AutismKB 2.0

Annotation Detail for ABL1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ABL1 ( ABL,JTK7,bcr/abl,c-ABL,p150,v-abl )
Gene Full Name: c-abl oncogene 1, non-receptor tyrosine kinase
Band: 9q34.12
Quick LinksEntrez ID:25; OMIM: 189980; Uniprot ID:ABL1_HUMAN; ENSEMBL ID: ENSG00000097007; HGNC ID: 76
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04012ErbB signaling pathway
hsa04360Axon guidance
hsa05416Viral myocarditis
hsa05131Shigellosis
hsa05130Pathogenic Escherichia coli infection
hsa04722Neurotrophin signaling pathway
hsa04110Cell cycle
hsa05220Chronic myeloid leukemia
hsa05200Pathways in cancer
Pathway IDPathway Name
Myogenesis
Axon guidance
Pathway IDPathway Name
200128Neurotrophic factor-mediated Trk receptor signaling
200127PDGFR-beta signaling pathway
200175p53 pathway
200072Regulation of Telomerase
200114Lissencephaly gene (LIS1) in neuronal migration and development
200191Regulation of retinoblastoma protein
Pathway IDPathway Name
P00008Axon guidance mediated by Slit/Robo
Pathway IDPathway Name
500556CDO in myogenesis
Related Diseases/Disorders Top
Desease IDDesease Name
Cancers of haematopoietic and lymphoid tissues
Cancers
H00004Chronic myeloid leukemia (CML)
H00001Acute lymphoblastic leukemia (ALL) (Precursor B lymphoblastic leukemia)
Desease IDDesease Name
1740Alzheimer's disease
1832Congenital abnormality
1899Eosinophilia
1934Cancer
2052Infection
2087Bacterial infection
2188Bone marrow disease
Desease Name
clonal evolution of chronic myeloid leukemia
CANCER
No data
Desease Name
Leukemia, Philadelphia chromosome-positive, resistant to imatinib
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[BCR protein mutant form binds to ABL1 protein mutant form] which results in increased chemical synthesis of Histamine]affects binding|decreases reaction|increases chemical synthesis 16849647
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[BCR protein mutant form binds to ABL1 protein mutant form] which results in increased expression of HDC mRNA]affects binding|decreases reaction|increases expression 16849647
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in increased expression of ABL1 mRNAincreases expression 16788091
C498826 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide inhibits the reaction [[BCR protein mutant form binds to ABL1 protein mutant form] which results in increased chemical synthesis of Histamine]affects binding|decreases reaction|increases chemical synthesis 16849647
C498826 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide inhibits the reaction [[BCR protein mutant form binds to ABL1 protein mutant form] which results in increased expression of HDC mRNA]affects binding|decreases reaction|increases expression 16849647
C498826 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide results in decreased activity of ABL1 proteindecreases activity 18632630
D000079 Acetaldehyde ABL1 protein promotes the reaction [Acetaldehyde results in increased phosphorylation of and results in decreased activity of PPARG protein]decreases activity|increases phosphorylation|increases reaction 17030193
D000079 Acetaldehyde Acetaldehyde results in increased activity of ABL1 proteinincreases activity 17030193
D000079 Acetaldehyde imatinib inhibits the reaction [Acetaldehyde results in increased activity of ABL1 protein]decreases reaction|increases activity 17030193
D000082 Acetaminophen Acetaminophen affects the expression of ABL1 mRNAaffects expression 17562736
D000638 Amiodarone Amiodarone results in increased expression of ABL1 mRNAincreases expression 19774075
D000643 Ammonium Chloride Ammonium Chloride results in increased expression of ABL1 proteinincreases expression 16483693
C058317 arsenic disulfide arsenic disulfide results in decreased activity of ABL1 proteindecreases activity 12421474
C058317 arsenic disulfide arsenic disulfide results in decreased expression of and results in decreased activity of ABL1 protein mutant formdecreases activity|decreases expression 12421474
C006632 arsenic trioxide arsenic trioxide results in decreased expression of ABL1 mRNAdecreases expression 20458559
C006632 arsenic trioxide arsenic trioxide results in decreased expression of ABL1 protein mutant formdecreases expression 14633726
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ABL1 mRNAdecreases expression 19150397
C471992 bosutinib bosutinib results in decreased activity of ABL1 proteindecreases activity 17114238
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased phosphorylation of ABL1 proteinincreases phosphorylation 17030193
D002251 Carbon Tetrachloride imatinib inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of ABL1 protein]decreases reaction|increases phosphorylation 17030193
D003042 Cocaine Cocaine affects the expression of ABL1 mRNAaffects expression 15681117
C488369 dasatinib dasatinib results in decreased activity of ABL1 proteindecreases activity 17114238
D004967 Estrogens ABL1 protein results in increased susceptibility to Estrogensincreases response to substance 20234815
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of ABL1 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of ABL1 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ABL1 mRNAaffects cotreatment|increases expression 17942748
