AutismKB 2.0

Annotation Detail for MMD


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Basic Information Top
Gene Symbol:MMD ( MMA,PAQR11 )
Gene Full Name: monocyte to macrophage differentiation-associated
Band: 17q22
Quick LinksEntrez ID:23531; OMIM: 604467; Uniprot ID:PAQRB_HUMAN; ENSEMBL ID: ENSG00000108960; HGNC ID: 7153
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of MMD mRNAaffects expression 17562736
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of MMD proteinaffects expression 20106945
C006632 arsenic trioxide arsenic trioxide results in increased expression of MMD mRNAincreases expression 20458559
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MMD mRNAaffects cotreatment|increases expression 18164116
D016572 Cyclosporine Cyclosporine results in increased expression of MMD mRNAincreases expression 20106945
D004041 Dietary Fats Dietary Fats results in decreased expression of MMD mRNAdecreases expression 18042831
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MMD mRNAaffects cotreatment|increases expression 18164116
D002117 Calcitriol Calcitriol results in increased expression of MMD mRNAincreases expression 16002434
D004610 Ellagic Acid Ellagic Acid results in increased expression of MMD mRNAincreases expression 12002526
C044101 endotoxin, Escherichia coli endotoxin, Escherichia coli results in increased expression of MMD mRNAincreases expression 15919760
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MMD mRNAaffects cotreatment|increases expression 17942748
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of MMD mRNAincreases expression 15919760
D015735 Mifepristone Mifepristone results in increased expression of MMD mRNAincreases expression 17584828
C041786 palm oil palm oil results in decreased expression of MMD mRNAdecreases expression 18042831
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of MMD mRNA]affects reaction|decreases expression 19482888
D010634 Phenobarbital Phenobarbital results in decreased expression of MMD mRNAdecreases expression 19482888
C006253 pirinixic acid pirinixic acid results in increased expression of MMD mRNAincreases expression 18301758
C059514 resveratrol resveratrol results in increased expression of MMD mRNAincreases expression 12002526
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MMD mRNAaffects cotreatment|increases expression 17942748
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 8.186195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.1815322242 11752688 14514962
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.9117505938
MESH:D058186 Acute Kidney Injury resveratrol 3.8116538975
MESH:D055371 Acute Lung Injury Lipopolysaccharides 8.9018653653 11850527
MESH:D055371 Acute Lung Injury pirinixic acid 8.9018653653
MESH:D000230 Adenocarcinoma arsenic trioxide 4.2511798837 19825857
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.2514692618
MESH:D000236 Adenoma beta-Naphthoflavone 11.1519389873
MESH:D000236 Adenoma Diethylnitrosamine 11.156695378 10737359
MESH:D000236 Adenoma resveratrol 11.1515688382
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 24.5919061943 17162532 17620307 18056438 19052882 16434500
MESH:D018248 Adenoma, Liver Cell Phenobarbital 24.5917620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 24.5916434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 24.5916835633
MESH:D000544 Alzheimer Disease resveratrol 2.5616162502 16183991
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9111748828
MESH:D000799 Angioedema Acetaminophen 3.8110982225
MESH:D001161 Arteriosclerosis Dietary Fats 9.7815238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.7811256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.2715885639
MESH:D001169 Arthritis, Experimental resveratrol 7.2717115116
MESH:D050197 Atherosclerosis resveratrol 3.2516873680 17967414
MESH:D001321 Autistic Disorder Acetaminophen 1.4218445737
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 15.0516206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 15.0519483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 15.0512125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7315746008
MESH:D002545 Brain Ischemia resveratrol 4.2517600658
MESH:D001943 Breast Neoplasms Calcitriol 2.3311237771
MESH:D001943 Breast Neoplasms Dietary Fats 2.3320435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.3317474063
MESH:D001943 Breast Neoplasms resveratrol 2.3317651959 16393696 17534123
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.3320435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.2911589617
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7616835633
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 11.313084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 11.3112907637 21507988 12619106
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 11.3114691202 15553829 16217749 15073043 11135700
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 11.3120727157 21159647 18210153 16540662 16328049 18494052 20524982 18785209 18393292 3581430 19539802 20084675 18506893 16807293 19701751 18691550 10672840 16830150 17761372 18056438 20214788 19822196 17055752 16698587 16935385 18665156 17173139 19418558 16288022 18971187 19208518 20432363 17978847 16878318 19171122 20101231 3084413 17428255 16569478 16681979 17138121 20935162 19919837 17162532 19052882 19335982 16502159 16779866 10737359 20514400 19519916 19394651 18788625 19383236 19107877 18978308 11831363 20512989 20007298
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 11.3117173139 6705139 20007298 20935162 1701930
MESH:D006528 Carcinoma, Hepatocellular resveratrol 11.3116227395 19321006
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.5616675471
