AutismKB 2.0

Annotation Detail for DDX58


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Basic Information Top
Gene Symbol:DDX58 ( DKFZp434J1111,DKFZp686N19181,FLJ13599,RIG-I )
Gene Full Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
Band: 9p21.1
Quick LinksEntrez ID:23586; OMIM: 609631; Uniprot ID:DDX58_HUMAN; ENSEMBL ID: ENSG00000107201; HGNC ID: 19102
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa05160Hepatitis C
hsa04622RIG-I-like receptor signaling pathway
hsa04623Cytosolic DNA-sensing pathway
No data
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C097240 15-deoxy-delta(12,14)-prostaglandin J2 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased expression of DDX58 mRNA]decreases reaction|increases expression 16303604
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of DDX58 mRNAincreases expression 19933214
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in decreased expression of DDX58 mRNAdecreases expression 16788091
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of DDX58 mRNAincreases expression 18648102
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of DDX58 mRNAdecreases expression 17484886
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of DDX58 mRNAaffects cotreatment|increases expression 19619570
D004958 Estradiol Estradiol results in increased expression of DDX58 mRNAincreases expression 19619570
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of DDX58 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DDX58 mRNAaffects cotreatment|increases expression 17942748
D008070 Lipopolysaccharides 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased expression of DDX58 mRNA]decreases reaction|increases expression 16303604
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of DDX58 mRNAincreases expression 16303604
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of DDX58 mRNAaffects cotreatment|increases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of DDX58 mRNAincreases expression 19619570
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DDX58 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of DDX58 mRNAincreases expression 19933214
D013876 Thiophenes Thiophenes analog promotes the reaction [Tretinoin results in increased expression of DDX58 mRNA]increases expression|increases reaction 16140955
D014212 Tretinoin Thiophenes analog promotes the reaction [Tretinoin results in increased expression of DDX58 mRNA]increases expression|increases reaction 16140955
D014212 Tretinoin Tretinoin results in increased expression of DDX58 mRNAincreases expression 16140955
D014212 Tretinoin Tretinoin results in decreased expression of DDX58 mRNAdecreases expression 16788091
C025643 vinclozolin vinclozolin affects the expression of DDX58 mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.0011752688 15322242 14514962
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.1217505938
MESH:D055371 Acute Lung Injury Lipopolysaccharides 4.1511850527 18653653
MESH:D000230 Adenocarcinoma Estradiol 4.3011473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.3014692618
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.813712494
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.5316835633
MESH:D000505 Alopecia Tretinoin 3.7015955085
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.0511748828
MESH:D001008 Anxiety Disorders vinclozolin 3.7319015723
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.6011256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.4215885639
MESH:D001169 Arthritis, Experimental Tretinoin 7.4216412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2916292516
MESH:D001249 Asthma Tretinoin 2.3716456186
MESH:D001471 Barrett Esophagus Tretinoin 4.5316935849
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.1911289319 1440618
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 9.3112125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 9.3116206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.9615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.8315746008
MESH:D001943 Breast Neoplasms Estradiol 1.8217289903 18497071 12948864 14630087 16675129 17018787 19861407 17261762
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.8220435547
MESH:D001943 Breast Neoplasms Tretinoin 1.8216166294 16443354 16873071
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.7416813970
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.6216111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.9218705752 15673190 3786805 16227642 10355542 15700767 16097048 16050911 16011737 16192424 16124888 15721981
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8916835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.3316168501
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 6.703581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 6.7018788625
MESH:D006528 Carcinoma, Hepatocellular Estradiol 6.7016924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 6.701917145
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.727296757
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 2.3216096774 16051514
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.4216120746 18670907 18850075
MESH:D002386 Cataract Tretinoin 3.1517460283
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 6.917505956
MESH:D002471 Cell Transformation, Neoplastic Estradiol 6.9118566989
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.7416129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.2616835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 8.1319486331 9022650
MESH:D002779 Cholestasis Ethinyl Estradiol 8.1315861022 16105132 17333356 16919318 11677210 17681005 17110522
MESH:D002822 Choriocarcinoma Tretinoin 5.3316461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.9012621046 15340226 15668235 16354765 8697196
MESH:D002972 Cleft Palate Tretinoin 5.909407595
MESH:D003092 Colitis Tretinoin 3.8417035595
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.1614669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4810048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 2.489142499 10589399 9211117 17551590 9224671 16925845 14991402 9125849 9664655 8800419