D006632 Histamine 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[BCR protein mutant form binds to ABL1 protein mutant form] which results in increased chemical synthesis of Histamine]affects binding|decreases reaction|increases chemical synthesis 16849647
D006632 Histamine 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide inhibits the reaction [[BCR protein mutant form binds to ABL1 protein mutant form] which results in increased chemical synthesis of Histamine]affects binding|decreases reaction|increases chemical synthesis 16849647
D006632 Histamine [BCR protein mutant form binds to ABL1 protein mutant form] which results in increased chemical synthesis of Histamineaffects binding|increases chemical synthesis 16849647
D006632 Histamine imatinib inhibits the reaction [[BCR protein mutant form binds to ABL1 protein mutant form] which results in increased chemical synthesis of Histamine]affects binding|decreases reaction|increases chemical synthesis 16849647
D006861 Hydrogen Peroxide Hydrogen Peroxide results in increased activity of ABL1 proteinincreases activity 17030193
D006861 Hydrogen Peroxide imatinib inhibits the reaction [Hydrogen Peroxide results in increased activity of ABL1 protein]decreases reaction|increases activity 17030193
C097613 imatinib imatinib results in decreased phosphorylation of ABL1 proteindecreases phosphorylation 12032135
C097613 imatinib ABL1 mutant form results in increased susceptibility to imatinibincreases response to substance 15107311
C097613 imatinib imatinib inhibits the reaction [Acetaldehyde results in increased activity of ABL1 protein]decreases reaction|increases activity 17030193
C097613 imatinib imatinib inhibits the reaction [[BCR protein mutant form binds to ABL1 protein mutant form] which results in increased chemical synthesis of Histamine]affects binding|decreases reaction|increases chemical synthesis 16849647
C097613 imatinib imatinib inhibits the reaction [[BCR protein mutant form binds to ABL1 protein mutant form] which results in increased expression of HDC mRNA]affects binding|decreases reaction|increases expression 16849647
C097613 imatinib imatinib inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of ABL1 protein]decreases reaction|increases phosphorylation 17030193
C097613 imatinib imatinib inhibits the reaction [Hydrogen Peroxide results in increased activity of ABL1 protein]decreases reaction|increases activity 17030193
C097613 imatinib imatinib results in decreased activity of ABL1 protein mutant formdecreases activity 15329907
C097613 imatinib imatinib results in decreased phosphorylation of ABL1 proteindecreases phosphorylation 12032135
C097613 imatinib imatinib analog results in decreased activity of ABL1 protein modified formdecreases activity 15501042
C097613 imatinib imatinib results in decreased activity of ABL1 proteindecreases activity 16940797
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of ABL1 mRNAincreases expression 12057914
C013592 mangiferin mangiferin results in decreased expression of ABL1 mRNAdecreases expression 15498116
C093973 PD 98059 PD 98059 inhibits the reaction [[ABL1 protein results in increased phosphorylation of and results in decreased activity of PPARG protein] which results in increased expression of COL1A1 protein]decreases activity|decreases reaction|increases expression|increases phosphorylation 17030193
D010634 Phenobarbital Phenobarbital results in decreased methylation of ABL1 promoterdecreases methylation 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of ABL1 mRNAincreases expression 19482888
D010656 Phenylephrine ABL1 protein affects the reaction [Phenylephrine promotes the reaction [BCAR1 protein binds to CRK protein]]affects binding|affects reaction|increases reaction 17615370
D010656 Phenylephrine ABL1 protein affects the reaction [Phenylephrine promotes the reaction [CRK protein binds to WASL protein]]affects binding|affects reaction|increases reaction 17615370
D010656 Phenylephrine ABL1 protein affects the reaction [Phenylephrine results in increased phosphorylation of BCAR1 protein]affects reaction|increases phosphorylation 17615370
D010656 Phenylephrine ABL1 protein affects the susceptibility to Phenylephrineaffects response to substance 17615370
D010656 Phenylephrine Phenylephrine results in increased phosphorylation of ABL1 proteinincreases phosphorylation 17615370
D011189 Potassium Chloride ABL1 protein affects the reaction [Potassium Chloride results in increased phosphorylation of BCAR1 protein]affects reaction|increases phosphorylation 17615370
D011189 Potassium Chloride ABL1 protein affects the susceptibility to Potassium Chlorideaffects response to substance 17615370
D011189 Potassium Chloride Potassium Chloride results in increased phosphorylation of ABL1 proteinincreases phosphorylation 17615370
C487081 PXD101 PXD101 results in decreased expression of ABL1 mRNAdecreases expression 19606018
C085746 rottlerin rottlerin inhibits the reaction [[ABL1 protein results in increased phosphorylation of and results in decreased activity of PPARG protein] which results in increased expression of COL1A1 protein]decreases activity|decreases reaction|increases expression|increases phosphorylation 17030193
