AutismKB 2.0

Annotation Detail for ABCB9


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Basic Information Top
Gene Symbol:ABCB9 ( EST122234,KIAA1520,TAPL,hABCB9 )
Gene Full Name: ATP-binding cassette, sub-family B (MDR/TAP), member 9
Band: 12q24.31
Quick LinksEntrez ID:23457; OMIM: 605453; Uniprot ID:ABCB9_HUMAN; ENSEMBL ID: ENSG00000150967; HGNC ID: 50
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of ABCB9 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of ABCB9 mRNAaffects expression 16483693
D005419 Flavonoids Flavonoids results in decreased expression of ABCB9 mRNAdecreases expression 18035473
D015725 Fluconazole Fluconazole results in decreased expression of ABCB9 mRNAdecreases expression 16643972
D020849 Raloxifene Raloxifene affects the expression of ABCB9 mRNAaffects expression 14699072
C446685 systhane systhane results in increased expression of ABCB9 mRNAincreases expression 16643972
C032910 triadimefon triadimefon results in increased expression of ABCB9 mRNAincreases expression 16643972
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 3.9518287403
MESH:D000419 Albuminuria Raloxifene 4.9217451421 17308373
MESH:D000544 Alzheimer Disease Raloxifene 2.5915800139
MESH:D000799 Angioedema Acetaminophen 4.2910982225
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001930 Brain Injuries Raloxifene 4.8316580743
MESH:D001943 Breast Neoplasms Raloxifene 2.6415572757 17893378 15758505 15775269 17242785 17261762 17595753 17440819 16912660 17049068 17952589 16837676
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.403084413
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 4.3417572228
MESH:D002318 Cardiovascular Diseases Raloxifene 3.6315775269
MESH:D002386 Cataract Acetaminophen 2.7310977129
MESH:D002972 Cleft Palate Fluconazole 7.3316781842
MESH:D002972 Cleft Palate triadimefon 7.3316781842
MESH:D003072 Cognition Disorders Raloxifene 4.9815800139
MESH:D019465 Craniofacial Abnormalities triadimefon 2.8916875885 15834900
MESH:D003865 Depressive Disorder, Major Raloxifene 4.4117474826
MESH:D003928 Diabetic Nephropathies Raloxifene 4.1817308373 17451421 15920148
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6514550746 15968718 11739529 11287661 12540782 10915739 17906064 19739265 12705907 17522070 11461765 16109766 18071297 16081117 14725611 19420014 11743745 12594235 19416960 12958197 16781746 2444490 11529661 19923254 16393943 19164858 12392966 15619225 16485898 14986274 17562736 19085960 19370779 11421492 10663392 16177239 18713872 11834606 10774834 16227642 12153990
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.5419426721
MESH:D004487 Edema Raloxifene 3.6115860553
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 4.3215845917
MESH:D005234 Fatty Liver Raloxifene 3.9017473493
MESH:D005756 Gastritis Acetaminophen 4.1216983495
MESH:D006331 Heart Diseases Raloxifene 3.7211110106
MESH:D006529 Hepatomegaly systhane 10.7317178689 17178688
MESH:D006529 Hepatomegaly triadimefon 10.7317178689 17178688
MESH:D006930 Hyperalgesia Acetaminophen 2.9216870215
MESH:D006973 Hypertension Raloxifene 2.9517577099 15787275
MESH:D007249 Inflammation Flavonoids 2.7717296493
MESH:D007569 Jaw Abnormalities triadimefon 5.2415834900 15992940
MESH:D007674 Kidney Diseases Acetaminophen 2.3412587719 15629191
MESH:D007889 Leiomyoma Raloxifene 4.8016973256
MESH:D008107 Liver Diseases Acetaminophen 7.2219014921 16611625 19460945 12969438 19784758 12587719 16610002 11587558
MESH:D008107 Liver Diseases Fluconazole 7.2214966256
MESH:D008107 Liver Diseases triadimefon 7.2219363144
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5016871587 17185352
MESH:D008113 Liver Neoplasms triadimefon 3.4219028983
MESH:D008114 Liver Neoplasms, Experimental systhane 7.4017178689
MESH:D008114 Liver Neoplasms, Experimental triadimefon 7.4017178689
MESH:D008171 Lung Diseases Fluconazole 5.0014966256
MESH:D008546 Melanoma, Experimental Acetaminophen 3.9319513568
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 6.0015863610
MESH:D009101 Multiple Myeloma Raloxifene 3.6316497877
MESH:D009232 Myxoma Raloxifene 6.0016343187
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1018514411
MESH:D014009 Onychomycosis Fluconazole 6.7914966256
MESH:D010024 Osteoporosis Raloxifene 3.5517882678 15775268 19059307
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 4.5315758505 17823083 15579764 17893378
MESH:D010146 Pain Acetaminophen 2.6216870215
MESH:D011471 Prostatic Neoplasms Raloxifene 3.5616220300 16536755 15731164
MESH:D011693 Purpura Raloxifene 6.0015770314
MESH:D020521 Stroke Raloxifene 4.0416837676
MESH:D013964 Thyroid Neoplasms triadimefon 4.2917178689
MESH:D013978 Tibial Fractures Raloxifene 5.6519048282
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 2.9017572228
MESH:D014581 Urticaria Acetaminophen 3.2810982225
MESH:D054556 Venous Thromboembolism Raloxifene 5.6516837676
MESH:D014846 Vulvar Neoplasms Raloxifene 6.0016343187
Pathway ID Pathway Name
KEGG:02010 ABC transporters
KEGG:04142 Lysosome
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA24391
  • Releated gene ID Related gene Name
    PA24391ABCB9
    No data
    No data
    Drug Bank Top

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      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018