AutismKB 2.0

Annotation Detail for KIAA0368


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Basic Information Top
Gene Symbol:KIAA0368 ( ECM29,FLJ22036,KIAA1962 )
Gene Full Name: KIAA0368
Band: 9q31.3
Quick LinksEntrez ID:23392; OMIM: NA; Uniprot ID:; ENSEMBL ID: ENSG00000136813; HGNC ID: 29020
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000638 Amiodarone Amiodarone results in decreased expression of KIAA0368 mRNAdecreases expression 17991464
C006632 arsenic trioxide arsenic trioxide results in increased expression of KIAA0368 mRNAincreases expression 20458559
D016572 Cyclosporine Cyclosporine results in increased expression of KIAA0368 mRNAincreases expression 20106945
D004958 Estradiol Estradiol affects the expression of KIAA0368 mRNAaffects expression 14699072
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma arsenic trioxide 4.6519825857 11798837
MESH:D000230 Adenocarcinoma Estradiol 4.6511473722
MESH:D001145 Arrhythmias, Cardiac Amiodarone 4.2018218290 18057881 20041841
MESH:D001281 Atrial Fibrillation Amiodarone 4.2018651412 19698954
MESH:D001778 Blood Coagulation Disorders Amiodarone 10.7319483382
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 10.7316206674
MESH:D001943 Breast Neoplasms Estradiol 2.1017289903 14630087 12948864 17261762 17018787 16675129 19861407 18497071
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.7911589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 5.0916111702
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 3.1716217749 11135700 14691202 15553829 15073043
MESH:D006528 Carcinoma, Hepatocellular Estradiol 3.1716924424
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.6019014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.5112490120
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 3.0015710769 19225199
MESH:D002341 Carotid Artery Thrombosis Amiodarone 5.7218974383
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 7.4612371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 7.4618566989
MESH:D002779 Cholestasis Cyclosporine 3.2119486331
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D023903 Coronary Restenosis arsenic trioxide 4.6912609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 1.8910525206
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.5615213294
MESH:D003928 Diabetic Nephropathies Estradiol 3.7819279558
MESH:D056486 Drug-Induced Liver Injury Amiodarone 2.4715265979 18218290
MESH:D016889 Endometrial Neoplasms Estradiol 3.2211473722 18566989 19148513
MESH:D004938 Esophageal Neoplasms arsenic trioxide 2.3812903497
MESH:D005234 Fatty Liver Amiodarone 15.7614986274
MESH:D005234 Fatty Liver arsenic trioxide 15.7615073043
MESH:D005234 Fatty Liver Cyclosporine 15.7619224547
MESH:D005355 Fibrosis Cyclosporine 3.7012639820 12168785
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.7716904648
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.858708960
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 5.0515720958
MESH:D006529 Hepatomegaly Amiodarone 4.3115265979
MESH:D006558 Herpes Genitalis Estradiol 5.7615709030
MESH:D019584 Hot Flashes Estradiol 4.4717088409
MESH:D006937 Hypercholesterolemia Amiodarone 4.309751232 8137927
MESH:D006973 Hypertension Cyclosporine 2.2110903974
MESH:D007037 Hypothyroidism Amiodarone 5.0818020914 17991464
MESH:D007333 Insulin Resistance Estradiol 3.2116627594 16393666
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.1615604871
MESH:D007674 Kidney Diseases Cyclosporine 6.6218776723 10903974 8314463
MESH:D007674 Kidney Diseases Estradiol 6.6215618244
MESH:D007680 Kidney Neoplasms Cyclosporine 8.4412371664
MESH:D007680 Kidney Neoplasms Estradiol 8.4415610895
MESH:D007938 Leukemia arsenic trioxide 3.0015070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 4.2212560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.9416972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.7214633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 4.1919077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1916467208 16968895 20471514 19850784 17050201
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.4617712046 16330433 19642359 17217047 15748426 16331271 19035177 15336539 16891316 17869043 15213294 19225113 12712474 12018890 19075265 16966277 9834237 17649720 11468182 11161223 16112521 15622746 17107899 12679006 16823087
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.8616882451
MESH:D008064 Lipidoses Amiodarone 3.7917567588 15342952
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 1.6814716833 14659978
MESH:D008113 Liver Neoplasms arsenic trioxide 2.4614682389
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 2.9620377131
MESH:D008133 Long QT Syndrome Amiodarone 9.2415350150 11989578 17391786
MESH:D008133 Long QT Syndrome arsenic trioxide 9.2415213294
MESH:D008171 Lung Diseases Amiodarone 3.6212587719
MESH:D017563 Lung Diseases, Interstitial Amiodarone 5.2018516814
MESH:D008175 Lung Neoplasms arsenic trioxide 1.8711798837 19825857
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.7916891317 11807958 17203775 11408345
MESH:D020149 Manganese Poisoning Estradiol 5.2119453300
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.5116801185
MESH:D009101 Multiple Myeloma arsenic trioxide 3.3815949261 19417148 19549372 14977855 11468182
MESH:D009181 Mycoses Amiodarone 5.6212754197 17974566
MESH:D009182 Mycosis Fungoides arsenic trioxide 5.4018349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.3416105982 16882451
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.5916810080
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.4716624393
MESH:D009389 Neovascularization, Pathologic Estradiol 4.3617289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.1617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.6518481113 19348381
MESH:D009421 Nervous System Malformations Estradiol 4.1611399458 16427766
MESH:D009436 Neural Tube Defects arsenic trioxide 3.3610525206
MESH:D010051 Ovarian Neoplasms arsenic trioxide 5.1612452020 19769630 16624393
MESH:D010051 Ovarian Neoplasms Estradiol 5.1619401270
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.6315580305
MESH:D010235 Paraganglioma arsenic trioxide 4.6319927285
MESH:D011230 Precancerous Conditions Cyclosporine 3.5912371664
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 4.3120887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.1419131511
MESH:D011471 Prostatic Neoplasms Estradiol 3.1416740699
MESH:D011565 Psoriasis Cyclosporine 2.3316882103
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.9712832656 12490602 11597910
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.4716646077
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 5.7218724381
MESH:D013274 Stomach Neoplasms arsenic trioxide 1.8617007042
MESH:D013276 Stomach Ulcer Amiodarone 3.7418087811
MESH:D013610 Tachycardia Amiodarone 4.8011238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.7019225199
MESH:D013959 Thyroid Diseases Amiodarone 5.4819731979
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.3919014326
MESH:D013971 Thyrotoxicosis Amiodarone 5.4219584973 18020914
MESH:D013978 Tibial Fractures Estradiol 5.4119048282
MESH:D016171 Torsades de Pointes Amiodarone 12.4611989578 17467628
MESH:D016171 Torsades de Pointes arsenic trioxide 12.4615213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 2.6012973940 20435036 11780464 12845720
MESH:D014605 Uveitis Cyclosporine 4.711336536
MESH:D014985 Xerophthalmia Cyclosporine 5.1617120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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