C017947 sodium arsenite sodium arsenite results in increased expression of ABL1 mRNAincreases expression 12016162
C017947 sodium arsenite sodium arsenite results in decreased expression of ABL1 mRNAdecreases expression 16014739
D013629 Tamoxifen ABL1 protein results in decreased susceptibility to Tamoxifendecreases response to substance 20234815
D013629 Tamoxifen Tamoxifen affects the expression of ABL1 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ABL1 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of ABL1 mRNAincreases expression 17942748
D014212 Tretinoin Tretinoin results in increased expression of ABL1 mRNAincreases expression 16788091
C012589 trichostatin A trichostatin A results in decreased expression of ABL1 mRNAdecreases expression 19606018
D015032 Zinc Zinc affects the expression of ABL1 proteinaffects expression 16636310
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.2214745880
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 7.226195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.2214514962 11752688 15322242
MESH:D000015 Abnormalities, Multiple imatinib 4.9618322153
MESH:D000022 Abortion, Spontaneous imatinib 5.8818322153
MESH:D000138 Acidosis Ammonium Chloride 3.2318287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.6117505938
MESH:D000169 Acrodermatitis Zinc 5.0816889938 17190629 17202136
MESH:D055371 Acute Lung Injury Lipopolysaccharides 3.7311850527 18653653
MESH:D000230 Adenocarcinoma marker/mechanism 21472143
MESH:D000230 Adenocarcinoma arsenic trioxide 3.9919825857 11798837
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 3.9914692618
MESH:D018248 Adenoma, Liver Cell Phenobarbital 9.0017620307
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.0016835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.3715276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.5716712894 17306315
MESH:D000505 Alopecia Tretinoin 3.3615955085
MESH:D000544 Alzheimer Disease Zinc 2.6816410023 17119284 16580781 16325427
MESH:D000707 Anaphylaxis mangiferin 5.1514669257 16536907
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.6711748828
MESH:D000755 Anemia, Sickle Cell Zinc 4.5916916123
MESH:D000799 Angioedema Acetaminophen 3.5110982225
MESH:D001145 Arrhythmias, Cardiac Amiodarone 8.2118057881 20041841 18218290
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 8.2117460149
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.1511256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.5415885639
MESH:D001169 Arthritis, Experimental Tretinoin 6.5416412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.1916292516
MESH:D001249 Asthma Acetaldehyde 10.559600491
MESH:D001249 Asthma Histamine 10.5516387687
MESH:D001249 Asthma Tretinoin 10.5516456186
MESH:D001249 Asthma Zinc 10.5517085522
MESH:D050197 Atherosclerosis mangiferin 3.9118450471
MESH:D001281 Atrial Fibrillation Amiodarone 3.6618651412 19698954
MESH:D001321 Autistic Disorder Acetaminophen 1.4518445737
MESH:D001471 Barrett Esophagus Tretinoin 4.0916935849
MESH:D001778 Blood Coagulation Disorders Amiodarone 19.5919483382
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 19.5916206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 19.5912125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 19.5916206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.4615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.5615746008
MESH:D001859 Bone Neoplasms imatinib 5.0215867366
MESH:D001862 Bone Resorption mangiferin 4.639881647
MESH:D001919 Bradycardia Phenylephrine 4.2215306635
MESH:D001930 Brain Injuries Zinc 4.3717109824
MESH:D001943 Breast Neoplasms marker/mechanism 20234815
MESH:D001943 Breast Neoplasms imatinib 1.9517614352
MESH:D001943 Breast Neoplasms Tamoxifen 1.9519066611 20390343 20065188 19059307 20135344 19200415 19155303 21152245 16818667 17261762 18425577 19244106 18984771 19103187 18351453 16273361 18629630 19288272 18821012 20859285 19289846 20005174 17242785 20544844 11161223 17893378 18997820 19410462 18855134 19189210 15668708 17049068 19189212 19142967 16873071 21138602 19084267 19011961 19221464 17440819 19487384 15565566 16202921 18815881 19115204
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9520435547
MESH:D001943 Breast Neoplasms Tretinoin 1.9516166294 16443354 16873071
MESH:D001986 Bronchial Spasm Histamine 5.4918298128
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.2616813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.0311589617
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.4616124888 16227642 16097048 15721981 10355542 16192424 3786805 15700767 18705752 15673190 16011737 16050911
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.5516835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.1919066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.8316168501
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 15.893084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 15.8911135700 15073043 15553829 14691202 16217749
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 15.8918788625
MESH:D006528 Carcinoma, Hepatocellular Estrogens 15.8915341023
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 15.891701930 6705139 20007298 17173139 20935162