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.8519014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.0812490120
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 4.8911237771
MESH:D002294 Carcinoma, Squamous Cell resveratrol 4.8916227395
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3416120746 18670907 18850075
MESH:D002318 Cardiovascular Diseases resveratrol 3.4415458977
MESH:D002386 Cataract Acetaminophen 2.5510977129
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 6.5012371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 6.5017174075 21159647 2727394 7505956
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.214080065
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 9.2019052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 9.2016835633
MESH:D002779 Cholestasis Cyclosporine 13.1519486331
MESH:D002779 Cholestasis Ethinyl Estradiol 13.1517681005 15861022 16105132 11677210 16919318 17333356 17110522
MESH:D002779 Cholestasis pirinixic acid 13.1519176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0816354765 15340226 12621046 8697196 15668235
MESH:D003092 Colitis resveratrol 4.0916474422
MESH:D003110 Colonic Neoplasms resveratrol 2.4516338953
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.6220501625
MESH:D015179 Colorectal Neoplasms resveratrol 2.6216550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0217141729 14669216
MESH:D003327 Coronary Disease resveratrol 3.7216507316
MESH:D023903 Coronary Restenosis arsenic trioxide 4.1412609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.4610525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4620055451 10048152 15322242
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.0515213294
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4018249437
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.7316873680
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.1820387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.1817107852
MESH:D003928 Diabetic Nephropathies resveratrol 3.9216286809
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.0510663392 11287661 10774834 14986274 19370779 11461765 17562736 10915739 19420014 16781746 16393943 15968718 16485898 19416960 18713872 16177239 11529661 14725611 12594235 16109766 12392966 11834606 19164858 17906064 12958197 18071297 17522070 19085960 11421492 16227642 2444490 12705907 15619225 11743745 12153990 19739265 19923254 16081117 12540782 11739529 14550746
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 6.0519107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 6.0520420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.0719426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7311462148
MESH:D050171 Dyslipidemias Dietary Fats 3.4218367378
MESH:D004421 Dystonia Phenobarbital 3.961851702
MESH:D004487 Edema pirinixic acid 11.2012083418
MESH:D004487 Edema resveratrol 11.208985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 11.2012711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.8715322242 18230668 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 15.1815138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 15.1812538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 15.1817872969
MESH:D004715 Endometriosis Mifepristone 9.0216134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 9.0210568697 9294722
MESH:D019446 Endotoxemia endotoxin, Escherichia coli 10.9318509659 17637181
MESH:D019446 Endotoxemia Lipopolysaccharides 10.9315821434 15328337 17637181
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.8117923197
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.073659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.843922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.8720417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.506401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.217750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.983659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.0916302075
MESH:D004938 Esophageal Neoplasms arsenic trioxide 2.3012903497
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9811564622
MESH:D005234 Fatty Liver arsenic trioxide 30.2215073043
MESH:D005234 Fatty Liver Cyclosporine 30.2219224547
MESH:D005234 Fatty Liver Dietary Fats 30.2219551842 18296743 17967931 19004024
MESH:D005234 Fatty Liver Diethylnitrosamine 30.2221071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 30.2215345470
MESH:D005234 Fatty Liver pirinixic acid 30.2220131406 19236843
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.4211858732
MESH:D005334 Fever endotoxin, Escherichia coli 9.6216997862
MESH:D005334 Fever Lipopolysaccharides 9.629205823 11852909
MESH:D005355 Fibrosis Cyclosporine 14.5012168785 12639820
MESH:D005355 Fibrosis Dietary Fats 14.5018296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 14.5020067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.2216904648
MESH:D005756 Gastritis Acetaminophen 3.6516983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.188708960
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5710696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.3110048152 11294989
MESH:D006333 Heart Failure pirinixic acid 2.5120558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.3915720958
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 4.3416366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2911000095
MESH:D006529 Hepatomegaly Phenobarbital 14.1616109766
MESH:D006529 Hepatomegaly pirinixic acid 14.1618467677 16221962 19176532 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 14.1615340226 12621046 16120746
MESH:D006561 Herpes Simplex resveratrol 4.1416876885
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.0216959395 15340226 16354765 8697196 18606429
MESH:D006930 Hyperalgesia Acetaminophen 2.6616870215
MESH:D006937 Hypercholesterolemia Dietary Fats 9.0821332399
