AutismKB 2.0

Annotation Detail for C10orf47


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Basic Information Top
Gene Symbol:C10orf47 ( MGC35403 )
Gene Full Name: chromosome 10 open reading frame 47
Band: 10p14
Quick LinksEntrez ID:254427; OMIM: NA; Uniprot ID:CJ047_HUMAN; ENSEMBL ID: ENSG00000148426; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
D000638 Amiodarone Amiodarone results in increased expression of C10ORF47 mRNAincreases expression 19774075
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of C10ORF47 mRNAdecreases expression 19150397
D016572 Cyclosporine Cyclosporine results in increased expression of C10ORF47 mRNAincreases expression 20106945
D014635 Valproic Acid Valproic Acid results in increased expression of C10ORF47 mRNAincreases expression 19101580
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 4.118875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 4.3519490988
MESH:D000550 Amblyopia Valproic Acid 5.9617688650
MESH:D001008 Anxiety Disorders Valproic Acid 3.9017497229
MESH:D001145 Arrhythmias, Cardiac Amiodarone 4.2020041841 18218290 18057881
MESH:D001281 Atrial Fibrillation Amiodarone 4.2018651412 19698954
MESH:D001321 Autistic Disorder Valproic Acid 1.9818396377 17688650 18177632 17507914 18940202 18985861 16609825 18558336 18775368 18316065 19460635 17157402 20603192 19232924 15238991
MESH:D001714 Bipolar Disorder Valproic Acid 3.2420046352 17594078
MESH:D001778 Blood Coagulation Disorders Amiodarone 4.3219483382
MESH:D001848 Bone Diseases, Developmental Valproic Acid 3.638888407
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 3.0019225199 15710769
MESH:D002341 Carotid Artery Thrombosis Amiodarone 5.7218974383
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.4420889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 7.4412371664
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.8220734317
MESH:D002779 Cholestasis Cyclosporine 3.2119486331
MESH:D019465 Craniofacial Abnormalities Valproic Acid 1.9117688650 16575769 8888407
MESH:D056486 Drug-Induced Liver Injury Amiodarone 4.3918218290 15265979
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 4.3919641884 1733752
MESH:D004421 Dystonia Valproic Acid 4.511851702
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.7117275665 3659116
MESH:D004828 Epilepsies, Partial Valproic Acid 4.6416628512 3922381
MESH:D004827 Epilepsy Valproic Acid 3.1120417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 3.966426943 7562514 6254150
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.867750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.693659116
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1520426865
MESH:D005234 Fatty Liver Amiodarone 15.7614986274
MESH:D005234 Fatty Liver Cyclosporine 15.7619224547
MESH:D005234 Fatty Liver Valproic Acid 15.7614986274 19224547
MESH:D005315 Fetal Diseases Valproic Acid 5.6116575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.6418558336 8888407
MESH:D005355 Fibrosis Cyclosporine 3.7012639820 12168785
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.858708960
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 5.0515720958
MESH:D006529 Hepatomegaly Amiodarone 4.3115265979
MESH:D006849 Hydrocephalus Valproic Acid 5.5017688650
MESH:D006937 Hypercholesterolemia Amiodarone 4.308137927 9751232
MESH:D006973 Hypertension Cyclosporine 2.2110903974
MESH:D007037 Hypothyroidism Amiodarone 5.0817991464 18020914
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.1615604871
MESH:D007674 Kidney Diseases Cyclosporine 2.548314463 10903974 18776723
MESH:D007680 Kidney Neoplasms Cyclosporine 3.0812371664
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.2016294345 17596541
MESH:D008064 Lipidoses Amiodarone 3.7917567588 15342952
MESH:D008133 Long QT Syndrome Amiodarone 3.8917391786 15350150 11989578
MESH:D008171 Lung Diseases Amiodarone 3.6212587719
MESH:D017563 Lung Diseases, Interstitial Amiodarone 13.8118516814
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 13.8117228818
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.5116801185
MESH:D008881 Migraine Disorders Valproic Acid 3.4718803445 18765137
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.458888407
MESH:D009181 Mycoses Amiodarone 5.6217974566 12754197
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.3517596541
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.1617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.6519348381 18481113
MESH:D009436 Neural Tube Defects Valproic Acid 3.3716359493 8888407
MESH:D011230 Precancerous Conditions Cyclosporine 3.5912371664
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 4.4620603192
MESH:D019310 Pseudolymphoma Valproic Acid 5.2612752131 11422049
MESH:D011565 Psoriasis Cyclosporine 2.3316882103
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.9712832656 12490602 11597910
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.6419155313
MESH:D012559 Schizophrenia Valproic Acid 2.1015737665 19110320
MESH:D012640 Seizures Valproic Acid 2.9911738929 16876388 11044598 14763951 3137016 15475178 1511512 17978042
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 5.7218724381
MESH:D016135 Spinal Dysraphism Valproic Acid 4.0919490988
MESH:D013226 Status Epilepticus Valproic Acid 5.2612833885
MESH:D013276 Stomach Ulcer Amiodarone 3.7418087811
MESH:D013610 Tachycardia Amiodarone 4.8011238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.7019225199
MESH:D013959 Thyroid Diseases Amiodarone 5.4819731979
MESH:D013971 Thyrotoxicosis Amiodarone 5.4218020914 19584973
MESH:D016171 Torsades de Pointes Amiodarone 4.8211989578 17467628
MESH:D014178 Translocation, Genetic Valproic Acid 5.9617262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 5.153119515
MESH:D014564 Urogenital Abnormalities Valproic Acid 5.208888407
MESH:D014605 Uveitis Cyclosporine 4.711336536
MESH:D014985 Xerophthalmia Cyclosporine 5.1617120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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