AutismKB 2.0

Annotation Detail for NEIL2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:NEIL2 ( FLJ31644,MGC2832,MGC4505,NEH2,NEI2 )
Gene Full Name: nei endonuclease VIII-like 2 (E. coli)
Band: 8p23.1
Quick LinksEntrez ID:252969; OMIM: 608933; Uniprot ID:NEIL2_HUMAN; ENSEMBL ID: ENSG00000154328; HGNC ID: 18956
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa03410Base excision repair
No data
No data
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1976Squamous cell cancer
2053Colon cancer
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D015025 Zearalenone Zearalenone results in increased expression of NEIL2 mRNAincreases expression 19371625
D019833 Genistein Genistein results in increased expression of NEIL2 mRNAincreases expression 19371625
C016340 o,p'-DDT o,p'-DDT results in increased expression of NEIL2 mRNAincreases expression 19371625
C059514 resveratrol resveratrol results in increased expression of NEIL2 mRNAincreases expression 19371625
D014501 Uranium Uranium affects the expression of NEIL2 mRNAaffects expression 15672453
C005460 uranyl acetate uranyl acetate affects the expression of NEIL2 mRNAaffects expression 15672453
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D058186 Acute Kidney Injury resveratrol 4.1716538975
MESH:D000230 Adenocarcinoma Genistein 2.5411473722
MESH:D000236 Adenoma resveratrol 3.4815688382
MESH:D000544 Alzheimer Disease resveratrol 2.6216162502 16183991
MESH:D001169 Arthritis, Experimental resveratrol 3.6817115116
MESH:D050197 Atherosclerosis resveratrol 3.4417967414 16873680
MESH:D002545 Brain Ischemia resveratrol 4.7517600658
MESH:D001943 Breast Neoplasms Genistein 2.4116873071 16541309 17200150
MESH:D001943 Breast Neoplasms resveratrol 2.4117534123 16393696 17651959
MESH:D006528 Carcinoma, Hepatocellular Genistein 3.4216924424
MESH:D006528 Carcinoma, Hepatocellular resveratrol 3.4216227395 19321006
MESH:D018827 Carcinoma, Lewis Lung resveratrol 5.0516675471
MESH:D002294 Carcinoma, Squamous Cell resveratrol 2.7816227395
MESH:D002318 Cardiovascular Diseases Genistein 8.2216332659
MESH:D002318 Cardiovascular Diseases resveratrol 8.2215458977
MESH:D003092 Colitis resveratrol 4.5416474422
MESH:D003110 Colonic Neoplasms Genistein 4.0917182828
MESH:D003110 Colonic Neoplasms resveratrol 4.0916338953
MESH:D015179 Colorectal Neoplasms resveratrol 2.2316550006
MESH:D003327 Coronary Disease resveratrol 3.9416507316
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 4.0416873680
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 2.5416647724
MESH:D003928 Diabetic Nephropathies resveratrol 4.2516286809
MESH:D004487 Edema resveratrol 3.698985016
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 4.4117872969
MESH:D004714 Endometrial Hyperplasia Genistein 5.0516402032
MESH:D016889 Endometrial Neoplasms Genistein 3.5511473722
MESH:D020345 Enterocolitis, Necrotizing resveratrol 5.2717923197
MESH:D005909 Glioblastoma Genistein 3.4516598420
MESH:D006561 Herpes Simplex resveratrol 4.6416876885
MESH:D006937 Hypercholesterolemia resveratrol 4.3317188708
MESH:D006949 Hyperlipidemias resveratrol 4.3816873680
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.6117488730
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 5.0617600658
MESH:D007249 Inflammation resveratrol 2.9816366677
MESH:D007251 Influenza, Human resveratrol 5.0616624496
MESH:D007938 Leukemia Genistein 3.1617468513 18980019
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 3.7716087638
MESH:D008106 Liver Cirrhosis, Experimental Genistein 2.0617823541
MESH:D008113 Liver Neoplasms resveratrol 2.8019812893 19321006 19073162 20405173
MESH:D016393 Lymphoma, B-Cell resveratrol 4.6517088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 4.1414749477
MESH:D015674 Mammary Neoplasms, Animal resveratrol 4.7115688416
MESH:D008325 Mammary Neoplasms, Experimental Genistein 6.9214578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 6.9211606380 8985016
MESH:D008545 Melanoma resveratrol 2.4017992120
MESH:D008659 Metabolic Diseases resveratrol 4.7017112576
MESH:D009101 Multiple Myeloma resveratrol 3.6817935668 16490592 16267019 14749477 17164350 17049120
MESH:D009134 Muscular Atrophy, Spinal resveratrol 5.3317962980
MESH:D009203 Myocardial Infarction Genistein 6.3717141266
MESH:D009203 Myocardial Infarction resveratrol 6.3716317513 16525036 16456233 17188708 17015251 17125593
MESH:D017202 Myocardial Ischemia resveratrol 4.2617015251 17125593
MESH:D015428 Myocardial Reperfusion Injury Genistein 3.9017141266
MESH:D009205 Myocarditis resveratrol 5.2217322642
MESH:D009374 Neoplasms, Experimental resveratrol 4.428985016
MESH:D009421 Nervous System Malformations Genistein 4.4116427766
MESH:D019636 Neurodegenerative Diseases resveratrol 4.0717652729
MESH:D020078 Neurogenic Inflammation resveratrol 4.7517929310
MESH:D010024 Osteoporosis Genistein 3.4319401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 11.3516169203
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 11.3517513867
MESH:D010051 Ovarian Neoplasms Genistein 2.6719005980
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 4.6416679765
MESH:D011471 Prostatic Neoplasms Genistein 3.4215256057 16925846 15378649
MESH:D011471 Prostatic Neoplasms resveratrol 3.4216731767 17804756 17718901 17636462 17675339 15767336
MESH:D051436 Renal Insufficiency, Chronic resveratrol 6.1016325855
MESH:D015427 Reperfusion Injury resveratrol 3.4016314181 17520802 17058453 16317513 15827377
MESH:D012878 Skin Neoplasms resveratrol 3.168985016 15837718
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.7816321402
MESH:D014062 Tongue Neoplasms resveratrol 4.5216227395
MESH:D002583 Uterine Cervical Neoplasms resveratrol 4.4117473185
MESH:D014594 Uterine Neoplasms resveratrol 4.5217044934
MESH:D018487 Ventricular Dysfunction, Left resveratrol 4.7217488730
Pathway ID Pathway Name
KEGG:03410 Base excision repair
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved