AutismKB 2.0

Annotation Detail for ZC3H7B


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Basic Information Top
Gene Symbol:ZC3H7B ( DKFZp434K0920,FLJ13787,KIAA1031,RoXaN )
Gene Full Name: zinc finger CCCH-type containing 7B
Band: 22q13.2
Quick LinksEntrez ID:23264; OMIM: NA; Uniprot ID:Z3H7B_HUMAN; ENSEMBL ID: ENSG00000100403; HGNC ID: 30869
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of ZC3H7B mRNAaffects expression 21346803
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of ZC3H7B mRNAaffects expression 21346803
C006632 arsenic trioxide arsenic trioxide results in increased expression of ZC3H7B mRNAincreases expression 20458559
D007657 Ketone Bodies Ketone Bodies results in increased expression of ZC3H7B mRNAincreases expression 16807920
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 4.587525203
MESH:D000230 Adenocarcinoma arsenic trioxide 2.3619825857 11798837
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 4.1016206674
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.7911589617
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 3.1716705839
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 3.1715553829 15073043 11135700 16217749 14691202
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.6019014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.5112490120
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 3.8414694615
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 3.036135515
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 4.5315095906
MESH:D023903 Coronary Restenosis arsenic trioxide 4.6912609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 1.8910525206
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.5818551238
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.5615213294
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 4.4121346803 18551238
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 4.4121346803
MESH:D004938 Esophageal Neoplasms arsenic trioxide 2.3812903497
MESH:D005234 Fatty Liver arsenic trioxide 3.7115073043
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.7716904648
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 3.3216705839
MESH:D007938 Leukemia arsenic trioxide 3.0015070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 4.2217077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.9416972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.7214633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 4.1919077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1920471514 19850784 17050201 16467208 16968895
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.4616112521 16330433 16966277 15336539 16823087 17107899 19225113 17217047 9834237 12018890 19075265 12712474 17869043 17712046 16891316 19642359 11468182 15748426 15213294 15622746 17649720 16331271 12679006 19035177 11161223
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.8616882451
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 5.017678174
MESH:D008113 Liver Neoplasms arsenic trioxide 5.0114682389
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 6.736135515 2876786 2876784
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 6.7320377131
MESH:D008133 Long QT Syndrome arsenic trioxide 3.6615213294
MESH:D008175 Lung Neoplasms arsenic trioxide 1.8719825857 11798837
MESH:D009101 Multiple Myeloma arsenic trioxide 3.3811468182 14977855 19549372 15949261 19417148
MESH:D009182 Mycosis Fungoides arsenic trioxide 5.4018349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.3416105982 16882451
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.497678174 18551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.4716624393
MESH:D009436 Neural Tube Defects arsenic trioxide 3.3610525206
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 10.4716049721
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 10.4714694615
MESH:D010051 Ovarian Neoplasms arsenic trioxide 2.5016624393 12452020 19769630
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.6315580305
MESH:D010235 Paraganglioma arsenic trioxide 4.6319927285
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.2119131511
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.4716646077
MESH:D012640 Seizures 2,6-dinitrotoluene 2.7918551238
MESH:D013274 Stomach Neoplasms arsenic trioxide 1.8617007042
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.3919014326
MESH:D016171 Torsades de Pointes arsenic trioxide 4.5915213294
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 5.5116049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 5.5112845720 20435036 11780464 12973940
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.9510091137
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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