AutismKB 2.0

Annotation Detail for EID1


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Basic Information Top
Gene Symbol:EID1 ( C15orf3,CRI1,EID-1,IRO45620,MGC138883,MGC138884,PTD014,RBP21 )
Gene Full Name: EP300 interacting inhibitor of differentiation 1
Band: 15q21.1
Quick LinksEntrez ID:23741; OMIM: 605894; Uniprot ID:EID1_HUMAN; ENSEMBL ID: ; HGNC ID: 1191
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of EID1 mRNAaffects expression 17562736
D001104 Arbutin Arbutin results in increased expression of EID1 mRNAincreases expression 17103032
C006632 arsenic trioxide arsenic trioxide results in increased expression of EID1 mRNAincreases expression 20458559
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of EID1 mRNAincreases expression 20106945
C006780 bisphenol A bisphenol A results in increased expression of EID1 mRNAincreases expression 20678512
C006253 pirinixic acid pirinixic acid results in decreased expression of EID1 mRNAdecreases expression 18445702
D012402 Rotenone Rotenone results in decreased expression of EID1 mRNAdecreases expression 19013527
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055371 Acute Lung Injury pirinixic acid 3.4218653653
MESH:D000230 Adenocarcinoma arsenic trioxide 4.5411798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.5420127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 2.806695378
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.8816434500
MESH:D000799 Angioedema Acetaminophen 4.2910982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.4319183758
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 9.9616206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 9.9619483382
MESH:D001862 Bone Resorption bisphenol A 4.1411985600
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.1517474063 20146248
MESH:D001943 Breast Neoplasms bisphenol A 2.1517123778
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.6311589617
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 2.993084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 2.9915553829 16217749 11135700 14691202 15073043
MESH:D002278 Carcinoma in Situ bisphenol A 5.3817123778
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.3219014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.3812490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1120419170
MESH:D002386 Cataract Acetaminophen 2.7310977129
MESH:D002779 Cholestasis pirinixic acid 3.0319176532
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D023903 Coronary Restenosis arsenic trioxide 4.5112609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 1.8910525206
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.4015213294
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5318249437
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6512594235 17906064 16485898 10915739 19164858 11287661 14550746 19739265 11529661 12153990 19420014 10663392 12392966 16227642 12540782 18071297 18713872 12705907 11743745 19416960 11739529 16081117 19923254 14986274 2444490 11421492 16393943 11461765 19370779 11834606 17562736 16109766 15619225 15968718 16177239 17522070 14725611 16781746 19085960 12958197 10774834
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.5419426721
MESH:D004487 Edema pirinixic acid 2.7612083418
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.6312903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.6316530937
MESH:D005234 Fatty Liver arsenic trioxide 8.6715073043
MESH:D005234 Fatty Liver pirinixic acid 8.6719236843 20131406
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.5916904648
MESH:D005756 Gastritis Acetaminophen 4.1216983495
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.7820471113
MESH:D006333 Heart Failure pirinixic acid 2.6920558911
MESH:D006529 Hepatomegaly pirinixic acid 3.3518467677 16221962 19772884 19176532
MESH:D006930 Hyperalgesia Acetaminophen 2.9216870215
MESH:D006943 Hyperglycemia pirinixic acid 3.4520558911
MESH:D007333 Insulin Resistance bisphenol A 7.8816393666
MESH:D007333 Insulin Resistance pirinixic acid 7.8816306350
MESH:D007674 Kidney Diseases Acetaminophen 2.3415629191 12587719
MESH:D007938 Leukemia arsenic trioxide 2.9515070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 4.0817077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.7016972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.6314633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 4.0419077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1716467208 19850784 17050201 16968895 20471514
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.389834237 15336539 15748426 12679006 19642359 11161223 16112521 17217047 16331271 17869043 19035177 16966277 12712474 12018890 16823087 19225113 11468182 16330433 17107899 15622746 17712046 16891316 19075265 17649720 15213294
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.6816882451
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008107 Liver Diseases Acetaminophen 1.6812587719 19460945 11587558 19784758 16610002 12969438 16611625 19014921
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5016871587 17185352
MESH:D008113 Liver Neoplasms arsenic trioxide 7.9214682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 7.9220195826 21137059
MESH:D008113 Liver Neoplasms pirinixic acid 7.9220007298 16377806 15890375
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 2.8920377131
MESH:D008133 Long QT Syndrome arsenic trioxide 3.5615213294
MESH:D008175 Lung Neoplasms arsenic trioxide 2.4811798837 19825857
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 2.4820869020 18569708 6695378 18816296 20064080 20464547 18520028 20135361 17053015
MESH:D008546 Melanoma, Experimental Acetaminophen 3.9319513568
MESH:D008654 Mesothelioma marker/mechanism 15920167
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.4016381670
MESH:D009101 Multiple Myeloma arsenic trioxide 3.2914977855 11468182 19417148 15949261 19549372
MESH:D009135 Muscular Diseases pirinixic acid 3.8616239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 5.1218349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.2816105982 16882451
MESH:D009203 Myocardial Infarction pirinixic acid 2.2419151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.1616411023
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.2916624393
MESH:D009369 Neoplasms Benzo(a)pyrene 5.2211141357
MESH:D009369 Neoplasms pirinixic acid 5.2217405874
MESH:D009410 Nerve Degeneration Rotenone 4.0917356569 15790535 18619942
MESH:D009421 Nervous System Malformations bisphenol A 4.3011399458 16427766
MESH:D009436 Neural Tube Defects arsenic trioxide 3.2810525206
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1018514411
MESH:D009765 Obesity pirinixic acid 1.8620558911
MESH:D010049 Ovarian Diseases bisphenol A 5.3811985600
MESH:D010051 Ovarian Neoplasms arsenic trioxide 2.4719769630 12452020 16624393
MESH:D010146 Pain Acetaminophen 2.6216870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.6015580305
MESH:D010235 Paraganglioma arsenic trioxide 4.4719927285
MESH:D010300 Parkinson Disease Rotenone 3.0619114014 19232380 11445065 16412576 11535288 18191903 15451049 16140633 18619942
MESH:D020734 Parkinsonian Disorders Rotenone 4.3415574749 18197244 15795934 15927086
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 4.3510548101
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 4.4920887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.5119131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.5117292933
MESH:D011471 Prostatic Neoplasms bisphenol A 2.5116740699
MESH:D011629 Puberty, Precocious bisphenol A 5.1810548101
MESH:D015427 Reperfusion Injury pirinixic acid 2.5019058328
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.2916646077
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.4819755658 10029692
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.4217007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.4220155912 2093021
MESH:D019966 Substance-Related Disorders bisphenol A 4.3816045194 16684133
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.2919014326
MESH:D016171 Torsades de Pointes arsenic trioxide 4.3615213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 5.3520435036 11780464 12845720 12973940
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 5.3517053015
MESH:D014581 Urticaria Acetaminophen 3.2810982225
MESH:D014591 Uterine Diseases bisphenol A 5.4514652134
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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