AutismKB 2.0

Annotation Detail for GRIP1


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Basic Information Top
Gene Symbol:GRIP1 ( GRIP )
Gene Full Name: glutamate receptor interacting protein 1
Band: 12q14.3
Quick LinksEntrez ID:23426; OMIM: 604597; Uniprot ID:GRIP1_HUMAN; ENSEMBL ID: ENSG00000155974; HGNC ID: 18708
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C014949 acetylhydrazine acetylhydrazine results in decreased expression of GRIP1 mRNAdecreases expression 15282401
D017638 Asbestos, Crocidolite Asbestos, Crocidolite affects the expression of GRIP1 mRNAaffects expression 17331233
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of GRIP1 mRNAaffects binding|increases activity|increases expression 19710929
C025643 vinclozolin vinclozolin affects the expression of GRIP1 mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055371 Acute Lung Injury pirinixic acid 3.5818653653
MESH:D018248 Adenoma, Liver Cell pirinixic acid 4.1116434500
MESH:D001008 Anxiety Disorders vinclozolin 3.9719015723
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.5719483382
MESH:D002779 Cholestasis pirinixic acid 3.1219176532
MESH:D003456 Cryptorchidism vinclozolin 4.8514966744
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5718249437
MESH:D004487 Edema pirinixic acid 2.9012083418
MESH:D005234 Fatty Liver pirinixic acid 3.1919236843 20131406
MESH:D030342 Genetic Diseases, Inborn vinclozolin 5.5716973722
MESH:D005832 Genital Diseases, Male vinclozolin 6.0216417039
MESH:D006333 Heart Failure pirinixic acid 2.7620558911
MESH:D006529 Hepatomegaly pirinixic acid 3.5516221962 19176532 18467677 19772884
MESH:D006943 Hyperglycemia pirinixic acid 3.5820558911
MESH:D007248 Infertility, Male vinclozolin 3.2916467254
MESH:D007333 Insulin Resistance pirinixic acid 2.8716306350
MESH:D007984 Leydig Cell Tumor vinclozolin 5.3616417039
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008113 Liver Neoplasms pirinixic acid 1.9320007298 16377806 15890375
MESH:D055370 Lung Injury Asbestos, Crocidolite 4.5817365036
MESH:D008654 Mesothelioma Asbestos, Crocidolite 3.3118303189 16966607 16166281
MESH:D009135 Muscular Diseases pirinixic acid 4.0716239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.2719151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.2516411023
MESH:D009369 Neoplasms pirinixic acid 2.1117405874
MESH:D009765 Obesity pirinixic acid 1.8820558911
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 5.4510923243
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 4.5318220299 19015723 18042343
MESH:D011469 Prostatic Diseases vinclozolin 5.5718220299
MESH:D011472 Prostatitis vinclozolin 5.5718629315
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 3.1517322281 15814490 17975199 17365031
MESH:D015427 Reperfusion Injury pirinixic acid 2.5519058328
Pathway ID Pathway Name
REACT:13685 Synaptic Transmission
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA38652
    • No data
    No data
    Releated drug ID Related drug Name
    PA164768822chlorotrianisene
    PA164754789conjugated estrogens
    PA164745534dienestrol
    PA449307diethylstilbestrol
    PA449503estradiol
    PA449509estrogens
    PA449512estrone
    PA449527ethinyl estradiol
    Drug Bank Top

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      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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