Annotation Detail for KCNH4
Basic Information Top
| Gene Symbol: | KCNH4 ( BEC2,ELK1,Kv12.3 ) |
|---|---|
| Gene Full Name: | potassium voltage-gated channel, subfamily H (eag-related), member 4 |
| Band: | 17q21.2 |
| Quick Links | Entrez ID:23415; OMIM: 604528; Uniprot ID:KCNH4_HUMAN; ENSEMBL ID: ENSG00000089558; HGNC ID: 6253 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of KCNH4 mRNA | affects expression | 16483693 |
| D000431 | Ethanol | Ethanol results in decreased expression of KCNH4 mRNA | decreases expression | 15353170 |
| D018038 | Sodium Selenite | Sodium Selenite results in decreased expression of KCNH4 mRNA | decreases expression | 18175754 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000014 | Abnormalities, Drug-Induced | Ethanol | 4.66 | 17676605 18926900 | |
| MESH:D000138 | Acidosis | Ammonium Chloride | 13.08 | 18287403 | |
| MESH:D000138 | Acidosis | Ethanol | 13.08 | 11192467 | |
| MESH:D020268 | Alcohol-Induced Disorders, Nervous System | Ethanol | 6.19 | 15451040 15451039 | |
| MESH:D000853 | Anophthalmos | Ethanol | 5.47 | 15513904 | |
| MESH:D001008 | Anxiety Disorders | Ethanol | 4.37 | 11141031 | |
| MESH:D002056 | Burns | Ethanol | 5.30 | 16374292 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Ethanol | 2.43 | 15763234 18788625 15289165 | |
| MESH:D006332 | Cardiomegaly | Ethanol | 3.65 | 19332462 | |
| MESH:D019457 | Chromosome Breakage | Sodium Selenite | 5.41 | 15894690 | |
| MESH:D002971 | Cleft Lip | Ethanol | 3.78 | 15513904 | |
| MESH:D002972 | Cleft Palate | Ethanol | 3.32 | 15513904 | |
| MESH:D019465 | Craniofacial Abnormalities | Ethanol | 2.34 | 19302082 15451040 15451039 10194807 15513904 11873399 11198716 | |
| MESH:D003920 | Diabetes Mellitus | Sodium Selenite | 4.19 | 16285004 | |
| MESH:D056486 | Drug-Induced Liver Injury | Ethanol | 4.54 | 11566570 | |
| MESH:D056486 | Drug-Induced Liver Injury | Sodium Selenite | 4.54 | 15131321 | |
| MESH:D004938 | Esophageal Neoplasms | Ethanol | 2.83 | 16704527 | |
| MESH:D005234 | Fatty Liver | Ethanol | 4.21 | 16409862 18620774 19236843 | |
| MESH:D005235 | Fatty Liver, Alcoholic | Ethanol | 6.53 | 17920746 | |
| MESH:D005310 | Fetal Alcohol Syndrome | Ethanol | 6.04 | 16946407 10194807 15451040 15513904 | |
| MESH:D005756 | Gastritis | Ethanol | 5.56 | 15046732 | |
| MESH:D006930 | Hyperalgesia | Ethanol | 4.08 | 18783367 | |
| MESH:D007333 | Insulin Resistance | Sodium Selenite | 3.54 | 14714311 | |
| MESH:D007569 | Jaw Abnormalities | Ethanol | 4.89 | 15513904 | |
| MESH:D007859 | Learning Disorders | Ethanol | 4.86 | 15451040 | |
| MESH:D017880 | Limb Deformities, Congenital | Ethanol | 4.12 | 17676605 | |
| MESH:D008103 | Liver Cirrhosis | Ethanol | 3.58 | 15289165 | |
| MESH:D008104 | Liver Cirrhosis, Alcoholic | Ethanol | 5.84 | 18295389 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Ethanol | 2.32 | 18166357 | |
| MESH:D008108 | Liver Diseases, Alcoholic | Ethanol | 5.30 | 17347304 17207112 | |
| MESH:D016393 | Lymphoma, B-Cell | Sodium Selenite | 4.59 | 14737004 | |
| MESH:D008569 | Memory Disorders | Ethanol | 4.77 | 18411066 15451040 | |
| MESH:D010190 | Pancreatic Neoplasms | Ethanol | 3.09 | 12384795 | |
| MESH:D011471 | Prostatic Neoplasms | Sodium Selenite | 3.33 | 18760546 | |
| MESH:D012640 | Seizures | Ethanol | 3.45 | 9754883 | |
| MESH:D013274 | Stomach Neoplasms | Ethanol | 2.31 | 18456281 | |
| MESH:D013276 | Stomach Ulcer | Ethanol | 4.01 | 9211565 16755016 9562338 17918041 17189318 11906479 | |
| MESH:D013375 | Substance Withdrawal Syndrome | Ethanol | 4.70 | 9754883 |
| No data |