplasms |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
2.15 | 20426865 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
3.19 | 19236843 20131406 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.76 | 20558911 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.55 | 18467677 16221962 19176532 19772884 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.58 | 20558911 |
| MESH:D020244 |
Infarction, Middle Cerebral Artery |
|
Progesterone |
4.96 | 15869954 |
| MESH:D007249 |
Inflammation |
|
Progesterone |
2.77 | 15869954 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.87 | 16306350 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
| MESH:D008113 |
Liver Neoplasms |
|
Mitomycin |
5.22 | 15113037 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
5.22 | 16377806 15890375 20007298 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Progesterone |
3.10 | 17203775 11408345 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
4.07 | 16239165 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.27 | 19151258 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.25 | 16411023 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.11 | 17405874 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
1.88 | 20558911 |
| MESH:D010051 |
Ovarian Neoplasms |
|
Progesterone |
2.62 | 16525653 17393432 |
| MESH:D010190 |
Pancreatic Neoplasms |
|
Mitomycin |
3.56 | 15113037 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.55 | 19058328 |
| MESH:D012468 |
Salivary Gland Neoplasms |
|
Progesterone |
2.96 | 18045962 |
| MESH:D013119 |
Spinal Cord Injuries |
|
Progesterone |
4.91 | 15862959 16503802 |
Related Pathway Information