Annotation Detail for PRPF6
Basic Information
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| Gene Symbol: | PRPF6 ( ANT-1,C20orf14,Prp6,TOM,U5-102K,hPrp6 ) |
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| Gene Full Name: | PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) |
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| Band: | 20q13.33 |
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| Quick Links | Entrez ID:24148; OMIM: NA; Uniprot ID:PRP6_HUMAN; ENSEMBL ID: ENSG00000101161; HGNC ID: 15860 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
|---|
| hsa03040 | Spliceosome |
| Pathway ID | Pathway Name |
|---|
| mRNA Processing |
| Gene Expression |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D020111 |
Chlorodiphenyl (54% Chlorine) |
Chlorodiphenyl (54% Chlorine) results in increased expression of PRPF6 mRNA | increases expression | 18178546
|
| D004997 |
Ethinyl Estradiol |
Ethinyl Estradiol affects the expression of PRPF6 mRNA | affects expression | 17555576
|
| D010634 |
Phenobarbital |
Phenobarbital results in decreased expression of PRPF6 mRNA | decreases expression | 19270015
|
| D012643 |
Selenium |
[Selenium co-treated with Vitamin E] results in increased expression of PRPF6 mRNA | affects cotreatment|increases expression | 19244175
|
| D012643 |
Selenium |
Selenium results in increased expression of PRPF6 mRNA | increases expression | 19244175
|
| C021751 |
tanshinone |
tanshinone results in decreased expression of PRPF6 mRNA | decreases expression | 15849732
|
| D014810 |
Vitamin E |
[Selenium co-treated with Vitamin E] results in increased expression of PRPF6 mRNA | affects cotreatment|increases expression | 19244175
|
| D014810 |
Vitamin E |
Vitamin E results in decreased expression of PRPF6 mRNA | decreases expression | 19244175
|
| D014810 |
Vitamin E |
Vitamin E results in increased expression of PRPF6 mRNA | increases expression | 19244175
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
Phenobarbital |
3.90 | 6195326 |
| MESH:D000152 |
Acne Vulgaris |
|
Ethinyl Estradiol |
4.46 | 17505938 |
| MESH:D000230 |
Adenocarcinoma |
|
Ethinyl Estradiol |
1.87 | 14692618 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
Phenobarbital |
4.43 | 17620307 |
| MESH:D001161 |
Arteriosclerosis |
|
Ethinyl Estradiol |
3.88 | 11256880 |
| MESH:D001169 |
Arthritis, Experimental |
|
Ethinyl Estradiol |
2.84 | 15885639 |
| MESH:D001943 |
Breast Neoplasms |
|
tanshinone |
3.60 | 15849732 19885617 |
| MESH:D002252 |
Carbon Tetrachloride Poisoning |
|
Vitamin E |
4.35 | 16050911 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Phenobarbital |
1.94 | 1701930 17173139 20935162 6705139 20007298 |
| MESH:D002493 |
Central Nervous System Diseases |
|
Phenobarbital |
4.67 | 4080065 |
| MESH:D002779 |
Cholestasis |
|
Ethinyl Estradiol |
3.10 | 11677210 16105132 16919318 17333356 15861022 17110522 17681005 |
| MESH:D003092 |
Colitis |
|
Selenium |
4.20 | 17936198 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Vitamin E |
1.92 | 19769572 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Chlorodiphenyl (54% Chlorine) |
4.54 | 17851650 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Selenium |
4.54 | 15131321 |
| MESH:D004421 |
Dystonia |
|
Phenobarbital |
4.36 | 1851702 |
| MESH:C538011 |
Eales disease |
|
Vitamin E |
5.22 | 9068938 |
| MESH:D004681 |
Encephalomyelitis, Autoimmune, Experimental |
|
Ethinyl Estradiol |
3.57 | 12538720 |
| MESH:D004831 |
Epilepsies, Myoclonic |
|
Phenobarbital |
4.53 | 3659116 |
| MESH:D004828 |
Epilepsies, Partial |
|
Phenobarbital |
4.39 | 11558140 3922381 |
| MESH:D004827 |
Epilepsy |
|
