AutismKB 2.0

Annotation Detail for SIK3


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Basic Information Top
Gene Symbol:SIK3 ( FLJ12240,KIAA0999,QSK )
Gene Full Name: SIK family kinase 3
Band: 11q23.3
Quick LinksEntrez ID:23387; OMIM: NA; Uniprot ID:SIK3_HUMAN; ENSEMBL ID: ENSG00000160584; HGNC ID: 29165
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
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Pathway IDPathway Name
200061LKB1 signaling events
No data
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Related Diseases/Disorders Top
No data
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Desease Name
METABOLIC
triglycerides
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in increased expression of SIK3 mRNAincreases expression 18687144
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055370 Lung Injury Asbestos, Crocidolite 4.9317365036
MESH:D008654 Mesothelioma Asbestos, Crocidolite 3.3416166281 16966607 18303189
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 5.8010923243
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 3.1815814490 17365031 17322281 17975199
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA147031775
    • No data
    Releated disease ID Related disease Name
    PA444528Hyperlipidemias
    PA446120Hypertriglyceridemia
    PA443635Cardiovascular Diseases
    PA443560Breast Neoplasms
    Releated drug ID Related drug Name
    PA449594fenofibrate
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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