MESH:D006937 Hypercholesterolemia resveratrol 9.0817188708
MESH:D006943 Hyperglycemia pirinixic acid 3.1420558911
MESH:D006949 Hyperlipidemias Dietary Fats 9.1521332399
MESH:D006949 Hyperlipidemias resveratrol 9.1516873680
MESH:D006973 Hypertension Cyclosporine 4.8910903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.8918670907 18850075
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.2617488730
MESH:D007021 Hypospadias Ethinyl Estradiol 3.7716945680 16569931
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.6117600658
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.4617937319
MESH:D007249 Inflammation Dietary Fats 15.6420412841
MESH:D007249 Inflammation Diethylnitrosamine 15.6418785209
MESH:D007249 Inflammation Lipopolysaccharides 15.6417237260 17255318 12878042 9205823 17963957
MESH:D007249 Inflammation resveratrol 15.6416366677
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 15.6412200463 12878042
MESH:D007251 Influenza, Human resveratrol 4.5216624496
MESH:D007333 Insulin Resistance Dietary Fats 7.1518457598 11836018
MESH:D007333 Insulin Resistance pirinixic acid 7.1516306350
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.5917255318
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2916580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.4115604871
MESH:D007674 Kidney Diseases Acetaminophen 5.7112587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 5.7110903974 8314463 18776723
MESH:D007680 Kidney Neoplasms Cyclosporine 2.7012371664
MESH:D007938 Leukemia arsenic trioxide 2.8115070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.7512560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.2716972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.3914633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.7219077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1316467208 17050201 19850784 20471514 16968895
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 7.6917712046 17217047 19035177 17107899 12679006 15336539 9834237 16330433 17869043 11468182 19642359 15622746 17649720 12018890 15213294 15748426 12712474 16331271 16823087 19225113 19075265 16966277 16112521 11161223 16891316
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 7.6916087638
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.3116882451
MESH:D007970 Leukopenia Lipopolysaccharides 4.6615821434
MESH:D008103 Liver Cirrhosis Dietary Fats 10.8918296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 10.8920032147 18407596 18522880 19638242 18665156
MESH:D008103 Liver Cirrhosis Phenobarbital 10.8921047994
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 3.4312878042
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 3.4315474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.4312878042
MESH:D008107 Liver Diseases Acetaminophen 6.4219784758 11587558 19460945 16610002 12969438 12587719 19014921 16611625
MESH:D008107 Liver Diseases Diethylnitrosamine 6.4217034775
MESH:D008107 Liver Diseases Phenobarbital 6.4219363144
MESH:D017114 Liver Failure, Acute Acetaminophen 3.2016871587 17185352
MESH:D008113 Liver Neoplasms Aflatoxin B1 25.7218177683 9163691 15890375 2125692
MESH:D008113 Liver Neoplasms arsenic trioxide 25.7214682389
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 25.7219389873 21295105
MESH:D008113 Liver Neoplasms Diethylnitrosamine 25.7218648771 2422723 19690152 21167192 20452335 19833225 12771043 20501860 19812893 21071580 15175105 19255062 19426721 16942905 19499222 21047994 19254457 18978307 18644402 20583210 21278145 19642983 19638242 19256749 12112319 20492335 18754104 19996281 18977376 20434301 19427195 19551842 20137499 15885732 20101389 9163691 19294768 19850985 20118626 20405173 19090486 19073162 2862719 10737359
MESH:D008113 Liver Neoplasms Phenobarbital 25.7221047994 15975961 19812893 19073162 19482888 8742319
MESH:D008113 Liver Neoplasms pirinixic acid 25.7220007298 16377806 15890375
MESH:D008113 Liver Neoplasms resveratrol 25.7219073162 20405173 19812893 19321006
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 25.7216984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 23.038603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 23.0320377131
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 23.0318164116
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 23.039362446 18164116 16842330 18079962 17854601 18544905 21159647 19126423 18282651 18253720 19004024 18775883 3124819 2563599 16267830 19519916 17174075 17942915 18308698 19009564 18093689 19539802
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 23.032563599 1399818 18308698 17172636 6150874
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 23.0312151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.3115213294
MESH:D055370 Lung Injury Lipopolysaccharides 3.9721114838
MESH:D008175 Lung Neoplasms Aflatoxin B1 4.8014755239
MESH:D008175 Lung Neoplasms arsenic trioxide 4.8011798837 19825857
MESH:D008175 Lung Neoplasms Diethylnitrosamine 4.806695378 20970405 21163286 20512841
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.8019555203 11884234
MESH:D016393 Lymphoma, B-Cell resveratrol 4.2617088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.8314749477
MESH:D015674 Mammary Neoplasms, Animal resveratrol 4.2115688416
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 3.0811606380 8985016
MESH:D008545 Melanoma resveratrol 2.3617992120
MESH:D008546 Melanoma, Experimental Acetaminophen 3.5319513568
MESH:D008659 Metabolic Diseases resveratrol 4.3417112576
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.7616801185
MESH:D009101 Multiple Myeloma arsenic trioxide 7.3119549372 19417148 11468182 14977855 15949261
MESH:D009101 Multiple Myeloma resveratrol 7.3117049120 17164350 16490592 14749477 17935668 16267019