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 15.8915276417 17306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 15.8916924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 15.891917145
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.5419014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.8412490120
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 7.0318572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 7.0316051514 16096774
MESH:D002294 Carcinoma, Squamous Cell Zinc 7.0316543248
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.3317572228
MESH:D006332 Cardiomegaly Phenylephrine 6.2811754973 15728586 17287366 16170337 11179087 17124262
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.2818670907 18850075 16120746
MESH:D002310 Cardiomyopathy, Alcoholic Acetaldehyde 6.1510525098
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.7815710769 19225199
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 6.9116936243
MESH:D002318 Cardiovascular Diseases Zinc 6.9116936243
MESH:D002341 Carotid Artery Thrombosis Amiodarone 4.7618974383
MESH:D002386 Cataract Acetaminophen 6.5910977129
MESH:D002386 Cataract Tretinoin 6.5917460283
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 5.9920889678
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 5.9920056578 19524636
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.934080065
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.2616129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.8916835633
MESH:D002779 Cholestasis Ethinyl Estradiol 2.6417681005 17110522 16919318 15861022 16105132 17333356 11677210
MESH:D002822 Choriocarcinoma Tretinoin 4.8316461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.3015668235 8697196 12621046 16354765 15340226
MESH:D002972 Cleft Palate Tretinoin 5.309407595
MESH:D019970 Cocaine-Related Disorders Cocaine 5.3919606084
MESH:D003092 Colitis Tretinoin 3.3917035595
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8520501625
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.7914669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 3.8812609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 6.9210525206
MESH:D019465 Craniofacial Abnormalities imatinib 6.9218322153
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 6.9220055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 6.929664655 10589399 9125849 17551590 8800419 16925845 14991402 9224671 9142499 9211117
MESH:D019465 Craniofacial Abnormalities Zinc 6.9219302082
MESH:D016638 Critical Illness Estrogens 5.6216670151
MESH:D003457 Cryptosporidiosis mangiferin 5.5316547730
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.8015213294
MESH:D003711 Demyelinating Diseases Tamoxifen 4.0419031437
MESH:D003920 Diabetes Mellitus Zinc 3.9316479319
MESH:D003921 Diabetes Mellitus, Experimental mangiferin 4.3312093613 19028559
MESH:D003924 Diabetes Mellitus, Type 2 mangiferin 4.409881663 11315760
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.4017107852
MESH:D003928 Diabetic Nephropathies mangiferin 8.4419706694 19960420
MESH:D003928 Diabetic Nephropathies Tamoxifen 8.4419279558
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 8.1010774834 11743745 16109766 12705907 15619225 17906064 17522070 11461765 19420014 18713872 12958197 19416960 16177239 10915739 11421492 11739529 19085960 19739265 11834606 14725611 14986274 18071297 15968718 11287661 16227642 16081117 12540782 16781746 11529661 16393943 2444490 10663392 17562736 19923254 12594235 19370779 16485898 14550746 12153990 12392966 19164858
MESH:D056486 Drug-Induced Liver Injury Amiodarone 8.1015265979 18218290
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 8.102869522 6884620 10092053 3732212 10915739 7120509 15027814 7179309 21278145 6623471 15968718 15998439 9327722 3786805 11566570 4309450 16177239 19336974 7440962 19085960 16227642 17522070
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 8.1020420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.7719426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.5211462148
MESH:D004421 Dystonia Phenobarbital 3.701851702
MESH:D004487 Edema imatinib 6.2819703484
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.2812711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.8415322242 18230668 16714409
MESH:D004489 Edema, Cardiac Tretinoin 10.8418230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 7.9212538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 7.9219031437
MESH:D004701 Endocrine Gland Neoplasms trichostatin A 5.3119294695
MESH:D016889 Endometrial Neoplasms Tamoxifen 6.7317893378 19155303 20544844 16202921
MESH:D016889 Endometrial Neoplasms Tretinoin 6.7316569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.7410568697 9294722
MESH:D019446 Endotoxemia Lipopolysaccharides 4.0717637181 15821434 15328337
MESH:D004802 Eosinophilia Histamine 4.7312689652
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.793659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.543922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.7220417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.276401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.937750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.693659116