Phenobarbital |
3.03 | 20417680 |
| MESH:D004832 |
Epilepsy, Absence |
|
Phenobarbital |
3.83 | 6401628 |
| MESH:D017029 |
Epilepsy, Complex Partial |
|
Phenobarbital |
4.67 | 7750514 |
| MESH:D004830 |
Epilepsy, Tonic-Clonic |
|
Phenobarbital |
4.48 | 3659116 |
| MESH:D005234 |
Fatty Liver |
|
Ethinyl Estradiol |
3.14 | 15345470 |
| MESH:D005910 |
Glioma |
|
tanshinone |
4.13 | 16955220 |
| MESH:D006330 |
Heart Defects, Congenital |
|
Vitamin E |
3.13 | 16080930 |
| MESH:D006333 |
Heart Failure |
|
Selenium |
3.25 | 17162251 |
| MESH:D006529 |
Hepatomegaly |
|
Phenobarbital |
3.90 | 16109766 |
| MESH:D006548 |
Hernia, Diaphragmatic |
|
Vitamin E |
2.79 | 16863852 16490937 |
| MESH:D019584 |
Hot Flashes |
|
Vitamin E |
4.49 | 14716179 |
| MESH:D017379 |
Hypertrophy, Left Ventricular |
|
tanshinone |
5.54 | 19662366 |
| MESH:D007021 |
Hypospadias |
|
Ethinyl Estradiol |
4.23 | 16569931 16945680 |
| MESH:D007247 |
Infertility, Female |
|
Ethinyl Estradiol |
3.81 | 12013081 |
| MESH:D007248 |
Infertility, Male |
|
Ethinyl Estradiol |
2.68 | 17937319 |
| MESH:D007251 |
Influenza, Human |
|
Selenium |
12.76 | 16624496 |
| MESH:D007251 |
Influenza, Human |
|
Vitamin E |
12.76 | 16624496 |
| MESH:D007674 |
Kidney Diseases |
|
Vitamin E |
2.96 | 12488133 |
| MESH:D007676 |
Kidney Failure, Chronic |
|
Selenium |
4.21 | 16518626 |
| MESH:D008103 |
Liver Cirrhosis |
|
Phenobarbital |
3.05 | 21047994 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Vitamin E |
1.90 | 16169303 |
| MESH:D008107 |
Liver Diseases |
|
Phenobarbital |
2.23 | 19363144 |
| MESH:D008113 |
Liver Neoplasms |
|
Phenobarbital |
2.40 | 19812893 21047994 15975961 8742319 19073162 19482888 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
Phenobarbital |
2.88 | 18308698 6150874 1399818 2563599 17172636 |
| MESH:D008171 |
Lung Diseases |
|
Vitamin E |
3.37 | 16863852 |
| MESH:D008175 |
Lung Neoplasms |
|
Vitamin E |
1.90 | 11062179 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Selenium |
2.95 | 15318939 |
| MESH:D008654 |
Mesothelioma |
|
Selenium |
2.89 | 15107826 |
| MESH:D020191 |
Myoclonic Epilepsies, Progressive |
|
Phenobarbital |
4.94 | 17484760 |
| MESH:D010018 |
Osteomalacia |
|
Phenobarbital |
4.83 | 17016548 |
| MESH:D010190 |
Pancreatic Neoplasms |
|
Phenobarbital |
2.58 | 16965848 |
| MESH:D016584 |
Panic Disorder |
|
Ethinyl Estradiol |
4.04 | 11578682 |
| MESH:D010954 |
Plasmacytoma |
|
Selenium |
5.41 | 15087411 |
| MESH:D011230 |
Precancerous Conditions |
|
Phenobarbital |
3.91 | 2563599 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Vitamin E |
3.25 | 15084515 |
| MESH:D011537 |
Pruritus |
|
Ethinyl Estradiol |
3.77 | 16919318 15861022 |
| MESH:D019310 |
Pseudolymphoma |
|
Phenobarbital |
5.02 | 12752131 |
| MESH:D012640 |
Seizures |
|
Phenobarbital |
2.89 | 4039156 3137016 11442880 16876388 |
| MESH:D003294 |
Seizures, Febrile |
|
Phenobarbital |
5.28 | 6407741 |
| MESH:D012871 |
Skin Diseases |
|
Vitamin E |
2.50 | 18709164 |
| MESH:D013088 |
Spermatocele |
|
Ethinyl Estradiol |
4.46 | 16709447 |
| MESH:D020521 |
Stroke |
|
Vitamin E |
3.77 | 16517955 |
| MESH:D019851 |
Thrombophilia |
|
Ethinyl Estradiol |
3.97 | 11994571 |
| MESH:D013927 |
Thrombosis |
|
Ethinyl Estradiol |
3.44 | 15669648 |
| MESH:D013964 |
Thyroid Neoplasms |
|
Phenobarbital |
3.29 | 1399818 |
| MESH:D014594 |
Uterine Neoplasms |
|
Ethinyl Estradiol |
3.68 | 14692618 |
| MESH:D020246 |
Venous Thrombosis |
|
Ethinyl Estradiol |
3.87 | 15869587 14671159 |
PharmGKB Accession:PA25682
| Releated disease ID |
Related disease Name |
| PA447199 | Bipolar Disorder |
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