AutismKB 2.0

Annotation Detail for VPS8


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Basic Information Top
Gene Symbol:VPS8 ( FLJ32099,KIAA0804 )
Gene Full Name: vacuolar protein sorting 8 homolog (S. cerevisiae)
Band: 3q27.2
Quick LinksEntrez ID:23355; OMIM: NA; Uniprot ID:VPS8_HUMAN; ENSEMBL ID: ENSG00000156931; HGNC ID: 29122
Relate to Another Database: SFARIGene; denovo-db
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D004958 Estradiol Estradiol affects the expression of VPS8 mRNAaffects expression 14699072
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of VPS8 mRNAaffects expression 17555576
D013629 Tamoxifen Tamoxifen affects the expression of VPS8 mRNAaffects expression 17555576
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 5.4114745880
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.8117505938
MESH:D000230 Adenocarcinoma Estradiol 4.5011473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.5014692618
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 4.1211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.9115885639
MESH:D001943 Breast Neoplasms Estradiol 2.0817018787 16675129 14630087 17289903 17261762 12948864 19861407 18497071
MESH:D001943 Breast Neoplasms Tamoxifen 2.0820065188 17440819 16202921 19189210 19410462 21152245 18351453 18815881 16273361 15565566 17261762 19011961 21138602 20544844 11161223 20859285 16873071 19189212 19115204 19221464 19142967 15668708 17242785 17893378 20005174 19084267 19487384 19200415 19059307 19289846 19288272 18855134 19066611 19244106 18425577 17049068 16818667 19155303 19103187 18984771 18997820 18821012 20390343 18629630 20135344
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 5.2116111702
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 5.1619066611
MESH:D006528 Carcinoma, Hepatocellular Estradiol 3.1416924424
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 3.1416924424
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 4.0617572228
MESH:D002471 Cell Transformation, Neoplastic Estradiol 3.0618566989
MESH:D002779 Cholestasis Ethinyl Estradiol 3.2017681005 11677210 16919318 15861022 16105132 17333356 17110522
MESH:D003711 Demyelinating Diseases Tamoxifen 5.0219031437
MESH:D003928 Diabetic Nephropathies Estradiol 10.2519279558
MESH:D003928 Diabetic Nephropathies Tamoxifen 10.2519279558
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 10.9612538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 10.9619031437
MESH:D016889 Endometrial Neoplasms Estradiol 8.2911473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Tamoxifen 8.2916202921 20544844 19155303 17893378
MESH:D005234 Fatty Liver Ethinyl Estradiol 9.3415345470
MESH:D005234 Fatty Liver Tamoxifen 9.3419224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.4716709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 5.2714745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.9219069698
MESH:D006558 Herpes Genitalis Estradiol 5.9015709030
MESH:D019584 Hot Flashes Estradiol 4.6217088409
MESH:D007021 Hypospadias Ethinyl Estradiol 4.4616569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.9912013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.7617937319
MESH:D007249 Inflammation Tamoxifen 2.5519457130
MESH:D007333 Insulin Resistance Estradiol 3.2316393666 16627594
MESH:D007674 Kidney Diseases Estradiol 2.8015618244
MESH:D007680 Kidney Neoplasms Estradiol 8.7015610895
MESH:D007680 Kidney Neoplasms Tamoxifen 8.7018625569
MESH:D008064 Lipidoses Tamoxifen 3.4615342952 17567588
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 2.5414716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 2.5418564211
MESH:D008113 Liver Neoplasms Tamoxifen 2.3416684651
MESH:D008175 Lung Neoplasms Tamoxifen 1.7518625569
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 4.5019428831
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 6.8617203775 16891317 11408345 11807958
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 6.8614580682 19196722 11731420 19196723 16827153
MESH:D020149 Manganese Poisoning Estradiol 15.7619453300
MESH:D020149 Manganese Poisoning Tamoxifen 15.7619453300
MESH:D008545 Melanoma Tamoxifen 1.9219393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.9215990972
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.6216810080
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.6819393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.6219410462
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.8719196722 19189210 19200415
MESH:D009389 Neovascularization, Pathologic Estradiol 4.4717289903
MESH:D009421 Nervous System Malformations Estradiol 4.2311399458 16427766
MESH:D010051 Ovarian Neoplasms Estradiol 2.3219401270
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.2211578682
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 4.3720887781
MESH:D011471 Prostatic Neoplasms Estradiol 3.0816740699
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.0815067354
MESH:D011537 Pruritus Ethinyl Estradiol 4.0516919318 15861022
MESH:D013088 Spermatocele Ethinyl Estradiol 14.6716709447
MESH:D013088 Spermatocele Tamoxifen 14.6716709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.7819457130
MESH:D019851 Thrombophilia Ethinyl Estradiol 4.1511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.5715669648
MESH:D013978 Tibial Fractures Estradiol 5.5519048282
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 2.498653321 17572228 16712894
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.8814692618
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 4.0215869587 14671159
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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