AutismKB 2.0

Annotation Detail for PHF15


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PHF15 ( JADE2,KIAA0239 )
Gene Full Name: PHD finger protein 15
Band: 5q31.1
Quick LinksEntrez ID:23338; OMIM: 610515; Uniprot ID:JADE2_HUMAN; ENSEMBL ID: ENSG00000043143; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of PHF15 mRNAdecreases expression 19150397
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of PHF15 mRNAaffects expression 17484886
C058305 phenethyl isothiocyanate phenethyl isothiocyanate results in decreased expression of PHF15 mRNAdecreases expression 17616710
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 4.4315673190 16050911 16011737 10355542 15721981 18705752 16227642 3786805 15700767 16124888 16097048 16192424
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 1.8618788625
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 3.0120889678
MESH:D003093 Colitis, Ulcerative phenethyl isothiocyanate 3.7620423518
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 2.136623471 16227642 19085960 10092053 16177239 21278145 3732212 4309450 7440962 2869522 7179309 15027814 3786805 9327722 15968718 17522070 11566570 10915739 15998439 19336974 7120509 6884620
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1520426865
MESH:D005234 Fatty Liver Carbon Tetrachloride 3.6519224547 17595544 12631006 16239168 61145 15959796 12795759 16045604
MESH:D005355 Fibrosis Carbon Tetrachloride 4.1018705752
MESH:D006505 Hepatitis Carbon Tetrachloride 4.1819900420 19110552
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 5.2716899240
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.7415338365
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 3.0211408273 16239168 16943688 17174718 17157831 17334410 11903743 21278145 16221502
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 1.7512609069 18006644 16136751 12667390 15650968 14620537 15362042 17557913 17976157 18395914 17869086 18412020 16011737 12389079 14716833 18277467 15893842 17698563 18166357 17761835 17565644 18472332 16116963 15818738 16033810 10355542 12958196 18418968 18317297 17721639 18054572 12546737 15925388 17640975 14724832 15338365 17766677 15876570 20821823 12666154 12586293 18205269 16638106 16248980 16097048 15730626 18472094 14512876 18429990 14748882 17900296 15370692 18481824 18279442 11481614 14716496 17922224 13678700 12632512 16015684 17481882 17714472 16192424 17708605 15052691 12445421 17631135 17805973 17944888 12632514 12445418 18376398 12741479 12898905 18187930 18251166 15057751 17525996 15959796 17823541 18395095 18210741 15931870 15673190 18263696 18705752 15123356 18156304 18420326 18339082 16027843 15996030 12649538
MESH:D008107 Liver Diseases Carbon Tetrachloride 2.1615830285 16964402 15720792 16246199 17285989
MESH:D017093 Liver Failure Carbon Tetrachloride 4.8215123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 4.1416899240 14706259
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 2.3519294768
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 2.8612014681 15583823
MESH:D013733 Testicular Diseases phenethyl isothiocyanate 5.6815864552
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA128394627
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


    Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved