Annotation Detail for VPS39
Basic Information
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| Gene Symbol: | VPS39 ( FLJ21681,FLJ46546,KIAA0770,TLP,VAM6,hVam6p ) |
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| Gene Full Name: | vacuolar protein sorting 39 homolog (S. cerevisiae) |
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| Band: | 15q15.1 |
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| Quick Links | Entrez ID:23339; OMIM: 612188; Uniprot ID:VPS39_HUMAN; ENSEMBL ID: ENSG00000166887; HGNC ID: 20593 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D001104 |
Arbutin |
Arbutin results in increased expression of VPS39 mRNA | increases expression | 17103032
|
| D007657 |
Ketone Bodies |
Ketone Bodies results in increased expression of VPS39 mRNA | increases expression | 16807920
|
| D011794 |
Quercetin |
Quercetin results in increased expression of VPS39 mRNA | increases expression | 17103110
|
| D012643 |
Selenium |
[Selenium co-treated with Vitamin E] results in increased expression of VPS39 mRNA | affects cotreatment|increases expression | 19244175
|
| D012643 |
Selenium |
Selenium results in increased expression of VPS39 mRNA | increases expression | 19244175
|
| D014810 |
Vitamin E |
[Selenium co-treated with Vitamin E] results in increased expression of VPS39 mRNA | affects cotreatment|increases expression | 19244175
|
| D014810 |
Vitamin E |
Vitamin E results in increased expression of VPS39 mRNA | increases expression | 19244175
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000743 |
Anemia, Hemolytic |
|
Quercetin |
4.61 | 17084956 |
| MESH:D001260 |
Ataxia Telangiectasia |
|
Quercetin |
5.52 | 15336622 |
| MESH:D001327 |
Autoimmune Diseases |
|
Quercetin |
4.89 | 19761891 |
| MESH:D001943 |
Breast Neoplasms |
|
Quercetin |
2.62 | 18628248 |
| MESH:D002105 |
Cadmium Poisoning |
|
Quercetin |
6.16 | 16962696 |
| MESH:D002252 |
Carbon Tetrachloride Poisoning |
|
Vitamin E |
4.41 | 16050911 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Quercetin |
2.30 | 19519916 12508355 |
| MESH:D021441 |
Carcinoma, Pancreatic Ductal |
|
Quercetin |
5.44 | 17234771 |
| MESH:D006332 |
Cardiomegaly |
|
Quercetin |
3.49 | 19794523 |
| MESH:D003092 |
Colitis |
|
Selenium |
4.26 | 17936198 |
| MESH:D003110 |
Colonic Neoplasms |
|
Quercetin |
2.46 | 19056647 16640504 19440933 17148506 11134977 15741050 17191121 |
| MESH:D015179 |
Colorectal Neoplasms |
|
Quercetin |
2.19 | 18852136 18095365 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Vitamin E |
1.92 | 19769572 |
| MESH:D003921 |
Diabetes Mellitus, Experimental |
|
Quercetin |
4.04 | 19496084 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Selenium |
2.25 | 15131321 |
| MESH:C538011 |
Eales disease |
|
Vitamin E |
5.32 | 9068938 |
| MESH:D005355 |
Fibrosis |
|
Quercetin |
4.38 | 19474275 |
| MESH:D005909 |
Glioblastoma |
|
Quercetin |
3.61 | 19804834 |
| MESH:D005910 |
Glioma |
|
Quercetin |
3.17 | 17643826 |
| MESH:D006330 |
Heart Defects, Congenital |
|
Vitamin E |
3.15 | 16080930 |
| MESH:D006333 |
Heart Failure |
|
Selenium |
3.27 | 17162251 |
| MESH:D006548 |
Hernia, Diaphragmatic |
|
Vitamin E |
2.80 | 16490937 16863852 |
| MESH:D019584 |
Hot Flashes |
|
Vitamin E |
4.58 | 14716179 |
| MESH:D006943 |
Hyperglycemia |
|
Quercetin |
4.38 | 18262572 11834736 |
| MESH:D006973 |
Hypertension |
|
Quercetin |
2.96 | 18356687 |
| MESH:D007251 |
Influenza, Human |
|
Quercetin |
22.57 | 16624496 |
| MESH:D007251 |
Influenza, Human |
|
Selenium |
22.57 | 16624496 |
| MESH:D007251 |
Influenza, Human |
|
Vitamin E |
22.57 | 16624496 |
| MESH:D007627 |
Keloid |
|
Quercetin |
5.44 | 17086741 |
| MESH:D007674 |
Kidney Diseases |
|
Quercetin |
6.91 | 16962696 |
| MESH:D007674 |
Kidney Diseases |
|
Vitamin E |
6.91 | 12488133 |
| MESH:D007676 |
Kidney Failure, Chronic |
|
Selenium |
4.26 | 16518626 |
| MESH:D007938 |
Leukemia |
|
Quercetin |
3.31 | 17468513 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Quercetin |
2.77 | 12741479 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Vitamin E |
2.77 | 16169303 |
| MESH:D008113 |
Liver Neoplasms |
|
Quercetin |
2.77 | 18980244 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
Quercetin |
3.26 | 19519916 |
| MESH:D008171 |
Lung Diseases |
|
Vitamin E |
3.40 | 16863852 |
| MESH:D008175 |
Lung Neoplasms |
|
Quercetin |
2.74 | 16280456 |
| MESH:D008175 |
Lung Neoplasms |
|
Vitamin E |
2.74 | 11062179 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Selenium |
2.97 | 15318939 |
| MESH:D008654 |
Mesothelioma |
|
Selenium |
2.90 | 15107826 |
| MESH:D009203 |
Myocardial Infarction |
|
Quercetin |
3.11 | 19595682 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
Quercetin |
4.07 | 19207477 |
| MESH:D009369 |
Neoplasms |
|
Quercetin |
2.94 | 15185748 |
| MESH:D020078 |
Neurogenic Inflammation |
|
Quercetin |
4.77 | 17929310 |
| MESH:D015663 |
Osteoporosis, Postmenopausal |
|
Quercetin |
4.62 | 19495926 |
| MESH:D010051 |
Ovarian Neoplasms |
|
Quercetin |
2.82 | 19005980 |
| MESH:D010190 |
Pancreatic Neoplasms |
|
Quercetin |
2.95 | 16965848 |
| MESH:D010954 |
Plasmacytoma |
|
Selenium |
5.50 | 15087411 |
| MESH:D011230 |
Precancerous Conditions |
|
Quercetin |
4.31 | 19056647 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Quercetin |
3.34 | 14715546 17292933 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Vitamin E |
3.34 | 15084515 |
| MESH:D012554 |
Schistosomiasis japonica |
|
Quercetin |
6.16 | 16862918 |
| MESH:D012871 |
Skin Diseases |
|
Vitamin E |
2.51 | 18709164 |
| MESH:D020521 |
Stroke |
|
Vitamin E |
3.81 | 16517955 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
Quercetin |
2.91 | 16720314 |
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