MESH:D003456 Cryptorchidism vinclozolin 4.4714966744
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.9411298694 18759878 8970840 8156756 11906362 12868966 2524372 14531868
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.612952479 3621924
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6917107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.5119279558
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 6.359022650 11289319 18289764 18648102 18692083 9653073 8291058 6679447 7440962 9328219 16192314 1440618 6482804
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 6.3519336974 7440962 15968718 4309450 9327722 17522070 11566570 16177239 10092053 16227642 15027814 19085960 15998439 2869522 7120509 3786805 7179309 10915739 6623471 3732212 21278145 6884620
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 6.3520420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.8411462148
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.4811000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 12.5318230668 15322242 16714409
MESH:D004489 Edema, Cardiac Tretinoin 12.5318230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental 15-deoxy-delta(12,14)-prostaglandin J2 9.9216844232
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 9.9212538720
MESH:D016889 Endometrial Neoplasms Estradiol 7.6519148513 18566989 11473722
MESH:D016889 Endometrial Neoplasms Tretinoin 7.6516569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.1210568697 9294722
MESH:D019446 Endotoxemia Lipopolysaccharides 4.5515821434 15328337 17637181
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.133581430
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 9.1111564622
MESH:D005124 Eye Abnormalities Tretinoin 9.119664655 16938888
MESH:D005234 Fatty Liver Carbon Tetrachloride 8.0661145 12631006 16045604 15959796 17595544 16239168 19224547 12795759
MESH:D005234 Fatty Liver Ethinyl Estradiol 8.0615345470
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5911858732
MESH:D005334 Fever Lipopolysaccharides 4.1211852909 9205823
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.196705139
MESH:D005355 Fibrosis Carbon Tetrachloride 15.6018705752
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 15.6020067830
MESH:D005355 Fibrosis Tretinoin 15.6017994277
MESH:D030342 Genetic Diseases, Inborn vinclozolin 5.0916973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.4716417039
MESH:D005909 Glioblastoma Tretinoin 3.0717312396
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.157505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.7710696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.2616096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.3316084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.7211294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 6.729664655 14991402
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 4.4916366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.4411000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 9.656705139
MESH:D006505 Hepatitis Carbon Tetrachloride 9.6519900420 19110552
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.0312621046 15340226 16120746
MESH:D006558 Herpes Genitalis Estradiol 5.2115709030
MESH:D019584 Hot Flashes Estradiol 3.9317088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.228697196 18606429 15340226 16354765 16959395
MESH:D006930 Hyperalgesia Tretinoin 3.3016870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.6916899240
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.7116778211
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.0815034207
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9418850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.2315338365
MESH:D007021 Hypospadias Ethinyl Estradiol 3.9516945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.5812013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.9017937319
MESH:D007248 Infertility, Male vinclozolin 6.9016467254
MESH:D007249 Inflammation Lipopolysaccharides 5.2617255318 12878042 17963957 17237260 9205823
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 5.2612200463 12878042
MESH:D007333 Insulin Resistance Estradiol 3.0316627594 16393666
MESH:D007410 Intestinal Diseases Tretinoin 3.9017994277
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.7517255318
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.198074119 9022650
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 10.3016580747
MESH:D007569 Jaw Abnormalities Tretinoin 10.3015992940 17551590
MESH:D007674 Kidney Diseases Estradiol 2.6415618244
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 7.676582329
MESH:D007680 Kidney Neoplasms Estradiol 7.6715610895
MESH:D007938 Leukemia Tretinoin 2.8217143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.8116932348 19285840 16482212
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0916294345 17596541 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute Thiophenes 8.4616140954 16140955
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 8.4612679006 17649720 17368321 19035177 17301526 19642359 16140955 17712046 17217047 17294898 15748426 17339181 16331271 16823087 16766008 16788101 16935935 17107899 19029980 9834237 17506722 17361223 19075265 16891316 19225113
MESH:D007970 Leukopenia Lipopolysaccharides 4.8515821434
MESH:D007984 Leydig Cell Tumor vinclozolin 4.8916417039
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.389224671
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 2.8617334410 16239168 17174718 21278145 11408273 16221502 16943688 17157831 11903743