MESH:D004938 Esophageal Neoplasms marker/mechanism 21472143
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 6.7920426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 6.7912903497
MESH:D004938 Esophageal Neoplasms Zinc 6.7916543248
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.0411564622
MESH:D005124 Eye Abnormalities Tretinoin 8.049664655 16938888
MESH:D005234 Fatty Liver Amiodarone 26.9514986274
MESH:D005234 Fatty Liver arsenic trioxide 26.9515073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 26.9519224547 16239168 12795759 15959796 12631006 16045604 61145 17595544
MESH:D005234 Fatty Liver Ethinyl Estradiol 26.9515345470
MESH:D005234 Fatty Liver mangiferin 26.9515975614
MESH:D005234 Fatty Liver Tamoxifen 26.9514986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.0416709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.1411858732
MESH:D005334 Fever Lipopolysaccharides 3.7311852909 9205823
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.2014745880
MESH:D018222 Fibromatosis, Aggressive imatinib 10.7417453242
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 10.7419069698
MESH:D005355 Fibrosis Carbon Tetrachloride 12.9218705752
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 12.9220067830
MESH:D005355 Fibrosis Tretinoin 12.9217994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.9516904648
MESH:D005756 Gastritis Acetaminophen 10.0616983495
MESH:D005756 Gastritis Zinc 10.0617241300
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.3516452187
MESH:D005909 Glioblastoma Tretinoin 6.7217312396
MESH:D005909 Glioblastoma trichostatin A 6.7218801729
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.2610696789
MESH:D006130 Growth Disorders Zinc 3.7517217573
MESH:D006258 Head and Neck Neoplasms Tretinoin 2.9716096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.8316084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 5.9611294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 5.969664655 14991402
MESH:D006331 Heart Diseases mangiferin 4.1712093613
MESH:D006333 Heart Failure Zinc 3.4117162251
MESH:D006335 Heart Injuries Zinc 5.4417074742
MESH:D016481 Helicobacter Infections Zinc 4.2317241300
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 4.1016366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.0511000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.2919900420 19110552
MESH:D006527 Hepatolenticular Degeneration Zinc 4.3717276780
MESH:D006529 Hepatomegaly Amiodarone 12.6415265979
MESH:D006529 Hepatomegaly Phenobarbital 12.6416109766
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 12.6416120746 15340226 12621046
MESH:D006561 Herpes Simplex mangiferin 4.6810715843
MESH:D006689 Hodgkin Disease sodium arsenite 2.8912676792
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.7118606429 15340226 16354765 8697196 16959395
MESH:D006930 Hyperalgesia Acetaminophen 6.7816870215
MESH:D006930 Hyperalgesia Tretinoin 6.7816870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.2116899240
MESH:D006937 Hypercholesterolemia Amiodarone 3.588137927 9751232
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.2516778211
MESH:D006946 Hyperinsulinism mangiferin 4.739881663 11315760
MESH:D006949 Hyperlipidemias mangiferin 4.5515975614
MESH:D006967 Hypersensitivity mangiferin 4.4116536907
MESH:D006973 Hypertension Phenylephrine 4.8812717712 8949925
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.8818670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.7715338365
MESH:D006984 Hypertrophy Phenylephrine 4.2612791704 18502941
MESH:D007021 Hypospadias Ethinyl Estradiol 3.4916945680 16569931
MESH:D007037 Hypothyroidism Amiodarone 4.2018020914 17991464
MESH:D007154 Immune System Diseases mangiferin 5.5316076520
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.1612013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 5.9217937319
MESH:D007248 Infertility, Male sodium arsenite 5.9215346721 12646999
MESH:D007249 Inflammation Lipopolysaccharides 10.6117255318 12878042 17963957 17237260 9205823
MESH:D007249 Inflammation mangiferin 10.6115222974
MESH:D007249 Inflammation Tamoxifen 10.6119457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 10.6112200463 12878042
MESH:D007333 Insulin Resistance mangiferin 4.1311315760
MESH:D007410 Intestinal Diseases Tretinoin 3.4517994277
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.3317255318
MESH:D007511 Ischemia mangiferin 10.1716806951
MESH:D007511 Ischemia Zinc 10.1716584753
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 8.9716580747
MESH:D007569 Jaw Abnormalities Tretinoin 8.9715992940 17551590
MESH:D007674 Kidney Diseases Acetaminophen 12.9715629191 12587719
MESH:D007674 Kidney Diseases mangiferin 12.9712093613
MESH:D007674 Kidney Diseases sodium arsenite 12.9720008137
MESH:D007674 Kidney Diseases Zinc 12.9716960431
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 9.2616518626
MESH:D007676 Kidney Failure, Chronic Zinc 9.2616518626
MESH:D007680 Kidney Neoplasms Tamoxifen 2.7918625569
MESH:D007859 Learning Disorders mangiferin 4.6419182383
MESH:D007938 Leukemia 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 9.6412970779