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.8317962980
MESH:D009135 Muscular Diseases pirinixic acid 3.4716239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.6418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.1216882451 16105982
MESH:D009203 Myocardial Infarction pirinixic acid 5.6819151258
MESH:D009203 Myocardial Infarction resveratrol 5.6816456233 17125593 16525036 16317513 17015251 17188708
MESH:D017202 Myocardial Ischemia resveratrol 8.8917125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 8.8912213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.9116411023
MESH:D009205 Myocarditis resveratrol 4.7217322642
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.4417484760
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.9216624393
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.553581430 9029167
MESH:D009369 Neoplasms pirinixic acid 1.9317405874
MESH:D009374 Neoplasms, Experimental resveratrol 3.968985016
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.4117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.2418481113 19348381
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.1714600291
MESH:D009436 Neural Tube Defects arsenic trioxide 3.0910525206
MESH:D019636 Neurodegenerative Diseases Acetaminophen 13.8418514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 13.8420387270
MESH:D019636 Neurodegenerative Diseases resveratrol 13.8417652729
MESH:D020078 Neurogenic Inflammation resveratrol 4.3617929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.0920387270
MESH:D009765 Obesity Dietary Fats 4.4020518802 17217161 20132043 21332399 18674790 19632207 18457598 16723640 11836018
MESH:D009765 Obesity pirinixic acid 4.4020558911
MESH:D010018 Osteomalacia Phenobarbital 4.3317016548
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 4.2117513867
MESH:D010051 Ovarian Neoplasms arsenic trioxide 5.1216624393 19769630 12452020
MESH:D010051 Ovarian Neoplasms Mifepristone 5.1216525653
MESH:D010146 Pain Acetaminophen 2.3516870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 8.5315580305
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 8.5316540662
MESH:D010190 Pancreatic Neoplasms Phenobarbital 8.5316965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6511578682
MESH:D010235 Paraganglioma arsenic trioxide 4.1219927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.2212520081
MESH:D011014 Pneumonia Lipopolysaccharides 4.5211605937 12224865
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5218163543
MESH:D011230 Precancerous Conditions Cyclosporine 15.0512371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 15.052563599
MESH:D011230 Precancerous Conditions Phenobarbital 15.052563599
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 9.4716679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 9.4711222880 11118676 11399792 11896295
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.7415572423
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.6919131511
MESH:D011471 Prostatic Neoplasms Calcitriol 2.6916644109 18247401 12479363 16289102 15754350
MESH:D011471 Prostatic Neoplasms resveratrol 2.6917804756 15767336 17636462 17718901 17675339 16731767
MESH:D011537 Pruritus Ethinyl Estradiol 3.2816919318 15861022
MESH:D019310 Pseudolymphoma Phenobarbital 4.4712752131
MESH:D011565 Psoriasis Cyclosporine 2.2116882103
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.5516325855
MESH:D015427 Reperfusion Injury pirinixic acid 6.5019058328
MESH:D015427 Reperfusion Injury resveratrol 6.5016314181 17520802 17058453 16317513 15827377
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.7010835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8018990726
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.9216646077
MESH:D012640 Seizures Phenobarbital 2.6616876388 3137016 11442880 4039156
MESH:D003294 Seizures, Febrile Phenobarbital 4.796407741
MESH:D012772 Shock, Septic endotoxin, Escherichia coli 5.6018063050
MESH:D012878 Skin Neoplasms resveratrol 5.6515837718 8985016
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.6516192470
MESH:D013088 Spermatocele Ethinyl Estradiol 3.9116709447
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.4317007042
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.4318456281
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.4416321402
MESH:D013921 Thrombocytopenia Lipopolysaccharides 4.1215821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1115669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.8712697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 11.7819014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 11.787505956
MESH:D013964 Thyroid Neoplasms Phenobarbital 11.781399818
MESH:D014062 Tongue Neoplasms resveratrol 4.1716227395
MESH:D016171 Torsades de Pointes arsenic trioxide 3.9315213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 2.4612845720 12973940 11780464 20435036
MESH:D014581 Urticaria Acetaminophen 2.9410982225
MESH:D002583 Uterine Cervical Neoplasms resveratrol 4.0617473185
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 9.3614692618
MESH:D014594 Uterine Neoplasms resveratrol 9.3617044934
MESH:D014605 Uveitis Cyclosporine 3.961336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5712125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5015869587 14671159
MESH:D018487 Ventricular Dysfunction, Left resveratrol 4.2617488730
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.2215886252
MESH:D015430 Weight Gain Dietary Fats 3.7016723640
MESH:D014985 Xerophthalmia Cyclosporine 4.4117120751
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA30863
    • No data
    Releated disease ID Related disease Name
    PA444818Lung Neoplasms
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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