AutismKB 2.0

Annotation Detail for GAB1


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Basic Information Top
Gene Symbol:GAB1 ( - )
Gene Full Name: GRB2-associated binding protein 1
Band: 4q31.21
Quick LinksEntrez ID:2549; OMIM: 604439; Uniprot ID:GAB1_HUMAN; ENSEMBL ID: ENSG00000109458; HGNC ID: 4066
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04012ErbB signaling pathway
hsa04722Neurotrophin signaling pathway
hsa05211Renal cell carcinoma
hsa05100Bacterial invasion of epithelial cells
Pathway IDPathway Name
Signaling by EGFR
Signaling by Insulin receptor
Signaling by FGFR
Pathway IDPathway Name
200183Trk receptor signaling mediated by PI3K and PLC-gamma
200189FGF signaling pathway
200032Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
200128Neurotrophic factor-mediated Trk receptor signaling
200156Signaling events mediated by Stem cell factor receptor (c-Kit)
200157EPO signaling pathway
200151VEGFR1 specific signals
200127PDGFR-beta signaling pathway
200085EGF receptor (ErbB1) signaling pathway
200065Signaling events mediated by TCPTP
200161Signaling events mediated by VEGFR1 and VEGFR2
200011LPA receptor mediated events
200113ErbB1 downstream signaling
200058Signaling events regulated by Ret tyrosine kinase
Pathway IDPathway Name
P00018EGF receptor signaling pathway
P00047PDGF signaling pathway
Pathway IDPathway Name
500514Gab1 signalosome
500251PI-3K cascade
500248FRS2-mediated cascade
500247Downstream signaling of activated FGFR
Related Diseases/Disorders Top
No data
No data
Desease Name
gastric atrophy H. pylori infection
INFECTION
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of GAB1 mRNAincreases expression 19933214
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene results in decreased expression of GAB1 mRNAdecreases expression 20406850
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of GAB1 mRNAaffects expression 17484886
D004041 Dietary Fats Dietary Fats results in increased expression of GAB1 mRNAincreases expression 18042831
D002117 Calcitriol Calcitriol results in increased expression of GAB1 mRNAincreases expression 16002434
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of GAB1 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of GAB1 mRNAdecreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of GAB1 mRNAaffects cotreatment|decreases expression 17942748
D006820 Hyaluronic Acid Hyaluronic Acid results in increased phosphorylation of GAB1 proteinincreases phosphorylation 16864594
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of GAB1 mRNAincreases expression 19339665
D008070 Lipopolysaccharides methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of GAB1 mRNA]increases expression|increases reaction 19339665
C008435 methyldithiocarbamate methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of GAB1 mRNA]increases expression|increases reaction 19339665
C041786 palm oil palm oil results in increased expression of GAB1 mRNAincreases expression 18042831
C059514 resveratrol resveratrol inhibits the reaction [AGT protein results in increased phosphorylation of and results in increased localization of GAB1 protein]decreases reaction|increases localization|increases phosphorylation 15849355
C059514 resveratrol resveratrol inhibits the reaction [EGF protein results in increased phosphorylation of and results in increased localization of GAB1 protein]decreases reaction|increases localization|increases phosphorylation 15849355
D013629 Tamoxifen Tamoxifen affects the expression of GAB1 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of GAB1 mRNAaffects cotreatment|decreases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of GAB1 mRNAincreases expression 19933214
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.6814745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.9615322242 14514962 11752688
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.0817505938
MESH:D058186 Acute Kidney Injury resveratrol 3.9316538975
MESH:D055371 Acute Lung Injury Lipopolysaccharides 4.1211850527 18653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8314692618
MESH:D000236 Adenoma resveratrol 3.3615688382
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.4916835633
MESH:D000544 Alzheimer Disease resveratrol 2.5816162502 16183991
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.0211748828
MESH:D001161 Arteriosclerosis Dietary Fats 10.2615238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 10.2611256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.5215885639
MESH:D001169 Arthritis, Experimental resveratrol 7.5217115116
MESH:D050197 Atherosclerosis resveratrol 3.3216873680 17967414
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.1212125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.9215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.8115746008
MESH:D002545 Brain Ischemia resveratrol 4.4017600658
MESH:D001943 Breast Neoplasms Calcitriol 2.3611237771
MESH:D001943 Breast Neoplasms Dietary Fats 2.3620435547
MESH:D001943 Breast Neoplasms resveratrol 2.3616393696 17651959 17534123
MESH:D001943 Breast Neoplasms Tamoxifen 2.3617242785 15668708 16818667 19142967 19289846 19189210 19244106 19189212 19288272 19066611 18425577 20544844 21138602 19221464 16273361 19115204 19410462 18997820 20390343 18855134 20859285 20135344 17261762 18351453 20005174 18815881 17049068 11161223 18984771 15565566 19059307 16202921 19487384 18629630 19103187 20065188 17440819 19084267 19200415 19155303 16873071 19011961 21152245 18821012 17893378
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.3620435547
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.8816192424 16227642 3786805 15700767 16050911 15673190 18705752 15721981 16011737 16124888 16097048 10355542
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8616835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.6119066611
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 6.7016705839
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 6.7018788625
MESH:D006528 Carcinoma, Hepatocellular resveratrol 6.7019321006 16227395
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 6.7016924424
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.7116675471
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 5.0111237771
MESH:D002294 Carcinoma, Squamous Cell resveratrol 5.0116227395
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.6917572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.4118850075 18670907 16120746
MESH:D002318 Cardiovascular Diseases resveratrol 3.5315458977
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 2.826135515
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.2316835633
MESH:D002779 Cholestasis Ethinyl Estradiol 2.9317110522 16919318 15861022 16105132 17333356 17681005 11677210
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1315668235 12621046 15340226 16354765 8697196
MESH:D003092 Colitis resveratrol 4.2316474422
MESH:D003110 Colonic Neoplasms resveratrol 2.4716338953
MESH:D015179 Colorectal Neoplasms resveratrol 2.2216550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.1317141729 14669216
MESH:D003327 Coronary Disease resveratrol 3.8016507316
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2620055451 10048152 15322242
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.1218551238
MESH:D003711 Demyelinating Diseases Tamoxifen 4.4719031437
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.8416873680
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6817107852
MESH:D003928 Diabetic Nephropathies resveratrol 9.2916286809
MESH:D003928 Diabetic Nephropathies Tamoxifen 9.2919279558
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 6.3118551238 21346803
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 6.3116177239 4309450 11566570 15968718 19336974 7179309 6884620 7440962 6623471 15027814 10092053 19085960 3786805 2869522 15998439 9327722 3732212 10915739 7120509 17522070 21278145 16227642
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 6.3120420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.8211462148
MESH:D050171 Dyslipidemias Dietary Fats 3.5118367378
MESH:D004487 Edema resveratrol 7.138985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 7.1311000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.0418230668 16714409 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 22.7715138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 22.7712538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 22.7717872969
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 22.7719031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 3.1016202921 20544844 17893378 19155303
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.109294722 10568697
MESH:D019446 Endotoxemia Lipopolysaccharides 4.5117637181 15821434 15328337
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.9517923197
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.0711564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 19.4719224547 12631006 17595544 12795759 16239168 15959796 61145 16045604
MESH:D005234 Fatty Liver Dietary Fats 19.4718296743 17967931 19551842 19004024
MESH:D005234 Fatty Liver Ethinyl Estradiol 19.4715345470
MESH:D005234 Fatty Liver Tamoxifen 19.4714986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.2816709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5611858732
MESH:D005334 Fever Lipopolysaccharides 4.099205823 11852909
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.6414745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.3019069698
MESH:D005355 Fibrosis Carbon Tetrachloride 15.3918705752
MESH:D005355 Fibrosis Dietary Fats 15.3918296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 15.3920067830
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.7310696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.3710048152 11294989
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 4.4616366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.4211000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.6919900420 19110552
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.0016120746 15340226 12621046
MESH:D006561 Herpes Simplex resveratrol 4.3016876885
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.1816959395 15340226 16354765 8697196 18606429
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.6516899240
MESH:D006937 Hypercholesterolemia Dietary Fats 9.4921332399
MESH:D006937 Hypercholesterolemia resveratrol 9.4917188708
MESH:D006949 Hyperlipidemias Dietary Fats 9.5821332399
MESH:D006949 Hyperlipidemias resveratrol 9.5816873680
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9318850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.1915338365
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.3817488730
MESH:D007021 Hypospadias Ethinyl Estradiol 3.9116945680 16569931
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.7517600658
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.5512013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.5417937319
MESH:D007249 Inflammation Dietary Fats 16.3220412841
MESH:D007249 Inflammation Lipopolysaccharides 16.3217237260 17255318 12878042 17963957 9205823
MESH:D007249 Inflammation resveratrol 16.3216366677
MESH:D007249 Inflammation Tamoxifen 16.3219457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 16.3212878042 12200463
MESH:D007251 Influenza, Human resveratrol 4.6816624496
MESH:D007333 Insulin Resistance Dietary Fats 3.1511836018 18457598
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.7217255318
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.4216580747
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 7.6116705839
MESH:D007680 Kidney Neoplasms Tamoxifen 7.6118625569
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 3.6316087638
MESH:D007970 Leukopenia Lipopolysaccharides 4.8115821434
MESH:D008064 Lipidoses Tamoxifen 3.2117567588 15342952
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 6.7711903743 17157831 11408273 17174718 16943688 16221502 16239168 17334410 21278145
MESH:D008103 Liver Cirrhosis Dietary Fats 6.7718296743
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 5.0418412020 18279442 16638106 17721639 17698563 17761835 18054572 13678700 12649538 17805973 18472094 16248980 17922224 15673190 17557913 12632514 17714472 10355542 15931870 18205269 16015684 15338365 12445418 18210741 18251166 15730626 18376398 17708605 18395914 18166357 14512876 17976157 15370692 14724832 12666154 15959796 17823541 15893842 14716496 18339082 12546737 15996030 15818738 17766677 15925388 12958196 14620537 15123356 18006644 15876570 12898905 17900296 12389079 16027843 15052691 17640975 12632512 12586293 12741479 15057751 18418968 16192424 15362042 18277467 12609069 18705752 16116963 16136751 17481882 16011737 17525996 18481824 18156304 16033810 17631135 12445421 17944888 16097048 14748882 18187930 17565644 15650968 20821823 11481614 18472332 18420326 12667390 14716833 18429990 18317297 18395095 17869086 18263696
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 5.0412878042
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 5.0418564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 5.0412878042
MESH:D008107 Liver Diseases Carbon Tetrachloride 2.1017285989 15720792 16964402 16246199 15830285
MESH:D017093 Liver Failure Carbon Tetrachloride 4.2715123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.7714706259 16899240
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 14.567678174
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 14.5619294768
MESH:D008113 Liver Neoplasms resveratrol 14.5620405173 19812893 19321006 19073162
MESH:D008113 Liver Neoplasms Tamoxifen 14.5616684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 14.5616984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 10.072876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 10.0712014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 10.0712151625
MESH:D055370 Lung Injury Lipopolysaccharides 4.1121114838
MESH:D008175 Lung Neoplasms Tamoxifen 2.2718625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 2.2719555203 11884234
MESH:D016393 Lymphoma, B-Cell resveratrol 4.3917088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.9414749477
MESH:D015674 Mammary Neoplasms, Animal resveratrol 10.4015688416
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 10.4019428831
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 6.348985016 11606380
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 6.3416827153 11731420 19196722 14580682 19196723
MESH:D020149 Manganese Poisoning Tamoxifen 4.6819453300
MESH:D008545 Melanoma resveratrol 3.4817992120
MESH:D008545 Melanoma Tamoxifen 3.4812393984 19393235
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.3015990972
MESH:D008659 Metabolic Diseases resveratrol 4.4617112576
MESH:D009101 Multiple Myeloma resveratrol 3.5214749477 17164350 16267019 16490592 17935668 17049120
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.9917962980
MESH:D009203 Myocardial Infarction resveratrol 3.0617125593 17188708 16456233 16525036 17015251 16317513
MESH:D017202 Myocardial Ischemia resveratrol 9.2317015251 17125593
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 9.2312213967
MESH:D009205 Myocarditis resveratrol 4.8817322642
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.987678174 18551238
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.5719393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5419410462
MESH:D009374 Neoplasms, Experimental resveratrol 4.108985016
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.1319200415 19189210 19196722
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.3114600291
MESH:D019636 Neurodegenerative Diseases resveratrol 3.8717652729
MESH:D020078 Neurogenic Inflammation resveratrol 4.4917929310
MESH:D009765 Obesity Dietary Fats 2.3017217161 21332399 20132043 19632207 16723640 11836018 20518802 18457598 18674790
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.5116049721
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 4.3417513867
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.7711578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.3812520081
MESH:D011014 Pneumonia Lipopolysaccharides 4.6711605937 12224865
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.6518163543
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 9.9916679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 9.9911399792 11896295 11118676 11222880
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.9015572423
MESH:D011471 Prostatic Neoplasms Calcitriol 2.1812479363 16289102 16644109 18247401 15754350
MESH:D011471 Prostatic Neoplasms Hyaluronic Acid 2.1816864594
MESH:D011471 Prostatic Neoplasms resveratrol 2.1817636462 16731767 17804756 15767336 17675339 17718901
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.1815067354
MESH:D011537 Pruritus Ethinyl Estradiol 3.4315861022 16919318
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.7216325855
MESH:D015427 Reperfusion Injury resveratrol 3.3116314181 15827377 17520802 17058453 16317513
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.7810835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.9318990726
MESH:D012640 Seizures 2,6-dinitrotoluene 2.5918551238
MESH:D012878 Skin Neoplasms resveratrol 5.8415837718 8985016
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.8416192470
MESH:D013088 Spermatocele Ethinyl Estradiol 12.0116709447
MESH:D013088 Spermatocele Tamoxifen 12.0116709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.1519457130
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.5616321402
MESH:D013921 Thrombocytopenia Lipopolysaccharides 4.2415821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.7111994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.2215669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.0412697716
MESH:D014062 Tongue Neoplasms resveratrol 4.2916227395
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 5.1316049721
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 5.1317572228 16712894 8653321
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.4310091137
MESH:D002583 Uterine Cervical Neoplasms resveratrol 4.1817473185
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 9.8214692618
MESH:D014594 Uterine Neoplasms resveratrol 9.8217044934
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.7312125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.6214671159 15869587
MESH:D018487 Ventricular Dysfunction, Left resveratrol 4.4117488730
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.3815886252
MESH:D015430 Weight Gain Dietary Fats 3.8116723640
Pathway ID Pathway Name
KEGG:05100 Bacterial invasion of epithelial cells
KEGG:04012 ErbB signaling pathway
KEGG:04722 Neurotrophin signaling pathway
KEGG:05211 Renal cell carcinoma
REACT:9417 Signaling by EGFR
REACT:9470 Signaling by FGFR
REACT:498 Signaling by Insulin receptor
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA28477
    • No data
    Releated disease ID Related disease Name
    PA443622Carcinoma, Non-Small-Cell Lung
    PA444818Lung Neoplasms
    PA443560Breast Neoplasms
    Releated drug ID Related drug Name
    PA10804imatinib
    PA134687924erlotinib
    PA131301952gefitinib
    PA152241907lapatinib
    PA152241908PHA-665752
    PA448478l-arginine
    PA450635nitric oxide
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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