MESH:D007938 Leukemia arsenic trioxide 9.6415070760
MESH:D007938 Leukemia Tretinoin 9.6417143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.5117077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 10.6416972261
MESH:D007948 Leukemia, Monocytic, Acute PD 98059 10.6416972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic disulfide 18.1912421474
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 18.1914633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive imatinib 18.1915748426 17301526 15107311 19208803
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive mangiferin 18.1915498116
MESH:D007951 Leukemia, Myeloid arsenic trioxide 14.4719077051
MESH:D007951 Leukemia, Myeloid imatinib 14.4717236224
MESH:D007951 Leukemia, Myeloid Tretinoin 14.4719285840 16482212 16932348
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 5.8316467208 17050201 16968895 20471514 19850784
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 5.8319850784 16294345 17596541
MESH:D015470 Leukemia, Myeloid, Acute trichostatin A 5.8318206229
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 6.9317712046 11468182 17649720 17107899 15622746 19642359 16823087 19035177 9834237 16112521 17869043 12018890 16891316 11161223 12679006 17217047 19075265 16331271 15213294 15748426 12712474 15336539 19225113 16966277 16330433
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 6.9317361223 17506722 19075265 16331271 17301526 16766008 16788101 17368321 19225113 17217047 16935935 15748426 16823087 12679006 16891316 19642359 19029980 19035177 17339181 16140955 17294898 9834237 17649720 17712046 17107899
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.0416882451
MESH:D007970 Leukopenia Lipopolysaccharides 4.3715821434
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.089224671
MESH:D008064 Lipidoses Amiodarone 7.1517567588 15342952
MESH:D008064 Lipidoses Tamoxifen 7.1515342952 17567588
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 6.0316239168 17174718 16221502 21278145 11903743 17334410 17157831 11408273 16943688
MESH:D008103 Liver Cirrhosis Phenobarbital 6.0321047994
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 8.1512958196 16033810 16116963 16638106 18395914 15650968 15123356 11481614 12898905 17900296 15362042 15959796 17640975 18472094 15338365 17869086 18412020 17976157 18339082 14716833 17944888 18166357 17557913 16136751 12546737 17922224 12632514 17481882 17721639 16011737 15057751 12649538 18187930 18263696 15996030 14724832 16248980 18420326 17631135 16097048 13678700 20821823 16192424 18054572 15730626 18481824 17525996 12445418 17805973 15931870 18418968 12609069 12667390 15052691 18429990 15893842 18317297 18395095 18156304 18251166 12445421 17708605 18279442 18472332 12632512 14716496 10355542 18006644 15673190 14620537 17766677 17761835 15876570 15818738 12586293 15925388 18210741 17698563 12741479 12389079 17565644 14748882 18205269 16015684 16027843 14512876 18705752 15370692 17714472 12666154 17823541 18376398 18277467
MESH:D008106 Liver Cirrhosis, Experimental imatinib 8.1516596278
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 8.1512878042
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 8.1518564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 8.1512878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 8.1518397230 16248980
MESH:D008107 Liver Diseases Acetaminophen 5.9416611625 12969438 11587558 19784758 19014921 12587719 19460945 16610002
MESH:D008107 Liver Diseases Carbon Tetrachloride 5.9416964402 15830285 16246199 15720792 17285989
MESH:D008107 Liver Diseases Phenobarbital 5.9419363144
MESH:D017093 Liver Failure Carbon Tetrachloride 3.8515123358
MESH:D017114 Liver Failure, Acute Acetaminophen 8.4717185352 16871587
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 8.4716899240 14706259
MESH:D008113 Liver Neoplasms arsenic trioxide 16.2914682389
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 16.2919294768
MESH:D008113 Liver Neoplasms Phenobarbital 16.298742319 19073162 19482888 21047994 19812893 15975961
MESH:D008113 Liver Neoplasms sodium arsenite 16.2916712894 15276417
MESH:D008113 Liver Neoplasms Tamoxifen 16.2916684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 16.2916984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 12.4420377131
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 12.4415583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 12.441399818 6150874 2563599 17172636 18308698
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 12.4412151625
MESH:D008133 Long QT Syndrome Amiodarone 7.3817391786 15350150 11989578
MESH:D008133 Long QT Syndrome arsenic trioxide 7.3815213294
MESH:D008171 Lung Diseases Amiodarone 6.7912587719
MESH:D008171 Lung Diseases sodium arsenite 6.7919095001
MESH:D017563 Lung Diseases, Interstitial Amiodarone 4.1518516814
MESH:D055370 Lung Injury Lipopolysaccharides 3.6921114838
MESH:D008175 Lung Neoplasms Acetaldehyde 7.9817372256
MESH:D008175 Lung Neoplasms arsenic trioxide 7.9819825857 11798837
MESH:D008175 Lung Neoplasms mangiferin 7.9818520028 18569708 18816296
MESH:D008175 Lung Neoplasms sodium arsenite 7.9816712894 17077188 19931552 17306315 15276417
MESH:D008175 Lung Neoplasms Tamoxifen 7.9818625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 7.9819555203 11884234
