Annotation Detail for NPTXR
Basic Information
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| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D000638 |
Amiodarone |
Amiodarone results in increased expression of NPTXR mRNA | increases expression | 19774075
|
| D002713 |
Chlorine |
[Ozone co-treated with Chlorine] results in increased expression of NPTXR mRNA | affects cotreatment|increases expression | 18636392
|
| D000431 |
Ethanol |
Ethanol results in increased expression of NPTXR mRNA | increases expression | 17920746
|
| D010126 |
Ozone |
[Ozone co-treated with Chlorine] results in increased expression of NPTXR mRNA | affects cotreatment|increases expression | 18636392
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
Ethanol |
4.55 | 18926900 17676605 |
| MESH:D000138 |
Acidosis |
|
Ethanol |
5.13 | 11192467 |
| MESH:D055371 |
Acute Lung Injury |
|
Chlorine |
4.78 | 20601635 |
| MESH:D020268 |
Alcohol-Induced Disorders, Nervous System |
|
Ethanol |
6.04 | 15451040 15451039 |
| MESH:D000544 |
Alzheimer Disease |
|
Ozone |
2.50 | 15513908 |
| MESH:D000853 |
Anophthalmos |
|
Ethanol |
5.38 | 15513904 |
| MESH:D001008 |
Anxiety Disorders |
|
Ethanol |
4.33 | 11141031 |
| MESH:D001145 |
Arrhythmias, Cardiac |
|
Amiodarone |
4.20 | 18218290 18057881 20041841 |
| MESH:D001172 |
Arthritis, Rheumatoid |
|
Ozone |
2.63 | 15570426 |
| MESH:D001249 |
Asthma |
|
Ozone |
2.73 | 17854713 16373670 |
| MESH:D001281 |
Atrial Fibrillation |
|
Amiodarone |
4.20 | 19698954 18651412 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
Amiodarone |
4.32 | 19483382 |
| MESH:D016535 |
Bronchial Hyperreactivity |
|
Ozone |
4.00 | 14754758 18417511 16777450 18315731 15516495 19059883 17626835 |
| MESH:D002056 |
Burns |
|
Ethanol |
5.21 | 16374292 |
| MESH:D002100 |
Cachexia |
|
Ozone |
5.37 | 16183385 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Ethanol |
2.42 | 15763234 18788625 15289165 |
| MESH:D006332 |
Cardiomegaly |
|
Ethanol |
3.63 | 19332462 |
| MESH:D002311 |
Cardiomyopathy, Dilated |
|
Amiodarone |
3.00 | 19225199 15710769 |
| MESH:D002341 |
Carotid Artery Thrombosis |
|
Amiodarone |
5.72 | 18974383 |
| MESH:D002971 |
Cleft Lip |
|
Ethanol |
3.76 | 15513904 |
| MESH:D002972 |
Cleft Palate |
|
Ethanol |
3.31 | 15513904 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Ethanol |
2.34 | 15451039 11198716 15513904 10194807 15451040 19302082 11873399 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Amiodarone |
4.55 | 15265979 18218290 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Ethanol |
4.55 | 11566570 |
| MESH:D004417 |
Dyspnea |
|
Chlorine |
5.35 | 20016425 |
| MESH:D004938 |
Esophageal Neoplasms |
|
Ethanol |
2.83 | 16704527 |
| MESH:D005234 |
Fatty Liver |
|
Amiodarone |
9.61 | 14986274 |
| MESH:D005234 |
Fatty Liver |
|
Ethanol |
9.61 | 19236843 16409862 18620774 |
| MESH:D005235 |
Fatty Liver, Alcoholic |
|
Ethanol |
6.39 | 17920746 |