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.2615034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 6.8717805973 18376398 18187930 17761835 18395914 16136751 16248980 12666154 16192424 12389079 12632512 18251166 17640975 15730626 15338365 17714472 13678700 16638106 18418968 17698563 15876570 17922224 18412020 18472332 17525996 18472094 18156304 12898905 18210741 12632514 17631135 15052691 12667390 18054572 17766677 17708605 12445421 12546737 17557913 15818738 18166357 18420326 11481614 14716496 20821823 18395095 12586293 17976157 18205269 14716833 14724832 14748882 15650968 18277467 15893842 18006644 15996030 15925388 17900296 15673190 12958196 16011737 18279442 14620537 18429990 16015684 16097048 17481882 17565644 14512876 15362042 15931870 18317297 12609069 18339082 17869086 17944888 12649538 15123356 12445418 16027843 15370692 18705752 18263696 15057751 17823541 16116963 15959796 16033810 10355542 18481824 17721639 12741479
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 6.8714716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 6.8712878042
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 6.8712878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 6.8716248980 18397230
MESH:D008107 Liver Diseases Carbon Tetrachloride 2.1016964402 15830285 15720792 16246199 17285989
MESH:D017093 Liver Failure Carbon Tetrachloride 4.3015123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.7914706259 16899240
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 4.5219294768
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 4.5216984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 10.17598648 6587162 1399818 3712494
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 10.1712014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 10.1712151625
MESH:D055370 Lung Injury Lipopolysaccharides 4.1521114838
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 1.2411884234 19555203
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.6211807958 16891317 11408345 17203775
MESH:D020149 Manganese Poisoning Estradiol 4.6619453300
MESH:D008527 Medulloblastoma Tretinoin 2.8217453147
MESH:D008545 Melanoma Tretinoin 1.9516752155
MESH:D008591 Meningomyelocele Tretinoin 4.5616940565
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.1417596541
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.1112213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.3616810080
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.513581430
MESH:D009369 Neoplasms Tretinoin 2.4616946489 16594593
MESH:D009389 Neovascularization, Pathologic Estradiol 3.8917289903
MESH:D009421 Nervous System Malformations Estradiol 17.1016427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 17.1014600291
MESH:D009421 Nervous System Malformations Tretinoin 17.109125849
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 7.466679447
MESH:D009436 Neural Tube Defects Tretinoin 7.469142499
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.524026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.193988306
MESH:D010051 Ovarian Neoplasms Estradiol 4.9119401270
MESH:D010051 Ovarian Neoplasms Tretinoin 4.9116936753
MESH:D010146 Pain Tretinoin 2.9916870215
MESH:D010190 Pancreatic Neoplasms Tretinoin 2.5015976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.8011578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.627296757
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.4212520081
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.646228378
MESH:D011014 Pneumonia Lipopolysaccharides 4.7111605937 12224865
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.6918163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 10.0111896295 11118676 11399792 11222880
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 10.0118042343 18220299 19015723
MESH:D011469 Prostatic Diseases vinclozolin 5.0918220299
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.9920887781
MESH:D011471 Prostatic Neoplasms Estradiol 3.0716740699
MESH:D011472 Prostatitis vinclozolin 5.0918629315
MESH:D011507 Proteinuria Tretinoin 3.7216636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.4715861022 16919318
MESH:D011625 Pterygium Tretinoin 4.9516723453
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.8010835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.9618990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.463692021
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.2216283617 16116481
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.7216192470
MESH:D012878 Skin Neoplasms Tretinoin 5.7216467112
MESH:D013088 Spermatocele Ethinyl Estradiol 4.1216709447
MESH:D013274 Stomach Neoplasms Tretinoin 1.8017261132
MESH:D013921 Thrombocytopenia Lipopolysaccharides 4.2715821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.7411994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.2515669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.0812697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 7.417505956 6582329 6587162 1399818 3712494
MESH:D013964 Thyroid Neoplasms Tretinoin 7.4117045167 16026305
MESH:D013978 Tibial Fractures Estradiol 4.8619048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.8916051514
MESH:D014376 Tuberculosis Tretinoin 3.2916040207
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 2.318074119
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.7816129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.4214692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.7816752155
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.7712125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.6515869587 14671159
MESH:D014820 Vitiligo Tretinoin 4.1816761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.4215886252
MESH:D009396 Wilms Tumor Tretinoin 4.0716287080
Pathway ID Pathway Name
KEGG:04623 Cytosolic DNA-sensing pathway
KEGG:05160 Hepatitis C
KEGG:05162 Measles
KEGG:04622 RIG-I-like receptor signaling pathway
REACT:25177 RNF125 mediated ubiquitination of RIG-I, MDA5 and IPS-1
REACT:6900 Signaling in Immune system
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA134994272
    • No data
    Releated disease ID Related disease Name
    PA445537Retinitis Pigmentosa
    No data
    Drug Bank Top

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      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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