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.4419428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 5.5514580682 16827153 11731420 19196723 19196722
MESH:D008325 Mammary Neoplasms, Experimental Zinc 5.5512773700
MESH:D020149 Manganese Poisoning Tamoxifen 4.2219453300
MESH:D008527 Medulloblastoma Tretinoin 2.6517453147
MESH:D008545 Melanoma Histamine 9.1317709802
MESH:D008545 Melanoma sodium arsenite 9.1316487513 19082730
MESH:D008545 Melanoma Tamoxifen 9.1319393235 12393984
MESH:D008545 Melanoma Tretinoin 9.1316752155
MESH:D008545 Melanoma trichostatin A 9.1316505122
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.8615990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.2519513568
MESH:D008569 Memory Disorders mangiferin 4.6219182383
MESH:D008591 Meningomyelocele Tretinoin 4.1116940565
MESH:D009101 Multiple Myeloma arsenic trioxide 6.8015949261 14977855 19417148 19549372 11468182
MESH:D009101 Multiple Myeloma trichostatin A 6.8018172295
MESH:D009181 Mycoses Amiodarone 4.5717974566 12754197
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.3418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 6.7716882451 16105982
MESH:D009190 Myelodysplastic Syndromes Tretinoin 6.7717596541
MESH:D009203 Myocardial Infarction Cocaine 6.2518072171
MESH:D009203 Myocardial Infarction mangiferin 6.2516584858 17052832 16697266 19172585 16538859
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.7612213967
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.1517484760
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.6516624393
MESH:D009362 Neoplasm Metastasis imatinib 5.8115867366
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.8119393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4119410462
MESH:D009369 Neoplasms sodium arsenite 4.5711559025
MESH:D009369 Neoplasms Tretinoin 4.5716946489 16594593
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.3520056578
MESH:D009376 Neoplasms, Hormone-Dependent imatinib 10.0817614352
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 10.0819200415 19196722 19189210
MESH:D009410 Nerve Degeneration mangiferin 4.3717433543
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 8.4814600291
MESH:D009421 Nervous System Malformations Tretinoin 8.489125849
MESH:D009436 Neural Tube Defects arsenic trioxide 10.9310525206
MESH:D009436 Neural Tube Defects sodium arsenite 10.9312854658
MESH:D009436 Neural Tube Defects Tretinoin 10.939142499
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.6118514411
MESH:D010014 Osteolysis imatinib 5.4115867366
MESH:D010018 Osteomalacia Phenobarbital 4.0417016548
MESH:D010051 Ovarian Neoplasms 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 13.8416211241
MESH:D010051 Ovarian Neoplasms arsenic trioxide 13.8416624393 12452020 19769630
MESH:D010051 Ovarian Neoplasms sodium arsenite 13.8415276417 17306315
MESH:D010051 Ovarian Neoplasms Tretinoin 13.8416936753
MESH:D010051 Ovarian Neoplasms trichostatin A 13.8419331143
MESH:D010146 Pain Acetaminophen 5.7316870215
MESH:D010146 Pain Tretinoin 5.7316870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 11.3515580305
MESH:D010190 Pancreatic Neoplasms Phenobarbital 11.3516965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 11.3515976015
MESH:D010190 Pancreatic Neoplasms trichostatin A 11.3519294695
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.3911578682
MESH:D010212 Papilloma Hydrogen Peroxide 3.7712065085
MESH:D010235 Paraganglioma arsenic trioxide 3.8619927285
MESH:D010300 Parkinson Disease mangiferin 3.5917433543
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.9212520081
MESH:D010518 Periodontitis mangiferin 5.2719026997
MESH:D011014 Pneumonia Lipopolysaccharides 4.2312224865 11605937
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.2518163543
MESH:D011230 Precancerous Conditions Phenobarbital 3.352563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma imatinib 4.3012476293
MESH:D011225 Pre-Eclampsia Zinc 3.9317114810
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 2.8711222880 11896295 11399792 11118676
MESH:D055728 Primary Myelofibrosis trichostatin A 4.9317616702
MESH:D011471 Prostatic Neoplasms arsenic trioxide 1.9119131511
MESH:D011471 Prostatic Neoplasms sodium arsenite 1.9116039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 1.9115067354
MESH:D011471 Prostatic Neoplasms trichostatin A 1.9119789329 18798265
MESH:D011471 Prostatic Neoplasms Zinc 1.9112429649 16700911 16606632 16517595
MESH:D011507 Proteinuria Tretinoin 3.3116636307
MESH:D011537 Pruritus Ethinyl Estradiol 2.9915861022 16919318
MESH:D019310 Pseudolymphoma Phenobarbital 4.1612752131
MESH:D011618 Psychotic Disorders Cocaine 4.5916134406
MESH:D011625 Pterygium Tretinoin 4.4716723453
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.7311597910 12490602 12832656
MESH:D011833 Radiation Injuries, Experimental mangiferin 6.0815830843
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.5210835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.5318990726
MESH:D012162 Retinal Degeneration Zinc 3.8916584753
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.8016116481 16283617
MESH:D012220 Rhinitis Acetaldehyde 8.6517050345