| MESH:D005310 |
Fetal Alcohol Syndrome |
|
Ethanol |
5.93 | 15513904 16946407 15451040 10194807 |
| MESH:D005739 |
Gas Poisoning |
|
Chlorine |
5.73 | 20016425 |
| MESH:D005756 |
Gastritis |
|
Ethanol |
5.42 | 15046732 |
| MESH:D006529 |
Hepatomegaly |
|
Amiodarone |
4.31 | 15265979 |
| MESH:D006930 |
Hyperalgesia |
|
Ethanol |
4.04 | 18783367 |
| MESH:D006937 |
Hypercholesterolemia |
|
Amiodarone |
4.30 | 8137927 9751232 |
| MESH:D007037 |
Hypothyroidism |
|
Amiodarone |
5.08 | 18020914 17991464 |
| MESH:D007569 |
Jaw Abnormalities |
|
Ethanol |
4.83 | 15513904 |
| MESH:D007859 |
Learning Disorders |
|
Ethanol |
4.77 | 15451040 |
| MESH:D017880 |
Limb Deformities, Congenital |
|
Ethanol |
4.09 | 17676605 |
| MESH:D008064 |
Lipidoses |
|
Amiodarone |
3.79 | 15342952 17567588 |
| MESH:D008103 |
Liver Cirrhosis |
|
Ethanol |
3.56 | 15289165 |
| MESH:D008104 |
Liver Cirrhosis, Alcoholic |
|
Ethanol |
5.73 | 18295389 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Ethanol |
2.32 | 18166357 |
| MESH:D008108 |
Liver Diseases, Alcoholic |
|
Ethanol |
5.21 | 17207112 17347304 |
| MESH:D008133 |
Long QT Syndrome |
|
Amiodarone |
3.89 | 11989578 15350150 17391786 |
| MESH:D008171 |
Lung Diseases |
|
Amiodarone |
8.44 | 12587719 |
| MESH:D008171 |
Lung Diseases |
|
Ozone |
8.44 | 8266340 19066396 |
| MESH:D017563 |
Lung Diseases, Interstitial |
|
Amiodarone |
5.20 | 18516814 |
| MESH:D055370 |
Lung Injury |
|
Ozone |
4.41 | 20417186 |
| MESH:D008175 |
Lung Neoplasms |
|
Ozone |
2.10 | 7614698 8597069 |
| MESH:D008569 |
Memory Disorders |
|
Ethanol |
4.69 | 18411066 15451040 |
| MESH:D008679 |
Metaplasia |
|
Ozone |
5.83 | 10496685 |
| MESH:D009181 |
Mycoses |
|
Amiodarone |
5.62 | 17974566 12754197 |
| MESH:D010190 |
Pancreatic Neoplasms |
|
Ethanol |
3.08 | 12384795 |
| MESH:D010538 |
Peritonitis |
|
Ozone |
4.69 | 16369182 |
| MESH:D011014 |
Pneumonia |
|
Ozone |
5.03 | 18007984 18929643 18381685 |
| MESH:D011658 |
Pulmonary Fibrosis |
|
Amiodarone |
2.97 | 12832656 11597910 12490602 |
| MESH:D012120 |
Respiration Disorders |
|
Chlorine |
5.93 | 18579056 |
| MESH:D012640 |
Seizures |
|
Ethanol |
3.42 | 9754883 |
| OMIM:609620 |
SHORT QT SYNDROME 1 |
|
Amiodarone |
5.72 | 18724381 |
| MESH:D013274 |
Stomach Neoplasms |
|
Ethanol |
2.31 | 18456281 |
| MESH:D013276 |
Stomach Ulcer |
|
Amiodarone |
8.93 | 18087811 |
| MESH:D013276 |
Stomach Ulcer |
|
Ethanol |
8.93 | 11906479 17918041 17189318 9211565 9562338 16755016 |
| MESH:D013375 |
Substance Withdrawal Syndrome |
|
Ethanol |
4.65 | 9754883 |
| MESH:D013610 |
Tachycardia |
|
Amiodarone |
4.80 | 11238279 |
| MESH:D017180 |
Tachycardia, Ventricular |
|
Amiodarone |
4.70 | 19225199 |
| MESH:D013959 |
Thyroid Diseases |
|
Amiodarone |
5.48 | 19731979 |
| MESH:D013971 |
Thyrotoxicosis |
|
Amiodarone |
5.42 | 18020914 19584973 |
| MESH:D016171 |
Torsades de Pointes |
|
Amiodarone |
4.82 | 11989578 17467628 |
Related Pathway Information