AutismKB 2.0

Annotation Detail for MCM9


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Basic Information Top
Gene Symbol:MCM9 ( C6orf61,FLJ13942,FLJ20170,FLJ56845,MCMDC1,MGC35304,dJ329L24.1,dJ329L24.3 )
Gene Full Name: minichromosome maintenance complex component 9
Band: 6q22.31
Quick LinksEntrez ID:254394; OMIM: 610098; Uniprot ID:MCM9_HUMAN; ENSEMBL ID: ENSG00000111877; HGNC ID: 21484
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of MCM9 mRNAaffects expression 17562736
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of MCM9 mRNAdecreases expression 19150397
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.9110982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.8310977129
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 3.0420889678
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6816781746 15619225 11461765 18713872 11287661 12594235 14986274 10774834 11834606 14550746 12153990 19164858 16081117 12392966 12705907 11529661 10915739 15968718 17906064 19085960 19416960 11743745 14725611 19420014 12958197 12540782 10663392 17562736 18071297 11739529 16227642 2444490 16109766 16485898 19739265 19923254 17522070 19370779 11421492 16177239 16393943
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.1719426721
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1620426865
MESH:D005756 Gastritis Acetaminophen 4.7416983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1116870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4415629191 12587719
MESH:D008107 Liver Diseases Acetaminophen 1.7119014921 16610002 12969438 16611625 19784758 12587719 19460945 11587558
MESH:D017114 Liver Failure, Acute Acetaminophen 3.7417185352 16871587
MESH:D008546 Melanoma, Experimental Acetaminophen 4.3319513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3118514411
MESH:D010146 Pain Acetaminophen 2.8216870215
MESH:D014581 Urticaria Acetaminophen 3.5810982225
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018