MESH:D012220 Rhinitis Histamine 8.6512689652
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.6516646077
MESH:D012640 Seizures Cocaine 5.7510454489
MESH:D012640 Seizures Phenobarbital 5.754039156 16876388 3137016 11442880
MESH:D003294 Seizures, Febrile Phenobarbital 4.506407741
MESH:D012772 Shock, Septic mangiferin 4.9115177305
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 4.7618724381
MESH:D012852 Sinusitis Phenylephrine 4.387327846
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 12.2812065085
MESH:D012878 Skin Neoplasms sodium arsenite 12.2819524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 12.2816192470
MESH:D012878 Skin Neoplasms Tretinoin 12.2816467112
MESH:D013088 Spermatocele Ethinyl Estradiol 10.4616709447
MESH:D013088 Spermatocele Tamoxifen 10.4616709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.7119457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.5512854658
MESH:D013274 Stomach Neoplasms arsenic trioxide 3.3717007042
MESH:D013274 Stomach Neoplasms imatinib 3.3715786421
MESH:D013274 Stomach Neoplasms Tretinoin 3.3717261132
MESH:D013276 Stomach Ulcer Amiodarone 6.8118087811
MESH:D013276 Stomach Ulcer mangiferin 6.8117918041
MESH:D013610 Tachycardia Amiodarone 3.9811238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 3.8819225199
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.8815821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.3211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.8815669648
MESH:D013959 Thyroid Diseases Amiodarone 10.9519731979
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 10.9512697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 15.1619014326
MESH:D013964 Thyroid Neoplasms imatinib 15.1616940797
MESH:D013964 Thyroid Neoplasms Phenobarbital 15.161399818
MESH:D013964 Thyroid Neoplasms Tretinoin 15.1617045167 16026305
MESH:D013971 Thyrotoxicosis Amiodarone 4.5419584973 18020914
MESH:D014062 Tongue Neoplasms Tretinoin 9.0416051514
MESH:D014062 Tongue Neoplasms Zinc 9.0416543248
MESH:D016171 Torsades de Pointes Amiodarone 9.1817467628 11989578
MESH:D016171 Torsades de Pointes arsenic trioxide 9.1815213294
MESH:D014235 Trichinellosis mangiferin 5.7314669257
MESH:D014376 Tuberculosis Tretinoin 3.0316040207
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 7.5711780464 20435036 12845720 12973940
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 7.5717306315 16712894 11723127 16452187
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 7.5717572228 8653321 16712894
MESH:D014581 Urticaria Acetaminophen 8.1310982225
MESH:D014581 Urticaria Histamine 8.1318298128
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 8.4811813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 8.4816129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 2.9914692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.2816752155
MESH:D014652 Vascular Diseases sodium arsenite 4.1017056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.2612125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.2514671159 15869587
MESH:D014820 Vitiligo Tretinoin 3.7516761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.9215886252
MESH:D009396 Wilms Tumor Tretinoin 3.6916287080
MESH:D014947 Wounds and Injuries Estrogens 4.4811172683
Pathway ID Pathway Name
KEGG:04360 Axon guidance
REACT:18266 Axon guidance
KEGG:04110 Cell cycle
KEGG:05220 Chronic myeloid leukemia
KEGG:04012 ErbB signaling pathway
REACT:604 Hemostasis
REACT:21303 Myogenesis
KEGG:04722 Neurotrophin signaling pathway
KEGG:05130 Pathogenic Escherichia coli infection
KEGG:05200 Pathways in cancer
KEGG:05131 Shigellosis
KEGG:05416 Viral myocarditis
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA24413
    • No data
    Releated disease ID Related disease Name
    PA443622Carcinoma, Non-Small-Cell Lung
    PA446661Carcinoma, Small Cell
    PA444818Lung Neoplasms
    PA445062Neoplasms
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    PA446171Leukemia, Myelogenous, Chronic, BCR-ABL Positive
    PA443890Diabetes Mellitus, Type 2
    PA444761Leukemia, Myeloid
    Releated drug ID Related drug Name
    PA131301952gefitinib
    PA449014cisplatin
    PA10804imatinib
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00171 inhibitor Adenosine triphosphate Dietary supplement;Micronutrient
    DB00619 inhibitor Imatinib Antineoplastic Agents;Protein Kinase Inhibitors
    DB01254 multitarget Dasatinib Protein Kinase Inhibitors
    DB03878 - N-[4-Methyl-3-[[4-(3-Pyridinyl)-2-Pyrimidinyl]Amino]Phenyl]-3-Pyridinecarboxamide
    DB04868 antagonist Nilotinib Anticancer Agents
    DB07831 - 2-{[(6-OXO-1,6-DIHYDROPYRIDIN-3-YL)METHYL]AMINO}-N-[4-PROPYL-3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE
    DB08043 - 1-[4-(PYRIDIN-4-YLOXY)PHENYL]-3-[3-(TRIFLUOROMETHYL)PHENYL]UREA
    DB08231 - MYRISTIC ACID
    DB08339 - 6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE
    DB08350 - 5-[3-(2-METHOXYPHENYL)-1H-PYRROLO[2,3-B]PYRIDIN-5-YL]-N,N-DIMETHYLPYRIDINE-3-CARBOXAMIDE
    DB08583 - 2-amino-5-[3-(1-ethyl-1H-pyrazol-5-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethylbenzamide
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


    Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved